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SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
635 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
74.039 kDa
Sequence
MSANDILDVLNIQRDESNQPPKKKQKSSSTPTLPDGKQLTGMARELYNLVGPNTPPINLNSNSYTANKEKMKKFKPSPWTRMPFTPKQGIELNHWVKGSKELIEQQEFEEDGTPKPYFFEKYNVQLEIPEFVDEDTYDLYMIEIKEYESKMKEERARREKERKEREKRDLEEKKKKQQQQQQKSQQNPQNQIKDDEKNQDTRNNTDKKDSEQKSEDKPTVEAKKETDEKKDDVVLKDNTNETKPVTETTKSETETTEQNNSEKTNENETNKTNDKDGEGNLTKSKDSATEDQSNNKKENDEDTESEWTYKETKHLFELCQAFELKWPIIHDRFPNPNRTAEDLKEQFYRICIKILENQKNKNQALIDSLKAYCKPRELERKQYLENLLKRTPAEIAEEESLVIEARRFEIAAKKMLMERSNLLTLLDSPQTTQNVSQYQSSQGITNLYNNLLIYDKHQKKKQMANKSNPQQEPVPPPIPLAASSSVKRDRGFQTQLQQYLSSFLKQNHHTNPAVKQEINSIQQLLMKRLTQKEEEAYGLYFHGTEKLNPGVMLRSQQKLPGLNQRQSILKSVNILLQEMDIPTGGGTSWKPIMPTRKTMAKYDELIRSVVTLLDVKKAKDKLESEIKLIKSQRGL
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
624 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
69.444 kDa
Sequence
MTSSDVRDVLNLGDGTVGPRSSKKQKLAAPRPNLKGLAREVQNLGGDNPIAIVPEVTHFKKRRFTSRKPTAKWEMRPFKNSARSDSNFTLRHWRRKDEKQEGIDESQEQISQGDQPQPQKNELEDSAFAKYNVQVSVPQYSEGQYQQSLQHVDWTKEETDYLLELAQDFDLRWPLIWDRYEWNPPATNGEADDDGDESKAIVPATRSRTLEDLKARYYEVASKMMAAQKPVQYMTQPEFSLHELMAHFNPQQEKLRKEFALNALTRSREEAREEESLLLEIKRILARSERFNDERRELYNRLDYPRSDTDINAFKSSAGLQNLLQNLVTADKTKKRKSLMPGDVNSPAGTVPPQTAAAASAAATAAAVAQEAGRRESTAASTGPRESTGPAPTPAAANNKKGQQQQQERRKLTTQEELLYGVTHHDRLGSGPTFRTEKINKLFSHKSNQQQMRITNVLNELDVPNKLIMPTAATTHQYEQLLAAVNSLLDARKVSDKLDQEIKTEQAKKAERQKAMAPPEAESTAENGQTGQEKKDGDDGEACAAAVTADTSKEETNGDATSAAGDATKDGLETAVLTSEAPDAPPKETEQNIDERPGSSGAPHKRSASVLSNVSDKSNKRQKK
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
615 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
66.954 kDa
Sequence
MTSNDVRDILSLPERPASQPSSSAQASGSSSRNRKSSGSNNPHPSSAASASRPKPKYDGMTRELFALLGDNAPSLAMTHGLDAEGKPVMGLGGLFKPKFKRRKEKVRQWRWTPFLNSARDDTQIDDDVPEINHGLILHHWAPARSFSTTAADGISAEDADIDTKYQYAAFNTTSGVYSYSNDEYIQHLRDDDWTKEETDYLMELCTAYDLRFVVIHDRYDWAAAQASFLAGSTSAVPQPVKERSMEDLKVRYYAICRRLIRSRISTDDVETRQMLLSTYAFDKQREVERKKAVARLYTRTPEQLAEEEALYVEIRRIEQNEAKYASEREELLRLLGGWESLPSSSPHAVAAAGSGIASLLGAEEDSTAKGRAGSANKKRKLQQIEDNGTPGADDAGSSTGATAAATSRPSANLTSKQRAELRQAQFDEMQCIVRFASNANATTDASAGGIAGPAAVSAASSSTRPPYAYLVGTASTLPAVTSNPANPTSGHGVYLRSSRMLAPRPNLVLRTTQVLSESDPPVGPRLIFPTAKNVEKWENLIGAVTTGLEMRKQLERVNAELRIAKQRIAAALHPNRMADKSEASAEAVESRSAAPTENSIAATTSTHAQITIKTE
