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NUT2

Gene
nut2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
253 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
26.752 kDa
Sequence
MAPVTATHQEAQESVKNVIQDLLNLMVQVSQYDTNPSSSNNNTPTSSRASGGGGGGGGGHASSRDIIAQSLQTLDASLLSVYRTANLLPSSPSSGPSNNQPQQGTTELERAEAAQFASTFNNTHNPYAPHVHQPGPQNPGIPIPLITYVENGRNPDVYTREFIELVRRSNQLMRGKMHAFRDFRDVLAGEMEAALPELREDIKRVVEATGGPGPAEGSEERAREGVVGSLSAGGEGQQGQGQGQQGQGQQSGQ

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
199 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
22.051 kDa
Sequence
MGSVKSSNPALEGLHEELGVMEEQIRSIIESFIELGVSVYDFPGTPEASQGMVTNLKRNVDRIFKLNQTSNDPQSALKDVNVPLEVVQYIEDGRNPDIYTREFVEAIRRSNQYQRAKMHGMGMLRDSLAEKIKEQFPELKDDVENIVQRTNMKPTGQARVNSGTTNMTTTAEQSNVVNATAGDVGTNANTTESVEQNGI

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
197 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
20.983 kDa
Sequence
MSSTAGTRRPRQITPTSPSPSPEPQPGATNGSSSTINVAVPSASAPAQVAPSQVAAAAATPVDAAEAVRINLETRVRSVVDLLYQLAVCSADVQEGSQHLVANKVNECIQALAALDATKDELHRAHMMIPQDVLEMLDTGKNPDIHTRNFVNRLASENQYSYGQHRAVERYKATLDAALDQAFPELKAAQAESTETK

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
170 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
18.701 kDa
Sequence
MTTGALPSTPANEPLIKSADNVANLIESFIELGVLVHDNQGTPQSNQALMNKLNQLISQLSQTSTTANDPNDANTNLKQFLIPIDVISYIEDGRNPDIYTREFIEVNAKSNARLKGKMLGFKKLRDVFGDKLKQEFPQLEKGVDDIINRTNDNSSHTASVITDTANNNNS

Gene
nut2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Length
167 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
18.713 kDa
Sequence
MAPITLSTVDDDLKEVIQHLFEIQSAVHGYLGPETQTELVRKIKNLTLALSTLSTHTKPQPPSQDEEQKEKQDDTPEGSANDPLLRDIQLPPEIIDYVDAARNPDIYTREFVELVQRGNQDLKGKKEAFASFRDVLAREMRSAMPECRGEVERVLAATGGARVDTEQ

Gene
nut2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
167 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
18.522 kDa
Sequence
MAPVTLSTVDDDLKEVIQHLFEIQSAVHGYLGPETQQELVRKIKNLTLALSTLSTHTKPHPPPPPPPQPTDPTTAAAPALRDNPDPPLSSIQLPPEIIDYVDAARNPDIYTREFVELVQRGNQDLKGKKEAFASFRDVLAREMRSAMPECRGEVERVLEGTGGKRER

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
Length
167 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
18.297 kDa
Sequence
MAPINPDLQNVQDDIKNVIQDLFQVLVQVSNYDAAGRPTRDVLAQDIQTLDKTLHTLHTNAQHLPTPTADKPIPEPLIQYVENGRNPDIYTREFAELVRRMNQLARGKMHAFRDFRDVLAREMESALPELRADVQMVVGATGGRTVGGEGEGAGQGEGGEGRGEGGN

Gene
nut2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
165 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
18.452 kDa
Sequence
MAPITLSTIDGKLKDIIQHLFEIQSAVHGYLGPETQQELVRKIKNLTTALQTLSLHTRDDPTASTTAPNQYQSTNPNDPALHSIALPPEIIDYVDAARNPDIYTREFVELVQRGNQDLKGKKEAFADFRDVLAREMRSAMPELRGEVDKVIQATGGKKQSERERG

