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RPH3AL

Gene
RPH3AL
Protein
Rab effector Noc2
Organism
Homo sapiens
Length
315 amino acids
Function
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells.
Mass
34.464 kDa
Sequence
MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRKQHLSPAEVEAILQVIQRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTGVRDRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGPRPGLTRRAPVKDTPGRAPAADAAPAGPSSCLG

Gene
Rph3al
Protein
Rab effector Noc2
Organism
Mus musculus
Length
302 amino acids
Function
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine cells through interaction with RAB27A. Acts as a potential RAB3B effector protein in epithelial cells.
Mass
33.259 kDa
Sequence
MADTIFSSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRSQCLSPGELEIILQVIQRAERLDILEQQRIGRLVERLETMQRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPVEPTETQPPSAETSRVYTWARGRVVSSDSDSDSDLSSSSLEDRPLPSGVKGTKGDKPRGDSGASMESPRLGPARPPSHLSGSQSSLGSEAGTGATEPQGGTPAQPEPRVPGKRHTWATPRY

Gene
Rph3al
Protein
Rab effector Noc2
Organism
Rattus norvegicus
Length
302 amino acids
Function
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Regulates the exocytosis of dense-core vesicles in neuroendocrine cells through interaction with RAB27A. Acts as a potential RAB3B effector protein in epithelial cells.
Mass
33.433 kDa
Sequence
MADTIFSSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRTQCLSPGEVEVILQVIQRAERLDILEQQRIGRLVERLETMQKNVMGNGVSQCLLCGEMLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPVEPTEPQPQSAEVSRVYTWARGRVVSSDSDSDSDLSSSSLEDRPMPSGIKGTKYDKPRGDSGGSMESPRMGPARPPSHLSGSQSSLGSETGAGATDPQGGTLPRPEPRVSGKRHTWATTHY

Gene
RPH3AL
Protein
Rab effector Noc2
Organism
Bos taurus
Length
292 amino acids
Function
Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells.
Mass
32.043 kDa
Sequence
MADTIFGSGCDQWVCPNDRQLALRAKLHTGWSVHTYQTEKQRKSQSLSPAEVEAILQVIQRAERLDILEQQRVGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKVCTKCGIEASPSQKRPLWLCKICSEQREVWKRSGAWFYKGIPKFILPLKIPGQADHPSFRPLPVEPAEQEPRSTETSRVYTWARGRVVSSDSDSDSDLSSSSLDDRLRPAGVRDPKGNKPWGESGGSVESLKMGPTRPASCLSGSQSSLASETGTGSADPQGGPRTLAGPRGPR