Organism
Rattus norvegicus
Function
Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro) (By similarity).
Similarity
Belongs to the pirin family.
Sequence
MASSKKVTLSVLSREQSEGVGARVRRSIGGPELKMLDPFLLFDEFKGGRPGGFPDHPHRGFETVSYLLEGGSMAHEDFCGHVGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNLKRSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDQGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHRTAVLGEGDTVQLENKDPKRSHFVLIAGEPLREPVVQHGPFVMNTNEEISEAILDFRNAKNGFEGAKTWKSKIGNQ