NDC80

Probable kinetochore protein NDC80

788 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

92.45 kDa

MSQTSNPIYGLRRNNGFAGGSNPSNNNNNNSNNNHNGNRISLGSATRTSSIISNNLPFRQSLLHGNYDNAINNTPSTSSLQKQSQQQQQSSQTSQTKRRSTLLSTPATTTKRRQSMMGNNLHQQHQYGSTALRHSTQPSSSMNSQFNQALQHVSPYYNPTSYSSQTPSSQPSSQQYQQQQQQANIPSSASSSQQQQSMDPRPLKDKKYQELIQKEIIRYLIDYKFEIKTNIALTENILKSPTQKNFNAIFKFLYNQLDPNYMFIKSSIEQEIVTLLKLLNYPYMHTITRSHFSAVGGNNWPTFLGILYWLVELNLSLSTLNDDDFLADDDFDKIFIEYIWKSYSLFINDEEEEEQQQQEQQQQANNGGSGGGGGDKFYNDMKIKFDQLQEKLNQELNNVEQQHENLLNKYHELNNQLKIRDDALKKTVALEEDYMKLKSYNQNVEKMMPEWNKKLEQLSNEVISYEEQMNKLQDEKKSIEMDLQQRGISIDKVNELYIKRDQLSKSIEIISNKIDDLKEKLSGRSFDLEKNFDNLENLTNQYNEITNKFNYYYYQQIQQNQQQDQQQQEEEEEEEEEEEHQLIPQFGLKLDENIKTTNERRQFTRDEIFLNINVKQERQNLLNFRNELDHQILNDRSQAMKFNEKCDIEQDKIKDQQSIIEELKIQDSLMKRKSDDLKQTIFQIQNEFNSQIESLDQQIRETKSNIQSDILQLERKLRDVNLNKSLIQEQLIGKRQKIDEDVINLTSFILKFKTNIQEKLINIADIVQDQLKKEQQQQQQQQASQQLE

ndc80

Probable kinetochore protein ndc80

738 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

84.067 kDa

MSQDTGLFSIKRPRETLGSVQNFSSLPQPSSALKRTSSIGYQNPPFTSQHTRSMSLLNSVGRPQQPNFQRSSSGGFGADPGLSSVRRSVSSNVFHGTSAGRPSFAPGSMSSNPASQSLQRRSSVFSRPSTGGAMGHQSFFTQVPSAAGVPRDPRPLRDRSFQARIAQELLEYLTHNNFELEMKHSLGQNTLRSPTQKDFNYIFQWLYHRIDPGYRFQKAMDAEVPPILKQLRYPYEKGITKSQIAAVGGQNWPTFLGMLHWLMELAQMMDRFAMGEYDEACAEMGVDVSGDRIIFRFLTGAYHDWLQGGEEEDDDAAAQRLIPHIELMAQEFEKGNEKYVQEMQVLDAENRALRDQIEELEKNAPDMAKLDKQFRILEDDKRKFEDYIQNVQGKIEKYESRIAFLEDEIRKTESELQAAEEERAGLQASVDQQGLTIQDIDRMNTERDRLQRSLDDAVSRLEETHARVMAKESEASAKLEDLEELVKTYNTLGYQNSLIPSTAVNANGQEYELGLNVNERSFSTSQIGGIPSRISPEADRLLAEPFTGYHPAHLLNLDLRGIVRSNLQALRKEINERRKRGIDADLERRNLLDNIKEAMDEKRSEVEALEHKRRTAEEEFERLKEVTTTQKLASDAQIEKMEKELAKMRATMSESVQLMEQREMNTNIEYEQLTLRANALREELHTNVESMLNDVIRFKVHIQKGLEDYENFVVDEVEQELGGDTQLDEDAPMSTEEL