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Coccidioides immitis (strain RS)
Length
163 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
17.69 kDa
Sequence
MAPITLSQIDEDLKDVIQTFFEIQSAVHGYLGPETQQELVKKLKSLTVSLQTLSAHAAPDPSYVQSPPSRTGLSPADPPVQSIQLPPEIIDYVDAARNPDIYTREFVELVQKSNQELKGKMEAFASFRDVLAKEMASAMPECKKEVERVVKATGGSVDGGGCG

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
161 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
18.583 kDa
Sequence
MVEQNLEKLQTDLVETEQRLAAIIDSFIELGVYVYDFPGTEDSMQGMVTNMQRNVDRMKQLNQQANDPESQLQNFLVPLDVLQYIEDGRNPDVYTREFVEAIRRSNQYQRAKIHGLNKLRDSLAEKIIDELPELQPHVESIIARTSPQRTDPISPSIVDKP

Gene
nut2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
159 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
17.714 kDa
Sequence
MAPVTLSTVDDDLKEVIQHLFEIQSAVHGYLGPETQTELVRKIKNLTLALSTLSTHTKPQPPSQDDEQKGSANDPLLRDIQLPPEIIDYVDAARNPDIYTREFVELVQRGNQDLKGKKEAFASFRDVLAREMRSAMPECRGEVERVLAATGGARADTEQ

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
157 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
17.908 kDa
Sequence
MNGNSTNNEQLQQELATTQDQVASIIESFVELGVSIYDFPGTPEATKGMITNLQRNVDRLYKLNVRSNDPQSSLSKVDIPLEVVQYIEDGRNPDIYTREFVEAIRRSNQYQRGKMHGLKQLRDSLADKIVDEFPELKEPVEDIIKRTSPIDNVSNTH

Gene
nut2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Length
155 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
17.042 kDa
Sequence
MAPVTLSTVDTDLKDVIQHLFEIQSAVHGYLGPETQQELVRKIKNLTLALSTLSSHTQSHAPDADTAQANPSDPPISTIELPPEIIDYVDAARNPDIYTREFVELVQRGNQDLKGKKEAFAGFRDVLAREMRSAMPECRGEVDRVVRATGGGEES

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
151 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
17.37 kDa
Sequence
MDQQDLNKLQTNLSDAEIRLASIIESFIELGVSVYDFPGTQESTQGMVTNLKRNVERIKLLNQHANDPDSQLRNMNIPLEVLQYIEDGRNPDVYTREFVEAIRRSNQYQRAKMHALKKLRDSLAEKIGEEFPDLVPQVQGIIERANGSRDK

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
147 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
16.149 kDa
Sequence
MTTATIDSSSGNGPLVSTTEQLQGLIESFIELGVLVHDNQGTQQSHTALTHKTNQVISQLSSLTDSGFTHQYPIPVDVISYIEDGRNPDVYTREFVEVTAKSNARLKGKMLGFQKLRDVLGDKLGKEFPELGSAIEDIKKRTTPDEE

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
146 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
16.324 kDa
Sequence
MTTSTIEQKDENEPLLATADQVSALIESFIELGVLVHDNQGTQQSHTALTHKTNQVISQLSGLTSSPFTHQFPIPVDVISYIEDGRNPDIYTREFIEVTAKSNARLKGKMKAFARLRDVLGEKLGNEFPRLVDSIDDIKKRTTPEE

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
143 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
16.262 kDa
Sequence
MAEAARQELENQLRQTIETLVEISLLVHDTTGSQENKEGLIEQMDTLVKEFQRLKEIKCDKQIPIDVIDYIDQGRNPDVYTREFVELLLKQNQFIHGKMDIYTVSKGVRESTSDDIPLDISCGAHSNTEISTNPGQKRQGNVS

Gene
NUT2
Protein
Mediator of RNA polymerase II transcription subunit 10
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
133 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 10 family.
Mass
14.842 kDa
Sequence
MSTEASTGETPEFQSYDHRGSPTQEAMKREIQSLIQNLVKLSRTAPAIHVLIPPEIVMYVEGSRNPDIYNREFVETVQRMNQMLKGRSEALQALQAQIAHQLQIAIPEMKDDIERAVEATGGKVPITGITLDP