Protein
SWR1-complex protein 4: SWC4

Gene
swc4
Protein
SWR1-complex protein 4
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
588 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
65.954 kDa
Sequence
MAAADVRDMLDLPAEGQPRPHKKQKVVEKRPDTDVQASEGITRELYALLGERAPPIAINENRYKGRPKWMSKLRVRPWQMTPFTNNARSDGLVLRHWQRQSESAKAPALEGASEMEVDQAKAGGGAATPEKEYPFAKYNVKPRVPRRYTDEEYNRHLKSDDWSRQETDYLMDLVEEYDLRWVVIADRYDFQPQPIDAEANATALVPAKQYRTMEQMKARYYFIAASMLALEHPPSEMSEAEFDLHEKMMKFDPDRERARKELAALQLNRTADEVREEGILLEELKRITSNEQNFMTERRELYSRLEVPISVGNTTMYQSSQGLSQLLQTLLQADKSKKRRSILGPEAAAPSPAGQTPTSNAPTSARDSRADTPSHASAGPSSKKGSTAAAAKEPPQTVKTLTPAEEARYGVQHHDRLVPGVQFRSDRAQKLTQAKSNVQSQKLATALAELEIPPRLLMPTERVCKEFEKLIHSVNLLLDARKVSEKIESEIRVLEAAREERERKTKEVKDKGKPEVKSEEVENSDSGAGDSASAAPTADERADERADKGLQGAEDPDQSTGDRDGVSHKRSASVLSNGSDKSTKRQKK
Protein
SWR1-complex protein 4: swc4

Gene
swc4
Protein
SWR1-complex protein 4
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
586 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
66.337 kDa
Sequence
MAAADVRDMLDLPAEGQPRPHKKQKVVEKRPEGITRELFALLGERAPPIAINENRYKGRPKWQTKARVRPCARSDDLVLRHWQREPESTNIPAIEDTRAEGETKEQGEHKTADREYPFAKYNIKLKFSNRYTTDEYNRHLRSEDWSREETDYLMDLVEEYDLRWVVIADRYDFQPQRVDNTEETSSALVPSKQFRTMEQMKARYYFVAASMLALEHPPSEMSEAEFDLHERMMKFDPERERHRKELAALQLNRTADEVREETVLLEELKRITANEQEFVTERRELYSRLDVPISVSNATNYHNSQGLSHLLQTLLQADKSKKRRSILGPDGIAPTSGGQTPTIPNAPGSARDSSRADTPNGGTTQSTTTKKAAAAANREAAQQAIRTLTPAEEARYGVQHHDRLAPGVQFRSDRAQKLTQAKSHVQTQKLASALAELEVPLRLFMPTERVVKEFEKLIHSVNLLLDARKVAEKVESEIRVLEAAKEERERKAKELREKDKPEVKSEQQDNDVPIPPAPAPVAAGDASQTGQPAKTNEGQAELNGSSTTNNVADSEPSTQEQEGVSHKRSASVLSNGSDKSSKRQKK
Protein
SWR1-complex protein 4: swc4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
532 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
60.57 kDa
Sequence
MSSSDIFDVLNIKQKSSSPNAASPSVPASGKSSKPQLTGMQRELYNLLGENEAPVVVQSMNRFKEKLASNAKPTPWSLANFKANEYLTLQHWVKGSRELIGEEPQESEFKKYDVHLTIPEFTEDEYNSFIPTSNAEENEKQNIGEKVEANGDSTDVNMTEEDTNDKVKESVPQDENKSTSDNKKNNEKWEYNEVKYLFDLCKKYDLRWFVIQDRYDYENSNRTLEDLKSKFYEVSKCYFKAKKPDDPMLQSLNYSKDKETQRKKYLERLLARSAAEIAEEEALIIESRKFEMAAKKTLAERETLLRLLDSPQSDISVAQYLTSNGMSQLYNSLLADKSRKRKIDSAVPENPWMKQQHQFAQQRQQMQQLQQKKLEKHDASATPGPATTVTATETSTNVTSAGSIPSGLQSPKKTKRQKLELQTALKRKSESEYAEQLLKIFNMDERKSLGVIAHGEKLSPGVFLRSAKITTFKPAIQNKIISTAQELGIPARPVMPTFEVVTEYEALLKKIATLLDIKKQIDKIEAGKQITK
