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Med20

Gene
MED20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Drosophila melanogaster
Length
252 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for activated transcription of the MtnA gene.
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
27.862 kDa
Sequence
MGVTILQPYPLPEGKSGAHIIDQLSKRLLALGATHAGQFLVDCETFISTPQPHNGAPGRAVHVLHNSEYPASTFSIIDNGTGKQVAIVADNIFDLLMLKMTNTFTSKKQTKIESRGARFEYGDFVIKLGSVTMMEHFKGILIEIEYKSCVILAYCWEMIREMLQGFLGIAVNKDFPSYFAPQTIMTAMGQQQLHAKHNDIFEPMDTVKQYLEQFTNYRKHVTLMGGMGSGPGSQQVGPNVHMSPAVAGLHRS

Gene
MED20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Aedes aegypti
Length
219 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
24.518 kDa
Sequence
MGVTILQPYPVENKSGAQTIEFLVKRVLALGAVQVGHFLVDCETYTSIPQIGATKTVHILHNSEQPASVFSILDTGTKQIPLVTDGLFDLLMTRISPVYTSKKQTKIESKGPRFEFGDFLIKLGSVTMSQNFKGVLVEVEYRPCLVASSCWELMREFLQGFLGSNVSNTIPAYFAQRININTNHTKANDVYQPIDTINQYLEHFTNYRKQTTPVVAPRV

Gene
MED20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Anopheles gambiae
Length
218 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
24.279 kDa
Sequence
MGVTVLQPYPLEKSGAQTIDFLLKRVVALGAVPAGQFLVDCETYSSNPQLGPPKTVHILHNSEQPASVFSILDTGTKQIPLVTDGLFDLLMTRIAPAYTSKKQTKIESKGQRFEFGDFVIKLGSVTMSQNFKGVLVEVEYRPCLVPGSCWELMREFLQGFLGSNVSNSMPAYFTQRSSINPNHSKANEIYQPIDTINQYLEHFTNYRKQTMAPVGVRP

Gene
Med20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Mus musculus
Length
212 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.192 kDa
Sequence
MGVTCVSQMPVAEGKSLQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHAPGAPTVFGNRHDAVYGPADTMIQYMELFNKIRKQQQVPVAGIR

Gene
Med20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Rattus norvegicus
Length
212 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.18 kDa
Sequence
MGVTCVSQMPVAEGKSVQQTVELLTKKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQAGKLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPTVFGNRHDAVYGPADTMVQYMELFNKVRKQQQVPVAGIR

Gene
med20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Danio rerio
Length
212 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.318 kDa
Sequence
MGVTCVCQVPVAEGKSVQQTVDLLHRKLEQLGAVKQGNFWVDCETYHATGNATGQPSKLLYVMHNSEAPLSCMALFEGGPGLSADANFDVLMIKLKSHFQNAKGHKVESRGTRYRYCDFLVKIGTVAMSSSARGISVEVEYCACVIPGDCWNLMKEFMQSFLGSNTPELPTVFTNKAEGLYVPVDCMDTMSQYLELFSKVRKQQVLPGSGVR

Gene
MED20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Homo sapiens
Length
212 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.222 kDa
Sequence
MGVTCVSQMPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYGPADTMVQYMELFNKIRKQQQVPVAGIR

Gene
MED20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Macaca fascicularis
Length
212 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.204 kDa
Sequence
MGVTCVSQIPVAEGKSVQQTVELLTRKLEMLGAEKQGTFCVDCETYHTAASTLGSQGQTGKLMYVMHNSEYPLSCFALFENGPCLIADTNFDVLMVKLKGFFQSAKASKIETRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYGPCVVASDCWSLLLEFLQSFLGSHTPGAPAVFGNRHDAVYGPADTMVQYMELFNKIRKQQQVPVAGIR

Gene
med20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Xenopus laevis
Length
211 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.273 kDa
Sequence
MGVTCVSQVPLAEGKSVQQTVEILTRKLEQLGAEKQGTFYVDCETYHTAGASMGTPGQAGKLLYVMHNSEYPLSTFALFENGPCLVADLNLDVLMVKLKGFFQNAKANKMETRGTRYQYCDFLVKIGTVTVGQSGRGITVEVDYCPCAVPGDCWNLMMEFMQSFMGSHAPSVPPVFSAKHDPLYTPADTMVQYMELLNKIRKQQVTVAGMR

Gene
MED20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Gallus gallus
Length
211 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
23.289 kDa
Sequence
MGVTCVTQVPVLEGKSVQQTVELLSKKLELLGAEKHGAFGVDCETYHTAAAISSQGQTGKLMYVMHNSEYPLSCFALFENGPCLIADANFDTLMVKLKGFFQNAKANKIESRGTRYQYCDFLVKVGTVTMGPSARGISVEVEYCPCVIANDCWNLLMEFMQSFMGSHTPGIPSVFGTKHDSIYSPADTMVQYMELFNKIRKQQQVPVAGIR

Gene
med20
Protein
Putative mediator of RNA polymerase II transcription subunit 20
Organism
Dictyostelium discoideum
Length
195 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
22.316 kDa
Sequence
MGYKCIFSFKGQLPEMTKRIEFLGGIKVSTGTINCSLYLERVPDGSNLIPREFHLLLYDEKPKKCFTVCRDTIVETDREMVSILEKTNSYKKRQTTEALISKYELGDFIIRVGPIVFRTEIRGILVEVEYTACSTPVTSPFNCTKLLSEFINGNLGPFPEPIQTSFDFSAYPTLPKSYSDLHTSYQYVNLFRTIN

Gene
med20
Protein
Mediator of RNA polymerase II transcription subunit 20
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
193 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 20 family.
Mass
22.35 kDa
Sequence
MPVHGVIYYSSPSMATFLSPAQDNLVRTYFAQHLKKWVVQYKLYRNAVTPKTLEFLKQNINPSMLACVDEATMIDAEPELEDIIVRTKLWNFRQSFTIEGSIYEVGSFKVAIANVLQKSVWKGILFHVTYDGTESVDLARPIIQEFFLKCFLQNNKSVTPVYESFFNQPRHSLDSKLLLQLFKQRIDTVSQRT