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TIM10

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
140 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
15.622 kDa
Sequence
MSFLGLGGQNPNGPSNPQKLLAAEAELDMVTDMFNRLVESCHEKCIKADYSSGDLNANEGLCLDRCVAKYFDVNTKVGEVSMRGADGNYGLEDTANTVHAEAWKQRILHGPTLNVKYVHRIKVHEIVRLTMVYLAPWHFN

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
102 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
11.054 kDa
Sequence
MSFLFGGNNRSVEGSVDPAKIEMAVAELDMITDVFNRLVNSCHTKCISSTPLNHRYAEGDLLKGESVCIDRCTAKFFEVNKKVGERMSAMGSAAQATGSFGR

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
102 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
11.054 kDa
Sequence
MSFLFGGNNRSVEGSVDPAKIEMAVAELDMITDVFNRLVNSCHTKCISSTPLNHRYAEGDLLKGESVCIDRCTAKFFEVNKKVGERMSAMGSAAQATGSFGR

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
95 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
10.504 kDa
Sequence
MSFLGMGRPQPTSEQKIAAVESEMRMMADTYNRLQQSCQKKCVPNDYREGELNKGESVCLDRCTAKFLDTSMKVSEIMQQQGQALGGQQGGGGMF

Gene
tim10
Protein
Mitochondrial import inner membrane translocase subunit tim10
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
93 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
10.235 kDa
Sequence
MSFLFGGPPKMSSAEKIAAAETEVEMVSDMFNRLTESCQKKCIPNDYREGDLNKGESVCLDRCVSKFFEVNIKVSEKMQGEAAQKQGAPGFGM

Gene
tim10
Protein
Mitochondrial import inner membrane translocase subunit tim10
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
93 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
10.103 kDa
Sequence
MSFLFGGAPKMSSEQKIAAAETEVEMITDMFNRLSESCSKKCIPNDYREGDLNKGESVCLDRCVGKFFEVNIKVSEKMQGVAGQQQGGAGLSL

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
93 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. Compared to TIM9, it may function as a substrate sensor.
Similarity
Belongs to the small Tim family.
Mass
10.305 kDa
Sequence
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF

Gene
Tim10
Protein
Mitochondrial import inner membrane translocase subunit Tim10
Organism
Drosophila melanogaster
Length
92 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
10.578 kDa
Sequence
MALPQISTADQAKLQLMQEMEIEMMSDLYNRMTNACHKKCIPPRYSESELGKGEMVCIDRCVAKYLDIHEKIGKKLTAMSMQDEELMKKMSS

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
91 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
10.108 kDa
Sequence
MFGLGGAAPQISSQQKLQAAEAELDMVTGMFNQLVEQCHSKCINKTYNDSEVSKQEALCLDRCVAKYFETNVQVGEHMQKMGQSGQFMGRQ

Gene
tim10
Protein
Mitochondrial import inner membrane translocase subunit tim10
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
90 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Similarity
Belongs to the small Tim family.
Mass
9.923 kDa
Sequence
MFGLGRPQPTSAEKIAAVENELKVVAEMHSRMVKICTLKCIDKSYREGDLSKGESVCLDRCAAKFFETHQKISDQLQKETQARGGGGFGM

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit Tim10
Organism
Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695)
Length
90 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
9.935 kDa
Sequence
MFGLGGAPQISSEQKLQAAEAELDMVTGMFNQLVDQCHSKCINKSYGDSDITKQEALCLDRCVAKYFDTNVQVGEHMQKLGQSGQFMGRK

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
89 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
9.966 kDa
Sequence
MFGLGGQPQLSSQQKIAAAEAELDLVTDMFNKLVSNCHRKCIDMNYNEGDLNKNESNCLDRCVAKYFETNVKVGENMQQLGQNFSPGKF

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
89 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
9.935 kDa
Sequence
MFGLGGQPQLSSQQKLSAAEAELDLVTDMFNKLVDNCHKKCIEQIYNDGQLNKNESTCIDRCVAKYFETNVKVGENMQQLGQAFSPGKF

Gene
tim10
Protein
Mitochondrial import inner membrane translocase subunit tim10
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
89 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
10.195 kDa
Sequence
MSMFGIGKNNQTINPQNIAMAEQEVEMMSDIFNRLVMTCHKKCISPKYYEADLTKGESVCIDRCVSKYFEANQSLSQHMQKRGQENPTP

Gene
TIM10
Protein
Mitochondrial import inner membrane translocase subunit TIM10
Organism
Arabidopsis thaliana
Length
83 amino acids
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Similarity
Belongs to the small Tim family.
Mass
9.339 kDa
Sequence
MASPIPVGVTKEQAFSMAQTEMEYRVELFNKLAQTCFNKCVDKRYKEAELNMGENSCIDRCVSKYWQVNGMVGQLLSAGKPPV