Protein
4-hydroxy-2-oxovalerate aldolase
Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Function
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
Similarity
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Sequence
MSARSIHIVDTTLRDGSHAVSHQFTAEQIAAIAGGLDAAGVEYIEVSHGDGLAGSSYNYGWAALGDEEMLKAASAAIKKGKLTVLLLPGIGTVEDLKMAADCGAKVVRVATHVTEADIGEQHIGMAKKLGMMAVGFLMMCHMAPPEKVVEQAKLFESYGADYINIADSAGAMLPEDVKARVGAVVEAVKVPVGFHAHNNLTMATANALAAVEAGATFLDGACRGLGAGAGNAQTEALVGVLDKLGYRTGVDFYKVMDVAEDIVEPIMHRPQVVRNAPLMLGYAGVYSSFLLHTYRAAEKFNLDPRDILVELGRRRMVGGQEDMIVDVAYQLAQKRGGN