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TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
572 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
63.625 kDa
Sequence
MADETAPKSSKPTAEAAPKKTGYTNPALRAMGIRQLRLPSRNWMIFWTVVGTISGGIYYDRHERKKVRQQYKDAVAYLGERPLGGLEIPRKITVFVAPPPGDYLDHVLTHFRAYIKPILTAAALDFEVKQESRQGEIRYVVAEGIRNYRREQMGLPKVPSRLMVDEEEYNKAVAEQNAEVERLKAGREKHTNPNPTFQAFNSINNRPGAPSSPDSQPEEQMSISVAGTIAQEQLDKEITSKLEFNPESGVICVGRGAYKEYLAGLHEGWLGPLEDPRPDEDNRKVYEEFPNREKDDDDALGLVKTPVEEPTTAVQNVQSVSEHLNSHPEMVKDVSETISHSGDVTAVTDVEQTAAGPVDVVSETASTHDTPAASDNKTPKPLSEMSPSEWDPKAPLPEIKRKPVPKPYIRPEEYSEAELSEFYASGFENASTAHSTVSSNINQQPNDLNSPAGSGTAFVEQFFFSPIAVIPHRHIMGFMNTPLRIARYFNKRAVADEVGAATVVAVTGDTRPFDVKTDPDLLVSEEYDWPSKWVKKGQDNGSEWVQPVVVDQRVMEKVKVYQPKGEGESELK
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
495 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
56.353 kDa
Sequence
MSENPEPSKGSTPNVEGAEKVNKPPVKKGWSNPALRMMGIPKISLPSRNWMIFWTLLASVGGGVAYDRYQQKQIRKKWMEKFEPLGEEAYRTDRIPRKLSVFIAPPPNDYLDSSMVYFRKYVKPLLNASAIDFDVFTENRQGDIRAAVAERIRELRIETNENAKKAQEEAKQEQYDASWTKFFKKDVPNFFTLKFQSNSKEDEALVSSNDLYSPKDVLGLYYLKEPIDAKRDDELNPMEAGGVICIGRGAYKEYMTGVHEGLLGPLEAPEEVRTITEVDPQVTENEPETAHNDNESKAVVELPVLPTDDLPADSVDKQDAVPETPSETAENTPNAEEGDNEKPVPKPFITPDEYPNATYAPEFQNVSLIMNKKNVPVIFEQPVYVFPLPIVSGFLNTHRKLYRFFTKRNVADDYGCRTSVVVQNVSRPFVYKDQFMAKEEELEWPKKWVATGKEKNSEWVQELVTDDRVTTRMKVFDVSLAAKSTDKPIDKPTNE
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
478 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. Its precise function within the TIM22 complex is unclear.
Similarity
Belongs to the TIM54 family.
