Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).

Belongs to the SWC4 family.

488 amino acids

MSSSDIFDVLNIQPKSSSPHPQTSQSNAGASKTPKPQVTGMQRELYNLLGDNTPPIVIQPTSKFKDRLASLTKPSPWTHTEFEATPYVKLSHWVKGSKELLEGQSPKSSFAKYDQKLTLPEFTEGEYQEFMAQAAKGANSDAPTWSYEEVQYLFDLCRRYDLRWHIVYDRYMYDESRTMEDIREMFYTVCQKYFQAKDPGNPLLPSLAYSKDQEIQRKKYLTRLLSRSAAEIAEEEALIMESRKFEMAAKKTLQEREAMLRLLDHPQGDANVSQFLTSQGMNQLYNNLLNDKQRRRKPDSAPPENPWMKQQQQFAQQKQQLQLQHQQHHQLRDQKRIEVKTDPVTPGSPKQDSPSPGRKASDQSAAPRMNKKQKLEMQTAMRRKQDSEYAQHLLKNFSSEERKSLGVTLHGEKLAPGVFLRSSKISTFKPSIQNKVVSVLQELGLPVRPAMPSAAVVQHHDELLRRIVTLLDLKRQQDKLEAEKAIVK

56.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make SWC4 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here