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
504 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
56.599 kDa
Sequence
MASSSDVRDVLDLPDLEPNDKLTQQPKRQKLAAPVGGKRMDGMQRELFALMGENTPSVSVTKDSHTSLFKDKPQWQAKLTPWMWTPFQNQAREDGLILSHWVRGGELTQGDQYPFAALNTQISFPELTQEDYDGLKLATPGWTLEETRYLMHLCSEFDLRWPVIHDRWEWQTDQDVTMATGETKGAEGTESKVKEEDKDVEMADVKEEKENKDESNKEKSEKKESAPPDGTARTVEDLKERFYNVVSAMSKHPEKYTAEGYNMTTVKFPRDMEIKRKQYLERLLARSPAEIAEEEALILKSRKLELSATKMLQERQELLKLLDAPQPTSSVAQFQTSQGLAHLTSTLNDKSKKGGKPTKEGSVGPQAPDRGGSVEKTTKKEDTKEAKKATKEDKKAATTIAAAISKKLTTKEEAAYGISYHDKLTPGVYLRSSKVTTFKPTIQTKIVAALQDIGIPPKPVMPTAKVCAKFESIQHSMSVLLETKRAADKLETEIRLLRGQKGQL
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
497 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
57.908 kDa
Sequence
MSSSDIFDVLNIRPKSSSPDAEAQTPTPSSGTVKHNKPQVTGIQRELYSLLGDNTPTVPIKQGNKFKDSLNSNIKPSPWSFVEFEANSHLKLRHWVKGSKELVGATVEPSSFAKFNQHLTIPSFDEQEFQQFMNGNNSEWKYGEVQYLFDLCRNYDMKWFVIADRFNYNGTERKLDDLKEMFYTVCQWYFLYKDPDNPLISQLNFPKEKELERKKYLERLLKRTAAEIAEEEALIIESRKFEMAAKKTLQEREALLQLLDHPHSDKPISQFLTSQGMSQLYANLLNDKNRKRKPDSNTPENPWMKQQQQFAQQRQQIQHQQQFKQGQIIQQQQQQQQQQQQQQQQKQQKQQKPQSDQITSKDQQPSENIEVKTEGQRLNKKQKIELQNALRRKQDSEYAEHLLEKFTLEERKALGVIAHGEKLAPGVYLRSSKISTYKPAVQNKIVATLQELGLPVRPAMPSLEVVQEHEKLLKKIATLLELKKQVDKLTAEKQIVK
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
488 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
56.132 kDa
Sequence
MSSSDIFDVLNIQPKSSSPHPQTSQSNAGASKTPKPQVTGMQRELYNLLGDNTPPIVIQPTSKFKDRLASLTKPSPWTHTEFEATPYVKLSHWVKGSKELLEGQSPKSSFAKYDQKLTLPEFTEGEYQEFMAQAAKGANSDAPTWSYEEVQYLFDLCRRYDLRWHIVYDRYMYDESRTMEDIREMFYTVCQKYFQAKDPGNPLLPSLAYSKDQEIQRKKYLTRLLSRSAAEIAEEEALIMESRKFEMAAKKTLQEREAMLRLLDHPQGDANVSQFLTSQGMNQLYNNLLNDKQRRRKPDSAPPENPWMKQQQQFAQQKQQLQLQHQQHHQLRDQKRIEVKTDPVTPGSPKQDSPSPGRKASDQSAAPRMNKKQKLEMQTAMRRKQDSEYAQHLLKNFSSEERKSLGVTLHGEKLAPGVFLRSSKISTFKPSIQNKVVSVLQELGLPVRPAMPSAAVVQHHDELLRRIVTLLDLKRQQDKLEAEKAIVK
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
476 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
Similarity
Belongs to the SWC4 family.
