Protein
Transcription elongation factor spt4
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Function
The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
Similarity
Belongs to the SPT4 family.
Sequence
MSSSYYVTPSQQRTLRACMVCSLVQLHSKFMRDGCPNCDNVLGLRGNNDAIQECTSQVFEGLITLRDPSTSWVARWQRLEGYVAGTYAVKVTGSLPDDVITNLEDSGVRYIPYVYLPGSCVSGDTDRLVGGMAVRWRRRPEVLELSSEVEVQFAWI