TTC7A

Tetratricopeptide repeat protein 7A

858 amino acids

Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:24417819). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions (By similarity).

96.185 kDa

MAAKGAHGSYLKVESELERCRAEGHWDRMPELVRQLQTLSMPGGGGNRRGSPSAAFTFPDTDDFGKLLLAEALLEQCLKENHAKIKDSMPLLEKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLKGCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEESSFATQALRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGLTMKKQSGMHLTLPDAHDADSGSRRASSIAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVLPFSIIPREL

Ttc7a

Tetratricopeptide repeat protein 7A

858 amino acids

Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity). In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions (By similarity).

96.156 kDa

MAAKGAHGTHLKVESEVERCRAEGQWDRMFELARHLQMLGISGGGSSNRRNSPSGRFTTLDTDDFVKLLLAEALLEQCLKDNHDKIKNSIPLLEKTDHRLNEAKDHLSSLLNNGKLPPQYMCEAMLILGKLHYVEGSYRDAVSMYARAGIDDISVENKPLYQMRLLSEAFVIKGLSLERLPNSVASHIRLTEREEEVVACFERASWVAQVFLQELEKTSNNSTSRHLKGSLSPDYELSYFLEAALQSAYVKNLKKGNIVKGMRELREILRTVETKATQNFKVVAAKHLAGVLLHSLSEDCYWSPLSHPLPEFMNKEENSFVTQTLRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRAPEQAEDRKVSLQNASAIYDLLSITLGRRGQYVMLSECLERAMKCAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSDPTVPLMAAKVCIGSLHWLEEAEHFATVVIGLGEEAGESLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERARELAPDDPQIIFYVALQLALVRQISSAMERLQEALTMCRDDANALHLLALLFSAQKYYQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQTLYNFSQLGGLEKDGSFEGLTVKKQNGIHLTLPDAHDADSGSRRASSIAASRLEEAMSELTLTTSVLKQGPMQLWTTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVRIMHSLGLMLSQLGHKSLAQKVLRDAVERQSTFHEAWQGLGEVLQDQGQNEAAVDCFLTALELEASSPVLPFSIIAREL