SAC3A

SAC3 family protein A

1006 amino acids

Component of the TREX-2 complex (transcription and export complex 2), a muliprotein complex that functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (PubMed:19843313).

Belongs to the SAC3 family.

111.26 kDa

MNHGGNTQAVAPMDPNSIENRYGVDGSQTQKYSYQYSTGSESAPWTGHSVENQAVENGNYSNSNYYHPQPTGPATGNVQEIPNTVSFTISSTSGTANVAQDYSGYTPYQTSSDPHNYSNTGYSNYYSGYQQQPSQSYPQPVGAYQNTGAPQPLSSFQNPGSYAGTPSYSGTYYNPADYQTAGGYQSTNYNNQTAGSYPSTNYSNQTPASNQGNYTDYTSNPYQNYTPDAANTHSSTIATTPPVHYQQNYQQWTEYYSQTEVPCAPGTEKLSTPTTSAYSQSFPVPGVTSEMPASNSQPAPSYVQPWRPETDSSHPPSQQPGAAVSTSNDTYWMHQAPSLQAHHPVPPQNNYQSPLETKPLYETPFQGHQRATYPQEMNSQSSFHQAPLGYRQPTQTAPLVDSQRVSKVQIPTNPRIASNLPSGFTKMDKDSTAASAAQAPAYVSVSMPKPKDHTTAMSDPGTFPKSLRGFVERAFARCKDDKEKESCEVALRKIVKKAKEDNTLYTRDWDTEPLSTVTTTNVTNSESSSAQLSSLQNKSPTRRPKSRWEPLVEGKPFVKPASTFSSAVKFGVWNHQNENNKKSSESFQKVDAATGFKPTYSGQNSAKKSFQRPVKRQRFSGGAATAIDDEASSDSDKDLTPYYSSAMALAGSAEEKKRRDSRSKRFEKIQGHSRGNDLTKPKNANVGNLHSRRATALRLSKVFDESGSRAVEDIDWDALTVKGTCQEIEKRYLRLTSAPDPATVRPEDVLEKALIMVQDSQKNYLFKCDQLKSIRQDLTVQRIHNHLTAKVYETHARLALEAGDLPEYNQCLSQLKTLYAEGVEGCSLEFAAYSLLYITLHSNNNRELLSSMSRLSEEDKKDEAVRHALSVRAAVTSGNYVMFFRLYKTAPNMNSCLMDLYVEKMRYKAVNFMSRSCRPTIPVSYIVQVLGFTGAASEGTDEKETDGMEDCLEWLKTHGANIITDSNGDMLLDTKATSTSLFMPEPEDAVAHGDRNLDVNDFFTRT