MUS1

DNA mismatch repair protein MSH2

942 amino acids

Involved in postreplication mismatch repair. Binds specifically to DNA containing mismatched nucleotides thus providing a target for the excision repair processes characteristic of postreplication mismatch repair (By similarity).

Belongs to the DNA mismatch repair MutS family.

105.071 kDa

MEGDDFTPEGGKLPEFKLDARQAQGFISFFKKLPQDPRAVRLFDRRDYYTAHGENATFIARTYYHTMSALRQLGSSSDGILSASVSKAMFETIARNILLERTDCTLELYEGSGSNWRLTKSGTPGNIGSFEDILFANNDMEDSPVIVALFPACRESQLYVGLSFLDMTNRKLGLAEFPEDSRFTNVESALVALGCKECLLPADCEKSIDLNPLQDVISNCNVLLTEKKKADFKSRDLAQDLGRIIRGSVEPVRDLLSQFDYALGPLGALLSYAELLADDTNYGNYTIEKYNLNCYMRLDSAAVRALNIAEGKTDVNKNFSLFGLMNRTCTVGMGKRLLNRWLKQPLLDVNEINNRLDMVQAFVEDPELRQGLRQQLKRISDIDRLTHSLRKKSANLQPVVKLYQSCSRIPYIKGILQQYNGQFSTLIRSKFLEPLEEWMAKNRFGRFSSLVETAIDLAQLENGEYRISPLYSSDLGVLKDELSVVENHINNLHVDTASDLDLSVDKQLKLEKGSLGHVFRMSKKEEQKVRKKLTGSYLIIETRKDGVKFTNSKLKNLSDQYQALFGEYTSCQKKVVGDVVRVSGTFSEVFENFAAVLSELDVLQSFADLATSCPVPYVRPDITASDEGDIVLLGSRHPCLEAQDGVNFIPNDCTLVRGKSWFQIITGPNMGGKSTFIRQVGVNVLMAQVGSFVPCDQASISVRDCIFARVGAGDCQLHGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLMEVTRAPTLFATHFHELTALAHRNDDEHQHISDIGVANYHVGAHIDPLSRKLTMLYKVEPGACDQSFGIHVAEFANFPEAVVALAKSKAAELEDFSTTPTFSDDLKDEVGSKRKRVFSPDDITRGAARARLFLEEFAALPMDEMDGSKILEMATKMKADLQKDAADNPWLQQFF