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VAX1

Gene
Vax1
Protein
Ventral anterior homeobox 1
Organism
Mus musculus
Length
338 amino acids
Function
Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
Similarity
Belongs to the EMX homeobox family.
Mass
35.167 kDa
Sequence
MFGKPDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSGSGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAAATAPGPAGAASQHQPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD

Gene
Vax1
Protein
Ventral anterior homeobox 1
Organism
Rattus norvegicus
Length
336 amino acids
Function
Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity).
Similarity
Belongs to the EMX homeobox family.
Mass
35.012 kDa
Sequence
MFGKTDKMDVRCHSDTEAARVSKNAHKESREIKGAEGSLPAAFLKEPQGAFSASGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAATAPGPAGAASQHPPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD

Gene
VAX1
Protein
Ventral anterior homeobox 1
Organism
Homo sapiens
Length
334 amino acids
Function
Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity).
Similarity
Belongs to the EMX homeobox family.
Mass
34.713 kDa
Sequence
MFGKPDKMDVRCHSDAEAARVSKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAEDCNKSKSNSAADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAPGPAGAASPHPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD

Gene
VAX1
Protein
Ventral anterior homeobox 1
Organism
Gallus gallus
Length
327 amino acids
Function
Transcription factor that plays a role in establishing dorsal-ventral polarity in the neural retina.
Similarity
Belongs to the EMX homeobox family.
Mass
34.141 kDa
Sequence
MFGKQDKMDVRCSTETEANRVSKNGHKEGKDSKGAEGNISTSFLKEQQGTFSASAATEDCNKSKSGSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPGLLPPCASGALGSALRGPGLAAGSGTAAAAAAAAAAAPAGGSPHPPSAGTAAGPPPPAALHGAAAAAAGHGLFGLPVPTLLGSVAGRLSSAPLAVAGSLAGNLQELSARYLSSSAFEPYSRTNNKESAEKKALD

Gene
vax1
Protein
Ventral anterior homeobox 1
Organism
Danio rerio
Length
317 amino acids
Function
Transcription factor that is required for closure of the choroid fissure and together with Vax2 is required for optic nerve differentiation and to limit retinal development to the optic cup.
Similarity
Belongs to the EMX homeobox family.
Mass
33.94 kDa
Sequence
MEVRYSQDSESGMLLKNGLKEGKEGKDSQGSISKTFLKDQQESFSPSGAVENCEKSRASSGDPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLTPPGLPGLLPHCGSSSLGSALRGPSLGITANGGSSSSSRSSAGSSGTAGGSPPLPTVTSSGTVTGLQGSPPAHGLFSFPMPSLLGSVASRISSTPLGMAGSLAGNLQELSARYLCSSAFEPYSRTNGKEALDKKVLE