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NTAQ1

Gene
NTAQ1
Protein
Protein N-terminal glutamine amidohydrolase
Organism
Arabidopsis thaliana
Length
221 amino acids
Function
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation (PubMed:30117535). Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule (PubMed:30117535). Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position (PubMed:30117535). Involved in immune response (PubMed:30117535). Controls the expression of specific defense-response genes, activates the synthesis pathway for the phytoalexin camalexin, and influences basal resistance to the hemibiotroph pathogen Pseudomonas syringae pv tomato (Pst) (PubMed:30117535).
Similarity
Belongs to the NTAQ1 family.
Mass
24.972 kDa
Sequence
MSGVTSEPIAMDATRFQHTPYYCEENVYLLCKTLCENGVAEATCSDLFVVFISNEKKQVPLWHQKASTRADGVVLWDYHVICVQRKKESDSEPLVWDLDSTLPFPSPLASYVTETIQPSFQLFAEYQRFFRIVHAPLFFKHFASDRRHMKEPDGSWTAQPPPYEPIVAQDGILHNLSEYIAMSGADTLSSLDPETVTAAISQKLGVVVSHTQLQDLFTKLP