Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity). In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via direct interactions (By similarity).

858 amino acids

MAAKGAHGTHLKVESEVERCRAEGQWDRMFELARHLQMLGISGGGSSNRRNSPSGRFTTLDTDDFVKLLLAEALLEQCLKDNHDKIKNSIPLLEKTDHRLNEAKDHLSSLLNNGKLPPQYMCEAMLILGKLHYVEGSYRDAVSMYARAGIDDISVENKPLYQMRLLSEAFVIKGLSLERLPNSVASHIRLTEREEEVVACFERASWVAQVFLQELEKTSNNSTSRHLKGSLSPDYELSYFLEAALQSAYVKNLKKGNIVKGMRELREILRTVETKATQNFKVVAAKHLAGVLLHSLSEDCYWSPLSHPLPEFMNKEENSFVTQTLRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRAPEQAEDRKVSLQNASAIYDLLSITLGRRGQYVMLSECLERAMKCAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSDPTVPLMAAKVCIGSLHWLEEAEHFATVVIGLGEEAGESLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERARELAPDDPQIIFYVALQLALVRQISSAMERLQEALTMCRDDANALHLLALLFSAQKYYQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQTLYNFSQLGGLEKDGSFEGLTVKKQNGIHLTLPDAHDADSGSRRASSIAASRLEEAMSELTLTTSVLKQGPMQLWTTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVRIMHSLGLMLSQLGHKSLAQKVLRDAVERQSTFHEAWQGLGEVLQDQGQNEAAVDCFLTALELEASSPVLPFSIIAREL

96.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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