Mass
54.183 kDa
Sequence
MSSESGKPIAKPIRKPGYTNPALKALGIPALRLPSRNWMIFWSVLTVSIGGIAYDKYKQRQILSHATDLVKPLAEESMEVDKVPRKITVFIAPPPNDYLESSLKVWRRYVKPVLYYAGLDYELVQEDRQGIIRTNVANRIRELRKEILASTDGQPVKEPNQTVAKPSGSSTSKISSLLPFNKIIQDPAEEDDSFDPEIGKKFKENFDWRNVIGIFYTMPKPKHIISEDALTKDPILSGGVICLGRGAYKEYIAGIHEGLLGPIEKTEKTGSTEPKMTGVVEANQIESKVSESGATELVDAEKETALEEAKVQDDLKVDEENSSEDSQKFLKPFISSDQYPDLQIASELQTPNGEFIRNPNTNIPLLINQPLLVIPIPNLIGFTTIPRRIHRFYQKRFYVEDVCSSVVNCVRQTRIRPFDIAKDIDLAKDEEKDWPQNWVKQGKEKNSEWTQELVCDPRITKHMFVYEKPPKEEPESDI
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
472 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
53.34 kDa
Sequence
MMGEFKHPPQEKQKMSSTKKAGYSNPAFAAMGIPALRLPGPKWCAFWLVVGAGIAGVVYDKREQRRICKHYSSLVKDQGAAHMDTWLKPRRLTVFVAPPPGDYLETSMKVWRRYVKQVLFEAGLDYEVFTEERQGVIRHEVAERVRQLRRDIAAAEAAEQRALDEKRWLNRMRSWWRREKLSEEELERIRAQKFRDEFTYKQLLGVFYKNAPLREQKVWDADALVEDPVLAGGVICIGRGAYKEYIAGIHEGTLGPLDPPTLTPEAPTELSAAAEDLTQAPEQPEPSAAAEALKQAPEQAEHSPAEPDSAATDAPDEKSNNAPAPPPAPYVSPDEYSSLSLSQELVGDVRHPSSHIPALFHQPLLVIPVPNLSGFLQTPRKIYRFYTRRYYAEECCKAAAAMVLQTIRPFQPDDLNLGISEEEDWPRRWVEQGRERKSEWVQDLKADPRVIAELHVVDPALMADLAATMNLN
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
471 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
51.943 kDa
Sequence
MWKKLPSPGWLAFGTVVTVAGSGIAYDKYEQSQIRSLYVNHVRNEMSSSLSTNVKPRKLLVLVAPPPNDYLDTSLKLWRRWIKPILHSSGLDYEIVSGTKQGEIRTEIASRVRQLRKELIEQEQQQQHDAQSKKSRSWLDWFKWCRGVSTTPDPVSEESPAASFDTRSVLGIFYHNEPQPVVTEDSLLDPSVAGGVICVGRGAYKEYIAGVHEGILGPLEEPPKVVESDASSVTDTTASAVITENPSVKEISVTQPAETAVAAATVGTTMNETGAVNTDSTPAETIPAETTPTENTPIETTPDESSEEKEGPKISKPYILPSDYANASIPAELSKPLIIDPKTGAPAFFEQPLLVVAVPNLSGFTTIPTRIARFYQKRFLCEQVSHSTLAIVEAKSRPFTTTDLDLSAYEELDWPKSWVESGKERGSEWVQPLQGDDRVLQKFRVVEPAIVPSLQLKEDQSKKQELSPENK
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
tim54
Protein
Mitochondrial import inner membrane translocase subunit tim54
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
468 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
53.075 kDa
Sequence
MADPVPPASTAPPAAPAATTATPPPPPPPPPPKALRPQNQALRMLGLPNLPNKLPSRNWMIFWTVSASITAAIIYDRREKRRNIAKWRHAVEHLAAEPITDKLGLEQPRKLTIYLSAPPGDGLRVAQDHYTEYVKPVLAASGLDWEFVQGRREGDVRAVVAERLRKVRRGWENKEEQDPNREPTKDELIEIYRQQRGIKDYEGVRGDVVIGRHTWKEYLRGLHEGWLGPLVAPAEPAPLPPTPAPAAAEGSTSTEDKPAEEKKEEEAPKPKRPPQPKPYNTTSDYSSETLHPLTPQELTPAVPIREPHILGFLNTPTRMVRFFNRRSLADDIGREVAAVCLATHREFQQQTNPDAPSTDSVQYEQAKELEWEEQDWPKKVWKEDEADADKEVTEKIHIKPVVMDPRLAHRMRRFALTPEDEDRVSKIKVPEEEVEGWIKGSLRKACHWGYDKAFNKKKLVPLEDKDVE
