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UL131A

Gene
UL131A
Protein
Protein UL131A
Organism
Human cytomegalovirus (strain Merlin)
Length
129 amino acids
Function
Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells (PubMed:23853586, PubMed:17942555). Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection (PubMed:30057110). Contributes to the formation of the complex between UL128, UL130 and gH-gL.
Mass
14.989 kDa
Sequence
MRLCRVWLSVCLCAVVLGQCQRETAEKNDYYRVPHYWDACSRALPDQTRYKYVEQLVDLTLNYHYDASHGLDNFDVLKRINVTEVSLLISDFRRQNRRGGTNKRTTFNAAGSLAPHARSLEFSVRLFAN