ndc80

Probable kinetochore protein ndc80

736 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

83.995 kDa

MRSDGLRLTNIFLIQTLGSVQNYSALPQPSSALKRTSSIGYQNPPFTSQHTRSMSLLNSASRPQQPNFQRSSSGGAFGADAGLSSVRRSVSSNIFHGASVGRPSYAPGSLSASSASQSLQRRSSVFSRPSVGGPMGHQSFFTQVPNAAGVPRDPRPLRDRSFQARIGQELLEYLTHNNFELEMKHSLGQNTLRSPTQKDFNYIFQFLYHRIDPGYRFQKSMDAEVPPILKQLRYPFEKGITKSQIAAVGGQNWPTFLGMLHWLMQLAQMMDRFVLGEYDEACAEMGVDVSGDRIIFRFLTGAYHDWLQGGEDEDDETAEKRLVPHIESMAQEFERGNEKYMQEMQVLEAENRALRDQIEELEKNAPDMAKLDKHFRILEDDKRKFEDYNQNVQGKIEKYENRIKFLEEEIQKVEAELQAAEEERSSLQSSVDQQGITIQDIDRMNTERDRLQKSLEDTTARLEETHARVMEKEAEASRKLEDLEEIVKVYNTLGYQTSLIPSTAVNAKGQDYELSLNINDNSFSASQIGGLPNRISSEADRLLAEPFTGYHPAHLLNLDLRGMVRSSLQALRKEINERRKRAIDDDLERRNLLDNIKEAMDEKRSEVEALEHKRRAAEEEFERLKEITTTQKLASDAQIEKMEKELAKMRATLSESVQLMEQREMNTNIEYEQLTLRANALREELHTNVESMLNDVIRFKVHIQKGLEDYESFVVDEVEQELGGDLPATKDVTSQT

ndc80

Probable kinetochore protein ndc80

736 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

83.6 kDa

MSQDTGLFSIKRPRESLAHFSALPQPSSALKRTSSIGAFGNPPTAQHTRMSLLNSASRPQQPNFQRSSSGGAFGADAGLSSVRRSVSSNIFHGASAGRQSYAPGSFSSNPASQNLQRRSSVFSRPSAGVGGAMGHQSFFTQVPNAAGVPRDPRPLRDRSFQARIGQELLEYLTHNNFELEMKHTLGQNTLRSPTQKDFNYIFQWLYHRIDPGYRFQKSMDAEVPPILKQLRYPYEKGITKSQIAAVGGQNWPTFLGMLHWLMQLAQMMDRFIMGEYDEACAEAGVDVSGDRIIFRFLTGAYHDWLQGGEDEDDETAGQRLVPHIEMMAQEFERGNEKYVQEVQALEAENRALRDQIEEMEKSAPDMAKLDKHFRILEDDKRKFEDYNQNVQGKIEKYENRIKFLEDELQKTEADLQAAEDERAGLQSSVDRQGITIQDIDRMNTERDRLQKILDDTMGRLEETHSRVMEKEKEASEKLEALEEVVKAYNTLGYQTSLIPSSAVNAKGQDYELSLNVNESNFSASQIGSAPSRISPEGDRLLAEPFTGYHPAHLLSLDLRGTVRSSLQTLRKDINERRKRAADDDLDRRNLLDNIKEAMDEKRSEVEALEHRRRAAEEEFERTKEITTTQKLASDAQIEKMEKELAKMRATMSESVQLMEQREMNTNIEYEQLTLRANALREELHTNVESMLNDVIRFKVHVQKGLEDYEGFVVDEVEQELGGDMVPADDIPPEEEL

NDC80

Probable kinetochore protein NDC80

726 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

82.885 kDa

MSQDTGLWSVRRPRETLGGISANSAIPQPGSTMKRSSSNIGGNYPGSHVRSMSGSRHSLAMPRPSQPMFQRSSSGTNLVDLGLSSVKRSSFAPKSTFTPGTATKRASTDGDRRSSVYRPRQSTVPAVSHHQSFFQTTPAPAGVPRDPRPLKDRSFQARIGQEIMEYMVQHNFEMEMKHVLSQNVLKSPTQKDFNYMFQWLYHRIDPSHKFQKNIDQEVPPLLKQMRYPFERSITKSQIAAVGGQNWSTFLGLLHWMMQLAQMLDGYVNCQYDEACMEAGIDVSGDRIIFDFLSNGYRDWLAMDEDLGDEEAERVLAPHVQSMAAAFERSNSKYTSELDMLEAENARLLKEIEDLEKSTPDPAVLDHHFKIMEEDKVKFEEYNALAMQRSEKYESRSQVLQEELDKLLEELQEADEERRSLQKAVDAQGISMQDIDRMTAERERLQRGIESASQRLEEVKKKVSEREAEASRKLDELEQMVDRYNTMAYQIALIPSTAANAKGREFELQVTVADDSDFTTSIMKSGPSSADRLVVDSTTGHQAGHILNLDLRGKIRNSFISLRKEISDRRATAMDEMIKDHDLLDGIKEAIEDRRGEVEALNHRVRAAEEEYEKTKEVTTAQKLASDAHIEKMEKELSRMRAGLSENVQILEQREINTTIEYEQLVLQANALREELHTEIDRMLNDVIKFKIHVQKSLDDYEGFVTEELEKELGSDEMQEDTQRMDM