Protein
Mitochondrial import inner membrane translocase subunit tim54: tim54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
458 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
51.693 kDa
Sequence
MADLTPGARKPAPAELTGFRSALAHTGIPHGVLLWKPRLPSRNWLVFWSVSLSLSYAYYYDRAECKRIKQEVVERVEKYGREPMPGGSLGEPRRVVVWAGRWGGDDDADRAGRYFRKYVKPYLVAAGIDYTLPSVPLHGSITRQLHAAILLQRRQALGLAPTATPLSLPGVLDPAEAKRREVESGVVVVGRASLKEYLEGLRRGWECGVDEWAWETEVEKTLAGDGVFESVESPVEPAVETAETVVEPTADAVPKSNFGFLARPAPVTPGAPAIPAHLHTPPSPLPPTPPLLLLPFTNHLGFLQLPYMILDFFNERAKVRQGAQSALALIEGPTRDMHREDAEHWEEKSESWYNKTARQLPERLQKSRTEYYEAIKSRIDLARAYENGDREMTEEEKKANKVERIQDIQAERLKKELRWKGSEEGWEIVKPETPATWRDRWEGWLKVYQVPEDAQKGL
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
458 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
51.693 kDa
Sequence
MADLTPGARKPAPAELTGFRSALAHTGIPHGVLLWKPRLPSRNWLVFWSVSLSLSYAYYYDRAECKRIKQEVVERVEKYGREPMPGGSLGEPRRVVVWAGRWGGDDDADRAGRYFRKYVKPYLVAAGIDYTLPSVPLHGSITRQLHAAILLQRRQALGLAPTATPLSLPGVLDPAEAKRREVESGVVVVGRASLKEYLEGLRRGWECGVDEWAWETEVEKTLAGDGVFESVESPVEPAVETAETVVEPTADAVPKSNFGFLARPAPVTPGAPAIPAHLHTPPSPLPPTPPLLLLPFTNHLGFLQLPYMILDFFNERAKVRQGAQSALALIEGPTRDMHREDAEHWEEKSESWYNKTARQLPERLQKSRTEYYEAIKSRIDLARAYENGDREMTEEEKKANKVERIQDIQAERLKKELRWKGSEEGWEIVKPETPATWRDRWEGWLKVYQVPEDAQKGL
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
452 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
51.732 kDa
Sequence
MNPALKALGLGNFKLPSRNWTIFWTVLAGSLGGVGYDKYQQRQIISRYCDEVKPLSLQHCDVNKSPRKITVFIAPPPNDYLETSLKIWRRYIKPVLYYAGLDYEVIEEDRQGIIRSEVASRIRQLRRELLEADNEQQGNSGDSLLSIFKKPHAKDPEEEQKFDPEQARQFKADFDFRNVMGIYTKVPKLDTIVQTDSLVADPVLAGGVVCVGRGAYKEYITGLHEGLLGPLDPPEETTQEVEMGSKLKSMNDGDNVETTVETAVETMVETTLESADKVEVEGKDTENEEGKDEPDEEKSRVLKPYLLRTAFHDTPIPPEVEPVLEKDALLKDPKTNVPSLLHQPVLVIPVPNLIGFLTIPERIYRFYQRRFFVDEVCREASNLVKQEHIVKYEPDKHINLALEEESDWPKQWVKTGIEKNSEWTQELVQDQRVVSKMHVFELPKHTTKDTKE
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
tim54
Protein
Mitochondrial import inner membrane translocase subunit tim54
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
445 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
50.011 kDa
Sequence
MPNFRLKLPSRNWMIFLTVTGSFTAALVYDRKQKKRAQQKWCDLVAHLSKESLPVDQTRRKLTVFLSAPPGDGLRVAREHFKEYVKPILVAAALDYQVIEGRREGEIRAGLAERIRKFRRKSGEPSTVVEETGIEEVVADAREKIGVVEEPVPKGDLIIGRNTWKEYIRGLHEGWLGPLDPPQPPLSTDVPSPSEGAETNGSPDDTPTAENSEKKEEPEKKDEKPSKPTGPTPAYITPADYSSQSLPRSLPQSLDGSVPIQFPHILGFLNTPIRIYRYLNQRYLADSVGREVAGIVLASTTRPYSDGSFSTDSELTPAGIDGAPASDNLLGGNYEQKTLLEEEEKDWHKSAHKKDEANPDKEREWVDSVVLDPRIAARMQRYVLSPEDEARSQRIAEGAEYILGEERPTPVPFWQRMWIKYGYGEDEETLKRKPIIGNIDGEDDQ
