May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling (By similarity).

Belongs to the SKI family.

730 amino acids

MEAAAGGRGGFQPHPGLQKTLEQFHLSSMSSLGGPAAFSARWAQEAYKKESAKEAGAAAVPAPVPAAAEPPPVLHLPAIQPPPPVLPGPFFMPSDRSTERCETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINSVCDELHTYCSRCTADQLEILKVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVYHECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSANWRAYILLSQDYTGKEEQTRLGRCLDDVKEKFDYGNKYKRRVPRVSSEPPASIRKTDDTPSQHPTSSEKDKQSGWLRTLASPSSKSLGCVHPRQRLSAFRPWSPAVSTSDKELPPHLPALIRDSFYSYKSFETGVAPNVALAPPAQQKVVSSPPCATVVSRAPEPLATCVQPRKRKLAVDTPGAPETPVPVAAPEDDKDSEAEVEVESREEFTSSLSSLSSPSFTSSSSAKDLSSPGVHVPPVAPAAADAAAPADTPSSGLEAELEHLRQALEGGLDTKEAKEKFLHEVVKMRVKQEEKLSAALQAKRSLHQELEFLRVAKKEKLREATEAKRNLRKEIERLRAENEKKMKEANESRLRLKRELEQARQVRVCDKGCEAGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRPRSEATGGESTAELEP

80.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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