NDC80

Probable kinetochore protein NDC80

706 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

81.821 kDa

MPNEQSEASVLSRLNPHRFTTQIPQHPLSQNMQRRRNSVSSAASDSINSLKQSSARAVSNSNGIQKNNKKYMRSTVAGASGILPTYNKSMSFSQNKNLDDNNMRASLPVLERDLNANNFKSANNNPIGFSSFSQPYSGSRDPRPLRDKNFQSAIQQEIFDYLIQNTFEIDTNYPISLKTLKQPTQKSFVTIFKWLYLRLDPGYTFTKSIEYEVYQLLKILQYPYLESINKSQISAVGGSGWPKFLGMLHWLVTINLRLDKCLNTLDQNLLNQQTQDLTTLSKPVENIEDQEVRQEKYELMAERLFIDYITDSYKTFLNLKDDYSDHMNELKAGFERYLHIIKLDVNNIQSKNENMFEKFEISRNRVEKLKVARGKSTALNGDLVKFQKYVDSMKAKSEEWPIKLSKIEDELNEKKENIKLITEEISQIQDSLQRKGLSVEQIENKNEQKLQLEKEIDQIAEKADEFVSLIKSTKVDNEKVFVTFQDSIRQYNDLLLEFLTSRRKLGHDIEIEPLKITLPNEVVVPNSENALTMDKLFPTDHPMPEYYQNMLLSINSDIMKRIETLKTDNQELEREIGMLTEEINSRGSTNESLELKLSDLNLNLKNVRQENRAEILAQSLEIEKLERQITEGNKNIEQKIANAERIVTELLNEKEVLYNEHSKFKSDLNLKIQKLIKEAHSLRFAVKDSTNRLNELIFTESSETDD

NDC80

Probable kinetochore protein NDC80

703 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

78.513 kDa

MDFRRQTLVSNGGSSQPQPSVPSSAIKKASRLGPARQSLAPSQIQSRTSILGVSNSQENASHGMMGSRKSTVPGKMGDRDQLMSASRGDGGIYGRTPQMNRGIPGSVRRSSVFTSNSQGRTSMAPGVYSTAYKDPRPLRDKVFQSNCMRNVNEYLISVRYPLPLTAKTLTSPTAKEFQSIFKFLVNDLVDPGAAWGKKFEDDTLSILKDLKYPGMDSVSKTALTAPGAPQSWPNMLAMLNWLVDLCKALDNWDDPEIISDPLMVPATELPLDYPNLDDRLLWDFAAKTYSQWFDGEAEEFDEAEQELEHAYGKSYSIVLNDTEQATDRMASATVAECEKLEREIQKRNVEIQQLHVQEVCSPITDRISFADKSYKPPLKKLEDEYVQLMSDKNKFISFLDQQGQKIEKIRLRISKVKEAVISQEAELEARQSELAHIEQAVAAQNLSPDEVQRMNHERDSLTRSLEDLRNKISEASQFAYDQEMVVTKSMDRFEGLLTDYNSLAHQIGLLDFSLDVPSLAANVNYNLDVDLGAEELEEVKAVGVRMRSTIWQALQTCREMFRQEALGLGNGTIALEDEFDKLGQSVERQKEEVGNLEVRLKIVHNQAEDAQSQIASENSDTNKIITQLETEVTNMLAASQQGVLSTQSQLESTRIAFKELRHKTALFQDSVVAEVGEHIDAIIKAKEHTANSLKSIRALAETQ

