NAT2

Nucleobase-ascorbate transporter 2

524 amino acids

Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.

57.614 kDa

MDLVKPEEISHPPMDQLQGLEYCIDSNPPWGEAIALGFEHYILALGTAVMIPSILVPMMGGDDGDKVRVVQTLLFLQGVNTLLQTLFGTRLPTVIGGSYAFMVPIISIIHDSSLTRIEDPQLRFLSTMRAVQGAIIVASSVQIILGFSQMWAICSRFFSPIGMVPVIALTGFGLFNRGFPVVGNCVEIGLPMLILFVIFSQYLKNFQFRQFPVVERFALIIALIIVWAYAHVLTASGAYKHRPHQTQLNCRTDMSNLISSAPWIKIPYPLQWGAPSFDAGHAFAMMAAVLVSLIESTGAFKAAARLASATPPPPHVLSRGIGWQGIGILLNGLFGTLSGSSVSVENIGLLGSTRVGSRRVIQISAGFMIFFSMLGKFGALFASIPFTIFAAVYCVLFGLVASVGLSFLQFTNMNSLRNLFIVGVSLFLGLSIPEYFRDFSMKALHGPAHTNAGWFNDFLNTIFLSSPMVALMVAVFLDNTLDYKETARDRGLPWWAKFRTFKGDSRNEEFYTLPFNLNRFFPPS

NAT2

Arylamine N-acetyltransferase 2

290 amino acids

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

Belongs to the arylamine N-acetyltransferase family.

33.542 kDa

MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI

NAT2

Arylamine N-acetyltransferase 2

290 amino acids

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens (By similarity).

Belongs to the arylamine N-acetyltransferase family.

33.429 kDa

MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGEAMELGLETIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYVYIPAANKYSTGMIHLLLQVTIDGRNYIADAGFGSSSQMWQPLELISGKDQPQMPSIFRLTEQKGIWYLDQIRREQYIPNTEFLNSDLLPKTTHQKVYSFTLEPRKIEDFESMNTYLQTSPTSAFTTTSFCSLQTPEGVHCLVGFTLTYRIFNYKDNTDLIEFKTLIEEEVEEVLKNIFKISLGRKLVPKPGNGSFTI

NAT2

Arylamine N-acetyltransferase 2

290 amino acids

Participates in the detoxification of a plethora of hydrazine and arylamine drugs.

Belongs to the arylamine N-acetyltransferase family.

33.833 kDa

MDIEAYFERIGYQNSRNKLDLQTLTEILQHQIRAIPFENLNIHCGESMELSLETIFDQIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISDRNYIVDAGFGRSLQMWEPLELVSGKDHPQVPAIFRLTEENETWYLDQIRREQYVPNQAFVNSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGCTLTYRRFSYKDNVDLVEFKSLKEEEIEDVLKTIFGISLEKKLVPKHGDRFFTI

Nat2

Arylamine N-acetyltransferase 2

290 amino acids

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. 2-aminofluorene and p-aminobenzoic acid (PABA) are preferred substrates for NAT-2. Less activity with anisidine and barely detectable with SMZ.

Belongs to the arylamine N-acetyltransferase family.

33.701 kDa

MDIEAYFERIGYQSTRSKLDLKTLTEILQHQIRAIPFENLNIHCGESMELSLEAIFDQIVRKKRGGWCLQVNHLLYWALTKLGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFINSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGSTLTYRRFSYKDNVDLVEFKSLTEEEIEDVLRTIFGVSLERKLVPKHGDRFFTI

NAT2

Arylamine N-acetyltransferase 2

290 amino acids

Belongs to the arylamine N-acetyltransferase family.

33.649 kDa

MDIEAYYQRIGYKNPRNKLDLESLTDIFQHQIRTVPYENLSIHCGESMELDLEAIFDQIVRRNRGGWCLQVNYLLYWALTTTGFETTMLGGFVYGSNNDKYSTGMIHLIVQVTINGRNYIVDAGFGRSYQMWQPVELISGKDQPQVPSIFRLREEGETWYLDQIRRQQHVPDQEFLNSELLEKKIYQKLYCFTLQPRTIEEFESANTYLQESPSSVFLDKSICSLQTPEGVHCLVGLTLTSRTYNYKENTDLVEFKVLTEEEVEGVLKTIFNISLGKKLVSKNGHLSFTI

Nat2

Arylamine N-acetyltransferase 2

290 amino acids

Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Acetylates only arylamines.

Belongs to the arylamine N-acetyltransferase family.

33.756 kDa

MDIEAYFERIGYQSSRNKLDLEELTEILQHQIRAIPFENLNIHCGESMELNLEVIFDQVVRKKRGGWCLQVNHLLYWALTKMGFEATMLGGYVFNTPANKYSSGMIHLLVQVTLSGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFVNSDLLEKNKYRKIYSFTLEPRTIEDFESINTYLQTSPASLFTSKSFCSLQTLEGVHCLVGSTLTYRRFSYKDNIDLVEFKSLTEEEIEDVLKTIFGVSLERKLVPKHGDRFFTI

NAT2

Putative N-terminal acetyltransferase 2

288 amino acids

Maybe involved in N-terminal acetylation of proteins. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.

32.804 kDa

MMVPRISASPVFKRIFLRWGFVTLPIQKTVSHTLRRDFSAPCRSMVKCLLLRPGISVHSAQDRKFYSTEEKSSQFDENKSKSNNGKKNEPHGIKGLMAKYGYSALIVYILLTCVDLPLCFLGVHSLGEEKIKIYLNRGKQLIGMGEPDESKVIQDVRRKQAHREAVQAENADKVEDASRKTFNERWQEMKDSTLLAELLIAYGIHKSLIIVRVPLTAVLTPSFVKLLQRFGIDLMKKQKKVFQTMASGAKIRYKGNNPSDFIKNEGTALDITKRKPRTKGQKWFDGLM