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TIMM21

Gene
Timm21
Protein
Mitochondrial import inner membrane translocase subunit Tim21
Organism
Mus musculus
Length
249 amino acids
Function
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Similarity
Belongs to the TIM21 family.
Mass
28.304 kDa
Sequence
MICAFLRVVQHAEKLHGSLGRQLLPHFVFTKACFKTQPLRWGLREQKITVQPRTVLRFTQKTFWTQGPDPRKAKEDSTKQVSIRRNQREETGVSMSQKVREAGRDVSYLIVVLFGVGLTGGLLYAIFKELFFSSSPNIIYGKALGKCRTHPEVSFLMIVLGRRCASLLKPMLSCFSVFRSHSLMHFDPGTVSYIHFSVVLSAPASSGLRHPSYKTILNQNVAKRVESWQRLHLGHYIVYRIQGILCGPQ

Gene
TIMM21
Protein
Mitochondrial import inner membrane translocase subunit Tim21
Organism
Homo sapiens
Length
248 amino acids
Function
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Similarity
Belongs to the TIM21 family.
Mass
28.202 kDa
Sequence
MICTFLRAVQYTEKLHRSSAKRLLLPYIVLNKACLKTEPSLRCGLQYQKKTLRPRCILGVTQKTIWTQGPSPRKAKEDGSKQVSVHRSQRGGTAVPTSQKVKEAGRDFTYLIVVLFGISITGGLFYTIFKELFSSSSPSKIYGRALEKCRSHPEVIGVFGESVKGYGEVTRRGRRQHVRFTEYVKDGLKHTCVKFYIEGSEPGKQGTVYAQVKENPGSGEYDFRYIFVEIESYPRRTIIIEDNRSQDD

Gene
Timm21
Protein
Mitochondrial import inner membrane translocase subunit Tim21
Organism
Rattus norvegicus
Length
245 amino acids
Function
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Similarity
Belongs to the TIM21 family.
Mass
27.876 kDa
Sequence
MICAFLRVVRHAEKLHGSLGRQLLLPHFVLTKACLKTQPLRWGLREQKKTVQPRTVLGFTQKTFWTQGPDPRKAKEDSSKQVSINRNQREETGVSTSQKVKEAGRDVTYLIVVLFGVSITGSLLYTIFKELFSSSSPNIIYGKALGKCRTHPEVISVFGEPVKGYGEMSRRGRRQHVSFTEYANNGLKRIRVKFYIEGSEPGKQGTVHAEVEENPRSGQFDFRYIFVDVAPKRSIVVEDNRFQQS

Gene
TIMM21
Protein
Mitochondrial import inner membrane translocase subunit Tim21
Organism
Bos taurus
Length
244 amino acids
Function
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Similarity
Belongs to the TIM21 family.
Mass
27.938 kDa
Sequence
MICTLLRAVRCTERLHGCPGKPWFLPHSVPHRACSQTEPRWRWGLQEQNTTARPRCIWGVTQRSIWTQVRSPQSAKEDGSKQVSVHRSQGGETVLSTSQKVKEAGRDFTYLIVVLIGISITGGLFYTIFRELFSSSSPNKIYGKALEKCRSHPEVISVFGEPVKGYGEVTRRGRRQLVSFIEYKKDGLKHMRVKFYIQGSEPGKQGTVHLEVKENPESGEYEFRYIFVELEPYSRTIVVEDNRS

Gene
timm21
Protein
Mitochondrial import inner membrane translocase subunit Tim21
Organism
Xenopus laevis
Length
232 amino acids
Function
May participate in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Similarity
Belongs to the TIM21 family.
Mass
26.066 kDa
Sequence
MLPRFLWRPVLCSYRALGSPSRSLTVSYRNLSCLALLHKGAFAAPTSRSLFCAERPISTGCTSLQVKDKRVSVQSTSDGAPPQNASHKVKEAGRDFTYFIVVLIGIGVTGGLFYVVFEELFSSSSPSKIYGEALEKCRSHPEVIGAFGEPIKGYGETTRRGRRQHVSHMEFVKDGIKCMRLKFYIEGSEPRKQGTVHIEVKENPASGKYEFQYIFVEIDTYPRRTIIIEDNR

Gene
TIMM21
Protein
Mitochondrial import inner membrane translocase subunit Tim21
Organism
Pongo abelii
Length
172 amino acids
Function
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
Similarity
Belongs to the TIM21 family.
Mass
19.287 kDa
Sequence
MICTFLRAVQYTEKLHRSLAKRLLLPHIVLNKACLKTEPSLRCRLQYQKKTVLPRCILGVTQKTIWTQGPSPGKAKEDSSKQVSVHRSQRGGTAVPTSQKVKEAGRDFTYLIVVLFGISITGGLFYTIFKELFSSSSPSKIYGRALEKCRSHPEGRSSHRPRSDVIARICSP