NDC80

Probable kinetochore protein NDC80

703 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

78.423 kDa

MDFRRQTLVSNGGSSQPQPSVPSSAIKKASRLGPARQSLAPSQIQSRTSILGVSNSQENASHGMMGSRKSTVPGKMGDRDQLMSASRGDGGIYGRTPQMNRGIPGSVRRSSVFTSNSQGRTSMAPGVYSTAYKDPRPLRDKVFQSNCMRNVNEYLISVRYPLPLTAKTLTSPTAKEFQSIFKFLVNDLVDPGAAWGKKFEDDTLSILKDLKYPGMDSVSKTALTAPGAPQSWPNMLAMLNWLVDLCKALDNWDDPEIISDPLMVPATELPLDYPNLDDRLLWDFAAKTYSQWFDGEAEEFDEAEQELEHAYGKSYSIVLNDTEQATDRMASATVAECEKLEREIQKRNVEIQQLHVQEVCSPITDRISFADKSYKPPLKKLEDEYVQLMSDKNKFISFLDQQGQKIEKIRLRISKVKEAVISQEAELEARQSELAHIEQAVAAQNLSPDEVQRMNHERDSLTRSLEDLRNKISEASQFAYDQEMVVTKSMDRFEGLLTDYNSLAHQIGLLDSSLDVPSLAANVNYNLDVDLGAEELEEVKAVGVRMRSTIWQALQTCRETFRQEALGLGNGTIALEDEFDKLGQSVERQKEEVGNLEVRLKIVHNQAEDAQSQIASENSDTNKIITQLETEVTNMLAASQQGVLSTQSQLESTRIAFKELRHKTALFQDSVVAEVGEHIDAIIKAKEHTANSLKSIRALAETQ

NDC80

Kinetochore protein NDC80

691 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

80.487 kDa

MQSSTSTDQHVLHHMDPHRFTSQIPTATSSQLRRRNSTNQGLTDMINKSIARNTISGTGIPTGGINKNKRTRSTVAGGTNGTALALNDKSNSRNSVSRLSINQLGSLQQHLSNRDPRPLRDKNFQSAIQEEIYDYLKKNKFDIETNHPISIKFLKQPTQKGFIIIFKWLYLRLDPGYGFTKSIENEIYQILKNLRYPFLESINKSQISAVGGSNWHKFLGMLHWMVRTNIKLDMCLNKVDRSLINQNTQEITILSQPLKTLDEQDQRQERYELMVEKLLIDYFTESYKSFLKLEDNYEPSMQELKLGFEKFVHIINTDIANLQTQNDNLYEKYQEVMKISQKIKTTREKWKALKSDSNKYENYVNAMKQKSQEWPGKLEKMKSECELKEEEIKALQSNISELHKILRKKGISTEQFELQNQEREKLTRELDKINIQSDKLTSSIKSRKLEAEGIFKSLLDTLRQYDSSIQNLTRSRSQLGHNVNDSSLKINISENLLDRDFHEGISYEQLFPKGSGINESIKKSILKLNDEIQERIKTIEKDNITLEKDIKNLKHDINEKTQINEKLELELSEANSKFELSKQENERLLVAQRIEIEKMEKKINDSNLLMKTKISDAEELVTSTELKLEELKVDLNRKRYKLHQQVIHVIDITSKFKINIQSSLENSENELGNVIEELRNLEFETEHNVTN

NDC80

Probable kinetochore protein NDC80

673 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

78.517 kDa

MDELRDIRTTGPEDVLNSVDPYRYTSQIPNGKSNNGLNAKMNGNNTLTNMINRSIAKNMGQNASSGSMRRSMRQSLRNSLPRSSIGPQQQQQMNSTQNSTYHNTARDPRPLRDKNFQNLLQQEIFSYLTDQKFDVETNHPISLKSLKQPTQKDFIYMFKWLYLRLDPGYVFTKSLEHEVYSILRTIHYPYLATINKSQISAVGGSNWPKFVGMLHWLVIINKKLDECLEHLDVSINNQVTQDITVLNQPLKTAEEQEKKQEKYELMVERLFIDYITESYKSFLRLEDDYEPYLHDLELSFQRFVHIIETDIAQLTSTTEHLSVECESIVAKNYELKNIKEKNTGLEQEYKRLSHGVQITQAKSKEWPDKLKEIEDEIDKKKRDIRQVSLQIDELTSVLKRKNISGEEIEHKNKESDSISKSLDTVSSRLDQFTGLVRQQRLETESVYKNLQDTLKQYKSATEGLVIARKNLGDHIDESSIELVLPSDLMSEEMIGLTVEELIGDKKSFTDPIKKNLNKIAEDIKMRITNIQTENSKLQIKLEDLRNEITTKNEDLDQLEQQLSSIKSEYEEYRQESQSQLLSQNIKIEKLERKIQNARVESQQKISSIEREAEETRLKLEELKLLQNRERLELHNKVIQLIEYVSNFKINTQSSIEELQNATQKELQRLQTEV

