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Ripply3

Gene
RIPPLY3
Protein
Protein ripply3
Organism
Homo sapiens
Length
190 amino acids
Function
Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives (By similarity).
Similarity
Belongs to the ripply family.
Mass
20.368 kDa
Sequence
MEPEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVSSRGGKCSSSK

Gene
ripply3
Protein
Protein ripply3
Organism
Xenopus laevis
Length
170 amino acids
Function
Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of tbx1 that plays a key role in pharyngeal development. Plays a role in the formation of the anteroposterior (AP) axis during embryonic development; required to establish the posterolateral border of the pre-placodal ectoderm (PPE) acting downstream of the retinoic acid receptor (RAR) signaling.
Similarity
Belongs to the ripply family.
Mass
18.941 kDa
Sequence
MDSSQYMLKATLTQMCLCSRGVRNVHSEHPQQQDSSLTLWRPWLLGAGDRELDGQQRRSGEADGVPTNTGPKGALGFQHPVRLYMPKSKTSEYLQHMGRKVLASFPVQATIHFYNDDSDSEEEDEEEEMEFYNYYQNCAANGVDSSRGSSDNYSVQGGPKRNIGSHAGSA

Gene
Ripply3
Protein
Protein ripply3
Organism
Mus musculus
Length
152 amino acids
Function
Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives.
Similarity
Belongs to the ripply family.
Mass
16.965 kDa
Sequence
MRPEAAGVREARGRLCHCPGDDPGRLPLPRGPESSIPAPWRPWMSPPPGDAELTRTERPCESWGDQHTSGSKGAFGFQHPVRLYLPVSKRQEYLQSSGEKVLASFPVQATIHFYNDDSESGSEEEQEEEAQPNHLQCLEAEVRDSAQEERAE

Gene
ripply3
Protein
Protein ripply3
Organism
Danio rerio
Length
110 amino acids
Function
Probable transcriptional regulator involved in developmental processes.
Similarity
Belongs to the ripply family.
Mass
12.477 kDa
Sequence
MLPVCVDADQALRCSVLWRPWSLSPTEARGHKTLAGGVRSARPSGGVFHHPVRLFLPRSRMQEYLSRLGSSVLASFPVQATLHFYNDEDSSSEEEEDEEHANTRCRLWRP