Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex, causes transcriptional pausing (By similarity).

Belongs to the RRM NELF-E family.

281 amino acids

MVYIHFPNNLTEEEHMLQAKYQKLKKKKKALQAHKAPKQEPESALTLKRPTDARDAREVARKLIKSGAIPAIQKQQTKQDQTSFKRPKGQERAKRSTSETTVAAYQPFSSTQNDVAQETIISEIIKEEPRRQNLYQHFATERVREERGLTEKVTLDTTQPEKPRAGNTIFVSGNKVTEEFLKKTFNDYGTIVNVSMEIEKSRGFVSFAKPESADRAIAEMHGKSVTGIVLQVQLARRQPQIVPINDASSSAVWSSIAASKSQKGSHKDLRQMVQYNDDFLM

31.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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