NDC80

Probable kinetochore protein NDC80

661 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

75.839 kDa

MAERRGSSGANGVLNSLNPQRFTSQIPSIGGNTNKKGVPGTNAALTDMINKSLARNGRSSLSRPVPEVRKSLRRSLRSSQRPSIVPGGGPSAYGALQSTRDPRPLRDKNYQAVLQQEIFDYLQSRKFDIETGHAISLKSLKQPTQKDFICIFRWLYRRLDPGYSFKRSLETEVYSILKTIQYPFLDTINKSQISAVGGSNWHKFLGMLHWLMNTSQRLDSCLHKLDESKTMQLTQDITILNQPVTTLDEQDEKHEQYELMVERLFIEYISKCYKSFINMEDDFSPFKEELEIGFDRFVHIIETDINNLGRQEEMLQQDCEMFAARCEGLKLARSKHQALKGDLVKFQNYINAMKNKAEDWPRKLNQMVEEINEKKGLIKDIHAEIDKLRQALSQEDIQEIDQMNQQRDTFSKMLDTVSSKLDNLTGSVKSQKLNLESSSKVFLDTLEKFNASINGFVLARNNLQHPINPAELLIPVKANITLTDSTAITPSTILEGCTDILSSIKPNLLKVNKEIDERISALQTENNQLEKELRGLRDTITSKGHMLESMENELSNIKSEYDEYQQVSHSKLLSQRIEIEKLERKIQNDRHKTQQRVAQAEQEIEDAAFKLKELTLKIQQERVVLHRKLIKVIEYVVSFKMDVQGSIEALHDFSVEQLESL

NDC80

Probable kinetochore protein NDC80

650 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

76.023 kDa

MNVDYPMNNIPQASSLLRKNNGKRLSMASAARTSLLGNLNLNGTSGGASGRNSNIIDSSSLSMGNTGKRRSLLSTPASINRRRQSSLLQAPMSSSQMSSQSQQASQQTQAPFNQDQRPLRDKNYQTLIQQEIYDFLLANKFELEMNHPLTFKTLKQPTQKDFVVIFQFLYNKIDPYYRFTKSIETEVFLLLKILNYPYLDGINRSQISAVGGQNWPNFLGMLYWLVKLNLSVLNLNSKVDLISPDDEFDKIFINYITQSYRAFIDERDDYSEYYDEMKSRFDELNNNIIQDIENISNENNELLNQYNELNGQLDILENSEKKSKALENDLIKFKAYIETMESRKSKWSEILNKITQEIGNCEVELNNIESVKRDYEAQIGQQGLTPNDIDNLNTERDKLSKSIDLISNSLEDLKDVYHNKQINLQKNYQSLENFLKQYNNLIYKIQLKNHNYDYNFEINFRNNTIINETPDLLKPNEIINKNLKDEKIQLLNYKSIINTNVHMHQDEQIKLQEQIDLISELIMERREEIETLEAKLTANKSTYDEIYETMINDTTTYSMQIEKLERELRSIKINTNQGFIEVENKFQNIQIEYDELLYEIHSNRSILHDKIQKIIESTIGFKINIQSNLEDLENLAFDEFEKEDKKLNKN

NDC80

Kinetochore protein NDC80 homolog

642 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).

Belongs to the NDC80/HEC1 family.

73.913 kDa

MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLSINKPTSERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQEREKEPNRLESLRKLKASLQGDVQKYQAYMSNLESHSAILDQKLNGLNEEIARVELECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELKYARGKEAIETQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRAQVYVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITESKRSVRTLKEEVQKLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSENIKEIRDKYEKKATLIKSSEE

NDC80

Kinetochore protein NDC80 homolog

642 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.

Belongs to the NDC80/HEC1 family.

