Protein
DNA repair helicase XPB-R
Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function
ATP-dependent 3'-5' DNA helicase involved in nucleotide excision repair (NER) of damaged DNA. XPB-R is a paralog of XBP, but is not a component of the TFIIH basal transcription factor and is dispensable for RNA polymerase II transcription.
Similarity
Belongs to the helicase family. RAD25/XPB subfamily.
Sequence
MQCLFLEERIKKEGCVVLFAEAFRPSFANIQGFLTTIAEPVSRLSLMHEYRMTYFSLGAAASASISVSEVIQFLDDHVYFFRDKCFASYRESVCAFAEMYMSRCNLARVVIDESRTLLECKDIVTAKTLLKDRVVRSLCCQPKETVGEDACPHFLLKSRAAARVVAERCVLLGYPLQQQYEYEKDTSIRNVNIALKSQTRPRPYQIAAVDAAASDGALRSGCIVLPCGSGKTLVGIMLLCKVKKPTLILCAGGVSVEQWRNQILEFASVCAPANNEEGDPSNSTTGEKVRTAAVGAARISCLTGKQKDEITDETDIVLTTYSMLVTAHKAQARCQVEGFEMNADGRGRNPRRANPKERLFQPYGLLIMDEVHMMPADAYKDSLGFINAKGVVGLTATYVREDSKIRDLFHLVGPKLFDISWERLASSGYLAHVTCIEVLTPLARRFSLEYLERSSELTSPQHGTPLLVMLAAANPNKMLCVMEIVKRHVAESSKILVFCDHIMLLKEYSKLLGAPVVCGDTPHRERLMIFSDFQSTSKVNVVCLSRVGDVSVNLPSANVVVQVSSHGGSRRQEAQRLGRILRPKEKASNGKPTDAWFYTVISTDTVEMSYAAHRTAFLVDQGYTCSVTEFNPDGAPEAAVEGVDDTAPGDVVSIRQAKLRGTFKKQELKCSVASPTAQGSVNPRSLDYQEKLLCRVVASWELDYQNATSQQNEPGVANDTATGLIDKKMKRARDETAEDIKREWNSGAQTTQPRGDFCRLPLQRLVGANDDVVYHES