Protein
Mitochondrial import inner membrane translocase subunit tim54: tim54

Gene
tim54
Protein
Mitochondrial import inner membrane translocase subunit tim54
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
439 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
49.151 kDa
Sequence
MIFFTITGSLTAAIVYDRRERRRVQQKWCDLVAHLSKETLPIEQTRRKLTIFLSAPPGDGLRIAREHFKEYVKPILVAAALDYTVIEGRREGDVRAALAERIRKHRRKAGEPSSVVEEMSNEDIIADARQKIGVVEEPGPKGDLVIGRHTWKEYIRGLHEGWLGPLDPPSPPDAPVKGPSVPVEGSETPADGTPAEENTEKKEEAEKKDDKPAKPSGPTPAYVSPAEYSSRSLPPTLPQSLDSSVPIPFPHLLGFLNTPIRLYRYLSRRHLADEIGREVAGLVLASSSRPYHDGSFSSDSELSGAMVDAGASTLSSPDDMMPSSSAKYEQQTVLEKEESEWHKSVHKRDEENPDKEREWIDDIVLDPRIASRMQRSLLSADEEARSQRITEGKEYILGEERPAPVSFWQRMWIKYGYGEDEETIRMKPIIGNLDGADGE
Protein
Mitochondrial import inner membrane translocase subunit tim54: tim54

Gene
TIM54
Protein
Mitochondrial import inner membrane translocase subunit TIM54
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
400 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
46.113 kDa
Sequence
MPDANEVKPKKGWSNPALRMMGIPRISLPSRNWMIFWTVVTTIGGGIAYDKYEQKQMRKKWMDAVKQFGEVSYGANEIPRKLSIFIAPPPNDFLDESLKLFRKFIKPVLNAGVVDFEIFSESRQGDIRASVAEKIRELRRKQLVEETPKKNESNGNQDNDEEELKSRSDLYKAKDVLGLYKVFPADINVKSEDAIDDSSAGGIICVGRGAYKEYLSGVHEGLLGPLEKPQSVIDEETKLAEEKKKEKEENPDKDDDNDEEQSNLKPVPLRYIKPEDYANAQLAPELDLSTVVKDDKGVPVFFEQPVYTFPLPNLVGFTNIPRKIYRYFTKRFLVDDFGERTATIVNNKSRPFVYKDVLMAKEEEMDWPKKWVEKGKERNSEWVQELEHDERVTSRMKVFE
Protein
Mitochondrial import inner membrane translocase subunit TIM54: TIM54

Gene
tim54
Protein
Mitochondrial import inner membrane translocase subunit tim54
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
347 amino acids
Function
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
Similarity
Belongs to the TIM54 family.
Mass
39.803 kDa
Sequence
MLKTIKSYMPGRNMSIFLGFVAGISGAIYYDRRQKNLIIEKYCSQVRHLADQPMAPLELPRKLKVYLHGPPGDGIYVAREEFEEYIRPIFNAAAIEFETVESKGEGNLLEQVARTVYNKRHNISEVSEPEKNLLSVLKPSVDPPAIVLLGRHALKEFLYGVRYGFSDDIMKRKLETEKLEANNKEEKEEKEGKDDKDDKEDSNDTKNDKKISKNEVDSSLIEASPLTGQVPPKFLDTIAIFPLPNLLGFSNTPKRLSRFFKRRELADELGAIAVNVALSRDVTKFPKQDGTLLLAEEETDWPKQFFTRSDLENRIWTAPFLQDSDEIRFFENIDIFDSTKAKQDKYE
Protein
Mitochondrial import inner membrane translocase subunit tim54: tim54