73.868 kDa

MKRSSVSTGGAGRLSMQELRSQDVNKQGLYTPQTKERPTFGKLSINKPTSERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSPLFDDGQPWGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQEREKEPNRLESLRKLKASLQGDVQKYQAYMSNLESHSAILDQKLNGLNEEIARVELECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQKLWNEELKYARGKEAIETQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRAQVYVPLKELLNETEEEINKARNKKMGLEDTLEQLNAMITESKRSVRTLKEEVQKLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKADREYEECMSEDLSENIKEIRDKYEKKAALIKSSGE

Ndc80

Kinetochore protein NDC80 homolog

642 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules.

Belongs to the NDC80/HEC1 family.

73.962 kDa

MKRSSVSTCGAGRLSMQELRTLDLNKPGLYTPQTKERSTFGKLSTHKPTSERKVSIFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLYEFLTENGYVYSVSMKSLQAPSTKEFLKIFAFLYGFLCPSYELPGTKCEEEVPRIFKALGYPFTLSKSSMYTVGAPHTWPHIVAALVWLIDCIKIDTAMKESSPLFDDGQLWGEETEDGIKHNKLFLEYTKKCYEKFMTGADSFEEEDAELQAKLKDLYKVDASKLESLEAENKALNEQIARLEEEREREPNRLMSLKKLKASLQADVQNYKAYMSNLESHLAVLKQKSNSLDEEIGRVEQECETVKQENTRLQSIVDNQKYSVADIERINHEKNELQQTINKLTKDLEAEQQQMWNEELKYARGKEAIEAQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCLVKYRTQVYAPLKELLNESEEEINKALNKKRHLEDTLEQLNTMKTESKNTVRMLKEEIQKLDDLHQQAVKEAEEKDKKSASELESLEKHKHLLESGVNDGLSEAMDELDAVQREYQLTVKTTTEERRKVENNLQRLLEMVATHVGSLEKHLEEENAKADREYEEFMSEDLLENIREMAEKYKRNAAQLKAPDK

NDC80

Kinetochore protein NDC80 homolog

640 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12829748). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores to spindle microtubules (By similarity).

Belongs to the NDC80/HEC1 family.

73.741 kDa

MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIEKYLDEQNSKIDRDYEEFMSEDLLSTLTGILDSYKKKAESI

ndc80

Kinetochore protein NDC80 homolog

640 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores to spindle microtubules.

Belongs to the NDC80/HEC1 family.

74.637 kDa

MRRSSVTNRQSLLPLRVQDANRMGLTTPQSKDRQGFGKLSMSKPHSGTSERKTSFFGKRMSNGTARTSQYGAFGGTEKIKDPRPLHDKAFIQQCIRQLCEFLNENGYSQTLTVKSLQGPSTKDFLKIFAFIYTFICPNYENPESKFEEEIPRIFKELGYPFALSKSSMYTVGAPHTWPQIVAALVWLIDCVKLCCVLRSENPVFEEPQMGEQSENGIDFNQLFLDYTVRCYDQFMEGRDTFEEYDADMCIRLKEAYHVDESNLEALQQESRRLLEEIERLEKEKENEPDRLASMRKLKVSLQADIQKYQNYLTEIESHSTLLEQRVSSVSEDLEATELESRAVQQENLRLKNILDNQKYSVADIERIKYEENELQQTIAKLTKDLDEDKQQLWSEELKYAKMKESVETQLSEFHKIGRKVRLIPPTAEYANGYDFQIQCNLDSEQSSLIHYRNKINVPLVEILSQSEGQIAGATNKKMGVEDMVEQLNTLIGEKKNEVKVQKDEAQKLEETYQQKVEEAEEDEKRWISEIESLEKHRQLLESGVNKSLDEALKDLQKEQQELQLVEHQTEEEMRQVENKLVRVVHAVANHVAVIEKHLEEKRLKVEREYEEFMKEDLLLDLRELLDKYKEKARVLDSPPY

ndc80

Kinetochore protein NDC80 homolog

638 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12514103, PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores to spindle microtubules (By similarity).

Belongs to the NDC80/HEC1 family.