Mass
55.213 kDa
Sequence
MSSSDIFDVLNIKQKSRSPTNGQVSVPSSSAANRPKPQVTGMQRELFNLLGENQPPVVIKSGNNFKEKMLSTSKPSPWSFVEFKANNSVTLRHWVKGSKELIGDTPKESPYSKFNQHLSIPSFTKEEYEAFMNENEGTQKSVESEKNHNENFTNEKKDESKNSWSFEEIEYLFNLCKKYDLRWFLIFDRYSYNNSRTLEDLKEKFYYTCRNYFKASDPSNPLLSSLNFSAEKEIERKKYLQRLLSRSAAEIAEEEALVVESKKFEMAAKRTLAERESLLRLLDSPHSDQTITQYLTSQGMSQLYNALLADKTRKRKHDLNIPENPWMKQQQQFAQHRQLQQLNVKKSEVKENLSPKKTKRQRQEMQTALKRKSESAYAEQLLKDFNSDERKALGVITHGEKLSPGVYLRSTKLSTFKPALQNKILAILQELSLPSRPVMPSFDVMERQEELLKKINTLIDLKKHVDKYEAGMSITK
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
463 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
52.154 kDa
Sequence
MSAQDVRSILSLPPSTPLPTLSSSKKVPVPRKPDGITRELYALIGDNAPSLADAQASLAAVKYREKPALKGKKVHWEWTKFTPAARRDNPVRLGHWARITDSDPNDSVEYFGKFNLHGPSVMEYSQFEYDQHLVDPNWTLQETEYLFELLKEYDLRFIVAADRYAYVSPEGEKRKRSVEDMKDRYYTICRRLIRTRTASDPVHQQHLIQAYAFDKAREIKRKQYASDLFHLTPAEIAEEEALYVEITRMQQNERRFRADRDELMRSVMGLDSGLVEVDQSAMENAIGVDKNKKKRKAEDESAAPSPAPTPKKPAPNAGFDNSRCIYHLPTPSNANSLTSHLSQKHPPHQQAFLRGSRLPLPKPTAAGRITDLLAELGLSANRLVMPTRQNMEVFEGLLNAAAALVEMRRQVNRVEQELRVVRMQKEGLMPVTTNPSARVKGEAGVVTGGSEATVKAVTPVKEC
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
463 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
52.154 kDa
Sequence
MSAQDVRSILSLPPSTPLPTLSSSKKVPVPRKPDGITRELYALIGDNAPSLADAQASLAAVKYREKPALKGKKVHWEWTKFTPAARRDNPVRLGHWARITDSDPNDSVEYFGKFNLHGPSVMEYSQFEYDQHLVDPNWTLQETEYLFELLKEYDLRFIVAADRYAYVSPEGEKRKRSVEDMKDRYYTICRRLIRTRTASDPVHQQHLIQAYAFDKAREIKRKQYASDLFHLTPAEIAEEEALYVEITRMQQNERRFRADRDELMRSVMGLDSGLVEVDQSAMENAIGVDKNKKKRKAEDESAAPSPAPTPKKPAPNAGFDNSRCIYHLPTPSNANSLTSHLSQKHPPHQQAFLRGSRLPLPKPTAAGRITDLLAELGLSANRLVMPTRQNMEVFEGLLNAAAALVEMRRQVNRVEQELRVVRMQKEGLMPVTTNPSARVKGEAGVVTGGSEATVKAVTPVKEC
Protein
SWR1-complex protein 4: SWC4

Gene
SWC4
Protein
SWR1-complex protein 4
Organism
Arabidopsis thaliana
Length
441 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.
Similarity
Belongs to the SWC4 family.
Mass
49.824 kDa
Sequence
MGGTDAKDILGLPKTPLSLTQEKKSRPQKESHRKPDGISREVYALTGGVAPLMPSIDLKRRPPADEKVAWKWLSFTNSARKDDLQLYHWVRVVNDVPPTGDYSFAKYNKSVDILKYTDEEYENHLTDSVWTKEETDQLFEFCQNFDLRFVVIADRFPVSRTVEELKDRYYSVNRALLRARAQSPADVANHPLMKEPYDITRDRERKRALSMVLSQSRHQEKKDAEILAEAKRITEMRLAARRAEEPDVSANENAGLDKADGVVPGRSVSPTSNSQLPATAVAPSTLTMADYASTLASLRMLHVYLRTYGLEQMVQAASSAVGLRTIKRVEQTLQDLGVNLKPKVPTKTVCDEHLELRKEILTLLNLQKQLQYKESEGSSHREGSYAAMPDTPKDRVFAPDPFSFGAERPIKKEQKRKGPGRQADTPSPAHKRPRKLKASDL
Protein
SWR1-complex protein 4: SWC4

Gene
swc4
Protein
SWR1-complex protein 4
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
437 amino acids
Function
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).
Similarity
Belongs to the SWC4 family.
Mass
50.384 kDa
Sequence
MTSADIRDVFELPPPEIGNKQKSKTPTERRPEGISRELYSLLGENSAPLAIYQKKFKEKPKVSHKAKNWVRQPFSISSRKDDFTLHHWVLKSEVDSEASYKFEKFNVPLFIIDYTDEEYQNYLKDEDWNKDETDYLFRLCKDYDLRFFVIADRYDNEKYKKHRTLEDLKDRFYSVSRKILLARNPINSMTAAQSSLLNTMEYNKEQEVIRKKYLIGLASRTPEEVAEEEALFIELKRIETSQAKLLSDRDEVLRLLDEQKGDGGIHEYHTSAGMSSLIQDMINSQRTKNKVEEAIVSSSAPSSGVSSVLNTPTRPHALSTPRIRYGPQPTDPQFGITWHEKLHPGTFVRSQKIPAIKASLSQRVSSVMTELGVSSRLIMPTAKNFEKFVELQNSIVSLLELKRKVDRLSQETEIQDKLSRKRSASPDGSESKKHISQ
Protein
SWR1-complex protein 4: swc4