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TTC5

Gene
TTC5
Protein
Tetratricopeptide repeat protein 5
Organism
Bos taurus
Length
440 amino acids
Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
Mass
48.918 kDa
Sequence
MMAVEEEEVKEVLQKLQELVDQLYSFRECYFETHSVDDAGRKQQDVREEMEKTLQQMEEVVGSVQGNAQVLMLTGKALNVTPDYSPKAEELLSKAVKLEPKLVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKNKVSLQNLSMVLRQLRTDSGDEHSRHVMDSVRQAKLAVQMDILDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRTASSNPDLHLNRATLHKYEENYGEALEGFSRAAALDPAWPEPWQREQQLLDFLTRLTSFLESKGKVKTKKLQSMLGNLRPAHLGPCGDGRYQSASGQKVTLERKPLNALQPGVNSGAVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNMVQSWGVLIGDSVAIPEPNLRLHRIQHKGKDYSFSSVRVETPLLLVVNGKPQGSSSQAAATVASRPQCE
Protein
Tetratricopeptide repeat protein 5: TTC5

Gene
TTC5
Protein
Tetratricopeptide repeat protein 5
Organism
Homo sapiens
Length
440 amino acids
Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
Mass
48.928 kDa
Sequence
MMADEEEEVKPILQKLQELVDQLYSFRDCYFETHSVEDAGRKQQDVQKEMEKTLQQMEEVVGSVQGKAQVLMLTGKALNVTPDYSPKAEELLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQLRTDTEDEHSHHVMDSVRQAKLAVQMDVHDGRSWYILGNSYLSLYFSTGQNPKISQQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEGFSRAAALDPAWPEPRQREQQLLEFLDRLTSLLESKGKVKTKKLQSMLGSLRPAHLGPCSDGHYQSASGQKVTLELKPLSTLQPGVNSGAVILGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNIVQSWGVLIGDSVAIPEPNLRLHRIQHKGKDYSFSSVRVETPLLLVVNGKPQGSSSQAVATVASRPQCE
Protein
Tetratricopeptide repeat protein 5: TTC5

Gene
Ttc5
Protein
Tetratricopeptide repeat protein 5
Organism
Mus musculus
Length
440 amino acids
Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
Mass
48.795 kDa
Sequence
MMADEEEEAKHVLQKLQGLVDRLYCFRDSYFETHSVEDAGRKQQDVQEEMEKTLQQMEEVLGSAQVEAQALMLKGKALNVTPDYSPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVASAHTCFSGALTHCKNKVSLQNLSMVLRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEGFSQAAALDPVWPEPQQREQQLLEFLSRLTSLLESKGKTKPKKLQSMLGSLRPAHLGPCGDGRYQSASGQKMTLELKPLSTLQPGVNSGTVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVLIGDSVAIPEPNLRHHQIRHKGKDYSFSSVRVETPLLLVVNGKPQNSSSQASATVASRPQCE
Protein
Tetratricopeptide repeat protein 5: Ttc5

Gene
Ttc5
Protein
Tetratricopeptide repeat protein 5
Organism
Rattus norvegicus
Length
440 amino acids
Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
Mass
48.793 kDa
Sequence
MMADEEEEAKQVLQKLQELVDQLYCFRDSYFETHSVEDAGQKQQDVQEEMEKTLRQMEEVLGSVQVEAQALMLKGKALNVTPDYSPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKNKVSLQNLSMVLRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRLTNLLASKGKTKPKKLQSMLGNLRPAHLGPCGDGRYQSATGQKVTLQLKPLSTLQPGVNSGTVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVLIGDSVAIPEPNLRHHQIQHKGKDYSFSSVRVETPLLLVVNGKPQNSSSQASATVASRPQCE
Protein
Tetratricopeptide repeat protein 5: Ttc5