74.477 kDa

MRRSSVTNRQSLLPLRVQDANRMGLTTPQNKDRQGFGKLSMSKPHSGTSEKKTSFFGKRASNGTARTSQYGAFGGTEKIKDPRPLHDKAFIQQCIRQLCEFLNENGYSQALTVKSLQGPSTKDFLKIFAFIYTFICPNYENPESKFEEEIPRIFKELGYPFALSKSSMYTVGAPHTWPQIVAALVWLIDCVKLCCVLRSENPVFEDPPMGEQSENGIDFNQLFLDYTVRCYDQFMEGRDTFEEYDTDVCIRLKEAYHVDESNLEALQQESRRLMEEIERLEKEKENEPDRLASMRKLKASLQADIQKYQNYLTEIESHSTLLDQRVSSISEELEATELESRAIQQENLRLKNILDNQKYSVADIERIKYEETELQQTIAKLTKDLDEDKQQLWHEELKYAKMKESVETQLSEFHKIGRKVRLIPPTAEFANGYDFQIQCNLDSEQSSLMHYRNKINVPLVEILSQSEGHIASSTNKKMGVEDMVEQLNTLIGEKKNEVKVQKDEAQKLEEIYQQKVEESEEHEKRWISEIESLEKHRQLLESGVNKSLDEAMKDLQKEQQELQLVEHRTEEEMRQVENKLVRVVHAVANHVAVIEKHLEEKRLKVEREYEEFMKEDLLLDLRELLEKYKEKARVLDSL

ndc80

Kinetochore protein NDC80 homolog

632 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores to spindle microtubules.

Belongs to the NDC80/HEC1 family.

73.217 kDa

MSRRPSSRYSEMPMRVTDSRMSLINATPQNKDNAFGKLNIPKPQSTTSERRTSFFGKGIGAGGQRNSMFGSYGGSEKMKDPRALHDKAFVQQCIKQLYEFLVDRGFPGSITVKALQSPSTKEFLKIYEFIYNFLEPSFQMPTAKVEEEIPRMLKDLGYPFALSKSSMYSIGAPHTWPLALGALIWLMDAVKLFGGQREQDLLFSDFSDELCDLEDRTEYNKLIMEYCSDTYNKFMQGADTFDDEDDDFLYKLKKLYNVDEALLHSQQEKHSMLMEHVERLERESQTDRLVGKRTEKLRLQTDLQKLQNYRCTLEAHKTGLENKSAGLTEELEAVEMQLEGLKQERTRLQHILENQKFTPADIERINRERNELQQTIHGLSQSLEEGEQLVWNEEVNLSKTKEKAELKVAEYNKLGRKLKLIPLSAENACGHDFEIRADYSATTITQYKTQIQNPLKNMMVEVEEEFSRLSNVNLSLEETVEQVKSNIFDKENDIKQLKEQIRKVDQQLENAMQEMALEDDKWAAELDSAETHKKLFEKNVMQGIEEAEEEVKAAQQQYHVVVQETNEKNRMVVKNMTDLFSSTVNHLFAVEKHCDEQLKRFDKLKDIVREDEADINQLTDLVENFIKKANSL

NDC80

Probable kinetochore protein NDC80

631 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

72.294 kDa

MNASAHKKRLSMMPGTSSASRPSMAGLPQRNNPPPQREPATPAVSELMRSSRRSMAFGRNPRQSSFGLVPQTPMAPMHTRDPRPVRDRHYQQQISQQIYEYLVTNHFEQETRHPLNQRTLSNPTQKDFKTMFEWIFRRIDPGYPFHKSIENEVHAVLRAAKYPWLDSITKSQIVAVGGQSWAYFSGMLHWMVELNTTIEKYHNHDYSGDDGPSLVDEIFNRHARESYFAYLQGDDRFARPDAELCLAEENAEFQEILAEQRAQNPLPEGEDDELDEELSRLEAKWGKIEEAKLLGKNLADDIVKLGAFVDARKEHNARYASQMSQATAEEDNVTSEVESLSRQKLKLQQTIQDQGLSPAELDKLHLDMERQQKALNSLDEIIDEGRQVVSNKESTALAVFDALDRVIKEYTSSVLSYNAWVASDNDLPEIPESVYLIDLREPLSEENLGRHPSVILGGVDPRNQIRPEIVRICNMVTSKVKALQEEALRLQEEIETNQEKLVSQKRHIGELEAKSRRLRETRNALEDSASMNENENSQNTERLENQFVQAQSETALAQSQLKGLQVRLQDAEHERNKLSVEVQQARERLSQDILKQAEVMVAFKAMVQTKLQDFEMFVRANVEEEIRGDHN

