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Nelf-E

Gene
Nelf-E
Protein
Negative elongation factor E
Organism
Drosophila virilis
Length
281 amino acids
Function
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing (By similarity).
Similarity
Belongs to the RRM NELF-E family.
Mass
31.858 kDa
Sequence
MVYIHFPNNLTEEEHMLQAKYQKLKKKKKALQAHKAPKQEPESALTLKRPTDARDAREVARKLIKSGAIPAIQKQQTKQDQTSFKRPKGQERAKRSTSETTVAAYQPFSSTQNDVAQETIISEIIKEEPRRQNLYQHFATERVREERGLTEKVTLDTTQPEKPRAGNTIFVSGNKVTEEFLKKTFNDYGTIVNVSMEIEKSRGFVSFAKPESADRAIAEMHGKSVTGIVLQVQLARRQPQIVPINDASSSAVWSSIAASKSQKGSHKDLRQMVQYNDDFLM

Gene
Nelf-E
Protein
Negative elongation factor E
Organism
Drosophila melanogaster
Length
280 amino acids
Function
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing.
Similarity
Belongs to the RRM NELF-E family.
Mass
31.811 kDa
Sequence
MVYIHFPNNLTEEEQMLQAKYQKLKKKKKALQAHKAPKPEPESSLTLKRPTDARDAREVARKLIKSGAIPAIQKQTKQDQTSFKRPKGQERAKRSTSETTVASYQPFSSTQNDVAQETIISEIIKEEPRRQNLYQHFATERDREERGMPEKVPMDTAQPEKPRAGNTIFVSGNKVTEDFLKKTFNDYGTIVNVSMEIEKSRGFVSFAKPESADRAIAEIHGKNVNGINLQVQLARRQPQIEPINDASSSAVWSSIAASKSQKGSHKDHREMVQYDEDFLL