P2RY2

Gene

P2RY2

Protein

P2Y purinoceptor 2

Organism

Homo sapiens

Length

377 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

42.273 kDa

Sequence

MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL

Protein

P2Y purinoceptor 2: P2RY2

Gene

P2ry2

Protein

P2Y purinoceptor 2

Organism

Rattus norvegicus

Length

374 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

42.137 kDa

Sequence

MAAGLDSWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYAQGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLSWGHARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSIILVCYVLMARRLLKPAYGTTGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPATEPTPSPQARRKLGLHRPNRTDTVRKDLSISSDDSRRTESTPAGSETKDIRL

Protein

P2Y purinoceptor 2: P2ry2

Gene

P2ry2

Protein

P2Y purinoceptor 2

Organism

Mus musculus

Length

373 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

42.175 kDa

Sequence

MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL

Protein

P2Y purinoceptor 2: P2ry2

Gene

P2RY2

Protein

P2Y purinoceptor 2

Organism

Sus scrofa

Length

373 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP > ATP.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

41.651 kDa

Sequence

MATGPDLWNGTVNGTSDGDDWGYRCRFHEDFKYVLLPLSYGVVCVLGLSLNAGALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTALCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGHARYARRVAAAVWGLVLACQAPALYFITTTAQGGRITCHDTSAPELFSHFVAYSLVMLSVLFAAPFAVILVCYALMARRLLRPAYGTAGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRTLDLSCHTLDAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTDATPTAQACRRLGLRRSHGTDTKRTEDSASSEDSRRTEITPARGEDIRL

Protein

P2Y purinoceptor 2: P2RY2

Gene

P2RY2

Protein

P2Y purinoceptor 2

Organism

Cricetulus griseus

Length

166 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

18.792 kDa

Fragment

single

Sequence

VHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLSLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFTLCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPL

Protein

P2Y purinoceptor 2: P2RY2

Gene

P2RY2

Protein

P2Y purinoceptor 2

Organism

Bos taurus

Length

133 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

15.006 kDa

Fragment

single

Sequence

ISVHRCLGVLRPLHSLRWGRARYARRVAFAVWVLVLYCQAPVLYFVTTSTRSSRIICHDTSARELFSHFVAYSSVMLSLLFAAPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAIVLTVFVLCFL

Protein

P2Y purinoceptor 2: P2RY2

Gene

P2RY2

Protein

P2Y purinoceptor 2

Organism

Meriones unguiculatus

Length

82 amino acids

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by UDP.

Similarity

Belongs to the G-protein coupled receptor 1 family.

Mass

9.365 kDa

Fragment

single

Sequence

LPLSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYAQGDHWPFSTVLCKLVRFLFYTNL

Protein

P2Y purinoceptor 2: P2RY2