ndc80

Kinetochore protein ndc80

624 amino acids

Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

71.859 kDa

MQDSSSYARRYSQAPSSSNLRTTTFGFNGLGTSRTSLAPQRTLVNARQSIDPDGLSSRVLTPTMRPSLAPNTRRSSVRVSNASFISQTPNITSIKDPRPLSDRRYQQECATQVVNYLLESGFSQPLGLNNRFMPSTREFAAIFKHLYNKLDPNFRFGARYEEDVTTCLKALNYPFLDSISRSRLVAIGSPHVWPAILGMLHWVVSLIQCTEKAVAMVYTVEQNSLDDHLVDKVLFDYLVRTYHLYLDESPEESEPEKELKATFNQQNQDLYNQTEALKSTNEELINQIKSAEELDSAIQVLEERYRTMQRDEVKFQSAMSGMKSKMESRTNLMKQLQVNIEEKESQLQLLKEKRDSLKYQVENQDISISEFEKMVSEREQLDRNLNMIGSKISELRKEVFDTDLLIQASIDSLEKKVQKFNSLAYRIGIVPIAAIRSANNDFELEINPEGPNYINLDLKNKVRPFINEVRRSITLEFHEEQNKSLKLQEHVDTVNDLIAELQDELRGIESRLTSVLSECNMLRETASEEKNAFDAESDKLERELQQLKLSSHNSMLQLDQRIQSINIEADQIAHACMEYKNNIYKEVAFVLGEIIHFKLHVQDSLEDLKMDYQKELDDLSRSEL

NDC80

Kinetochore protein NDC80 homolog

568 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity to ensure proper cell division.

Belongs to the NDC80/HEC1 family.

63.332 kDa

MRGGAAGKRRTTVGFGGAPPPPPPSIEQQRHLFNSRDSDASFASSRPSSIGLGGRGASDDRSSMIRFINAFLSTHNFPISIRGNPVPSVKDISETLKFLLSALDYPCDSIKWDEDLVFFLKSQKCPFKITKSSLKAPNTPHNWPTVLAVVHWLAELARFHQHLVSNSTSVPEDNSMNFFAIQSFGHFIRGEDDKVNDLDSQFLGKLEAEKTSVAETISGCEKISGELEAKLESLRKGPSKKESLEKVKADLENDVNKFRTIVVEYTDRNPAMEKVVEEKAKELKAKEEERERISVENKELKKSVELQNFSAADVNRMRRELQAVERDVADAEVARDGWDQKAWELNSQIRNQFHQIQTLAIDCNQALRRLKLDIQFAVNERGETPAAVMGVDYKSVVKPALCSLCDGIKGSSAEKVEELVTLQHHKSEMASKIESKRSLLGSIQLQINDLEEKMKLVKKETQELSTKCDLEAKTLVESVKAEALNLEVVEKEAAEFVKASELRLQEAVKESEEEVQACAAQLFALIDSISKQKEYMDSKISEIKTGVADTASAVSEIYKANFKKNLGI

NDC80

Probable kinetochore protein NDC80

543 amino acids

Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.

Belongs to the NDC80/HEC1 family.

63.097 kDa

MTRRFTMTPNSRNPVKTPVSGMKVAPFPRHSIATEEVRRRDMRVVREKGYRQQCVDGILRFLVENGYDGQVSQKILHNPSSKDFQSIFKFLYGFVDDFTFSSRFEDEVVNVMKNLKYPYCGEITKSQLSAITPHTWPVILSMCSWLVDLISHGTSLLQQEEERSVESCFFEYVCDGYMRFMEGDEDDTALEEEFERRVTEIYTGIFKEIDRKKEELRRIEEMISEARKMSEGREELDRKKRELTDDLNMLIASEKQLEGKKRKYLGAISRLSEEIVKVEEEIESLRAQEDGLRAQITKQRINPEDVKEMNAEKIELFKELERMKPEKESLMKVVGEQEREAQERAEEVEKLFFDLKGLRDEISLRIVKDGKGVPRVANEVSGEVFSGMSGVIVRLEEELNSKSDVLVTAEMNKSILEEARGEKESITSELNSRLGYYSDKLVMAGKLYLEKKEISENEQRKSKTEMELLENELLKLNLESNTSLLMSEQKLQKARIVLDRTLNSINYEREEINKMIFGFYNAAMDIHASIQSQVGDLRALLNK