TMEM201

Transmembrane protein 201

666 amino acids

Isoform 2: May define a distinct membrane domain in the vicinity of the mitotic spindle (PubMed:19494128). Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina (PubMed:21610090).

Belongs to the TMEM201 family.

72.236 kDa

MEGVSALLARCPTAGLAGGLGVTACAAAGVLLYRIARRMKPTHTMVNCWFCNQDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYLEHLNHVVSSAPSLRDPSQPQQWVSSQVLLCKRCNHHQTTKIKQLAAFAPREEGRYDEEVEVYRHHLEQMYKLCRPCQAAVEYYIKHQNRQLRALLLSHQFKRREADQTHAQNFSSAVKSPVQVILLRALAFLACAFLLTTALYGASGHFAPGTTVPLALPPGGNGSATPDNGTTPGAEGWRQLLGLLPEHMAEKLCEAWAFGQSHQTGVVALGLLTCLLAMLLAGRIRLRRIDAFCTCLWALLLGLHLAEQHLQAASPSWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRFFPGDSAGLFPTSPSLAIPHPSVGGSPASLFIPSPPSFLPLANQQLFRSPRRTSPSSLPGRLSRALSLGTIPSLTRADSGYLFSGSRPPSQVSRSGEFPVSDYFSLLSGSCPSSPLPSPAPSVAGSVASSSGSLRHRRPLISPARLNLKGQKLLLFPSPPGEAPTTPSSSDEHSPHNGSLFTMEPPHVPRKPPLQDVKHALDLRSKLERGSACSNRSIKKEDDSSQSSTCVVDTTTRGCSEEAATWRGRFGPSLVRGLLAVSLAANALFTSVFLYQSLR

Tmem201

Transmembrane protein 201

664 amino acids

Isoform 3: Proposed to be involved in actin-dependent nuclear movement; via SUN2 associates with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow.

Belongs to the TMEM201 family.

72.5 kDa

MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKPTHTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQPQQWVSSQVLLCRRCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEYYIKHQNRQLRALLLSHQFRRREADQAHGQSFSSSAVKAPFQVILLRALAFLACAFLLFTTLYGPSEPFTPGAALPPALPPGGNSSAASDNTTSQAEGWQQLLGLLPEHATEKLHEAWAFGQSHQTSIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKSTGPRRFRPRRYFSGDSASLFPSSPSLAVPYPSVTSSPASLFIPTPPGFLPLTKQQLFRSPRRVSPSSLPGRLSRALSLGTIPPLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPASPLPSPAPSVASSVASSSGSLRHRRPLISPARLNLKGQKLLLFSSPGEAPNTPSSSEEFSPPNGSLFIESPQLPQRNHTRDTKHTMEMRSMLARDSARSSHSIKKEDESSQSSTCVVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQSLR

tmem201

Transmembrane protein 201

651 amino acids

May be involved in actin-dependent nuclear movement. May be involved in the organization of the nuclear envelope. May recruit Ran GTPase to the nuclear periphery.

Belongs to the TMEM201 family.

72.016 kDa

MEALNQILIEYPPLVVGGVGATAVAAGGALIYRIATRKKPTHLQVNCWFCNQDTVVPYGNRNCWDCPYCEQYNGFQENGDYNKPIPAQYMEHLNHGVSAGVPETPKTLQWVNCQMLLCKKCNNNQTLKIKQLASFIPREDENYDEEIEVYKHHLEQTYKLCRPCQTAVEYYIKHQNRQLRALLFNHQLRRTRDADKAFIKNTYSLSTPAWLILLRILTFLACAFLVAVALSGYVDESPSVTQTLSGGVVPPKRVLQNENESKTDEGSLMWDDLMGLLPEKAVENARLFWQSGSDHQMAVASVGLLTCITGVLMAGPVRLRRIDAVASVLWLLVICFYLAECYLKTDVPSWLEMVKFGITSVCCLVGFAAAVATRKSTSQRRARGRRYLSGGSPGEFFCNHGPLLSAPVSESSTFIPTPPPNLSQLLIRQQSQRTRKASPSSLPGRLNRALSLGTIPSLARADSGFLFSGSRPSSQCKDSPPSDYYSLKSGSRPSSPGPSPTPSVAGSVTSTSSSARQRRPLISPARLNISGQKLRLFSSPLEPFSLASPPPFLSEHNPMHSRGFLPDVPHFHLQNHGSVIDEGSVFEHLEKPMGSSSSSSNCHVDTTTGNNIESKPGWKGFLGMTLWPGLLFASLTINLSFICIYVYYNWR

TMEM201

Transmembrane protein 201

393 amino acids

May define a distinct membrane domain in the vicinity of the mitotic spindle. Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina. Involved in nuclear movement during fibroblast polarization and migration. Proposed to be involved in actin-dependent nuclear movement via association with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow. May recruit Ran GTPase to the nuclear periphery.

Belongs to the TMEM201 family.

43.243 kDa

MEGVSALLARCPTAGLAGGLGVTACAAAGVLLYRIARRMKPTHTVVNCWFCNQDTVVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYLEHLNHVVSGSPGPRAPAQPLQWVSSQVLLCRRCSHHQTAKVKQLAAFSPRDEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEHYIKHQNRQLRALLLSHQFKRREADQTHTQSFCASAVKAPAQVIVLRALAFLACAFLLTTALYGTSNPFAPGAPLPPTLPTGSNGSAPPDNGTATGAEGWRQLLGLLPEHAAEKLREAWAFGQSHQMGVVALGLLTCLLAMLLAGRIRLRRIDAFSTGLWALLLGLHLAEQYLQAASPSWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRSEKQQ