SKI

Gene

SKI

Protein

Ski oncogene

Organism

Gallus gallus

Length

750 amino acids

Function

May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. May function in TGF-beta signaling (By similarity).

Similarity

Belongs to the SKI family.

Mass

84.282 kDa

Sequence

METVSRSSFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEMYKKDNGKDPAEPVLHLPPIQPPPVMPGPFFMPSDRSTERCETILEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGTYPPHCKKEFSSTIELELTEKSFKVYHECFGKCKGLLVPELYSNPSAACIQCLDCRLMYPPHKFVVHSHKSLENRTCHWGFDSANWRSYILLSQDYTGKEEKARLGQLLDEMKEKFDYNNKYKRKAPRNRESPRVQLRRTKMFKTMLWDPAGGSAVLQRQPDGNEVPSDPPASKKTKIDDSASQSPASTEKEKQSSWLRSLSSSSNKSIGCVHPRQRLSAFRPWSPAVSANEKELSTHLPALIRDSSFYSYKSFENAVAPNVALAPPAQQKVVSNPPCATVVSRSSEPPSSAAQPRKRKHAAETPAVPEPVATVTAPEEDKESEAEIEVETREEFTSSLSSLSSPSFTSSSSAKDMSSPGMQAPVPVNSSYEVAAHSDSHSSGLEAELEHLRQALDSGLDTKEAKEKFLHEVVKMRVKQEEKLNAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRIRLKRELEQARQIRVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLMHEREAREHLEKVVKELQEQLWPKSSSQSSSENTTSNMEN

Protein

Ski oncogene: SKI

Gene

SKI

Protein

Ski oncogene

Organism

Equus caballus

Length

730 amino acids

Function

May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling (By similarity).

Similarity

Belongs to the SKI family.

Mass

80.394 kDa

Sequence

MEAAAGGRGGFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEAYKKESAKEAGAAAVPAPVPAAAEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHTYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQTRLGRCLDDVKEKFDYGNKYKRRVPRVSSEPPASIRKTDDTPSQHPTSSEKDKQSGWLRTLASPSSKSLGCVHPRQRLSAFRPWSPAVSTSDKELPPHLPALIRDSFYSYKSFETGVAPNVALAPPAQQKVVSSPPCATVVSRAPEPLATCVQPRKRKLAVDTPGAPETPVPVAAPEDDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLSSPGVHVPPVAPAAADAAAPADTPSSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLSAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQARQVRVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRPRSEATGGESTAELEP

Protein

Ski oncogene: SKI

Gene

SKI

Protein

Ski oncogene

Organism

Homo sapiens

Length

728 amino acids

Function

May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.

Similarity

Belongs to the SKI family.

Mass

80.005 kDa

Sequence

MEAAAGGRGCFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEAYKKESAKEAGAAAVPAPVPAATEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYGNKYKRRVPRVSSEPPASIRPKTDDTSSQSPAPSEKDKPSSWLRTLAGSSNKSLGCVHPRQRLSAFRPWSPAVSASEKELSPHLPALIRDSFYSYKSFETAVAPNVALAPPAQQKVVSSPPCAAAVSRAPEPLATCTQPRKRKLTVDTPGAPETLAPVAAPEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLGSPGARALPSAVPDAAAPADAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLSAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQARQARVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRARPEAAGSEGAAELEP

Protein

Ski oncogene: SKI

Gene

Ski

Protein

Ski oncogene

Organism

Mus musculus

Length

725 amino acids

Function

May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.

Similarity

Belongs to the SKI family.

Mass

80.119 kDa

Sequence

MEAAAAGRGGFQQPGLQKTLEQFHLSSMSSLGGPAVSRRAGQEAYKKESAKEAGAATVPAPVPTAAEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHIYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYANKYKRRVPRVSEPPASIRPKTDDTSSQSPASSEKDKQSTWLRTLAGSSNKSLGCTHPRQRLSAFRPWSPAVSASEKETSPHLPALIRDSFYSYKSFETAVAPNVALAPPTQQKVVNSPPCTTVVSRAPEPLTTCIQPRKRKLTLDTAGAPDMLTPVAAAEEDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLSSPGMHAPPVVAPDAAAHVDAPSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLTAALQAKRTLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRVRLKRELEQARQVRVCDKGCEAGRLRAKYSAQVEDLQAKLQHAEADREQLRADLLREREAREHLEKVVRELQEQLRPRPRPEHPGGESNAELGP

Protein

Ski oncogene: Ski

Gene

ski

Protein

Ski oncogene

Organism

Xenopus laevis

Length

717 amino acids

Function

May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. May function in TGF-beta signaling (By similarity).

Similarity

Belongs to the SKI family.

Mass

80.74 kDa

Sequence

METVSRSSFQPHAGLQKTLEQFHLSSMSSLGGPAAFSARWTQDLYKKECGKEPPEPILHLPSQPPPVIPGGPLFMPSDRSTERCETILEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHVYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALMYGGSYPPRCAKKSDFPPGPLELELTEGSFKVYHECFGKCRGLFVPELYGHPSAPCIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLARDGVGGDDELARLGRLLEEIKEKFDYSNKYKRKAARLSSEPVAKKAKADDSIIHSPSSAEKDKSSSWLRNLSNINKNAGYVHPRQRLSAFRPWSPAISANDKELSTHLPALIRDSFYNYKSFENLVAPNVALTPPVQQKVITSPPCVPAVPRSTQSSGSPPQSRKRRPTAELPIVPEAPAPPVPIREEEKESETEIEVESREECTFTSSLSSLSSPSFTSSSSAKELSSPGMLAPTVINTSYEVASHNDQHCSGLEAELEHLKQALDSGLDSKEAKEKFLHEVVKMRVKQEEKLNAALQAKRSLQQELEFLRVAKKEKLREATEAKRNLRKEIERLRAEHEKKMKEANESRLRLKRELEQARQIRVCDKGCEAGRIRVKYSAQIEELQSKLQHAENDREQLRTDLVHEREAREHLEKVVKDLQEQLWSKTSHLPSSEHTRKDIEN

Protein

Ski oncogene: ski