Involved in postreplication mismatch repair. Binds specifically to DNA containing mismatched nucleotides thus providing a target for the excision repair processes characteristic of postreplication mismatch repair (By similarity).

Belongs to the DNA mismatch repair MutS family.

942 amino acids

MEGDDFTPEGGKLPEFKLDARQAQGFISFFKKLPQDPRAVRLFDRRDYYTAHGENATFIARTYYHTMSALRQLGSSSDGILSASVSKAMFETIARNILLERTDCTLELYEGSGSNWRLTKSGTPGNIGSFEDILFANNDMEDSPVIVALFPACRESQLYVGLSFLDMTNRKLGLAEFPEDSRFTNVESALVALGCKECLLPADCEKSIDLNPLQDVISNCNVLLTEKKKADFKSRDLAQDLGRIIRGSVEPVRDLLSQFDYALGPLGALLSYAELLADDTNYGNYTIEKYNLNCYMRLDSAAVRALNIAEGKTDVNKNFSLFGLMNRTCTVGMGKRLLNRWLKQPLLDVNEINNRLDMVQAFVEDPELRQGLRQQLKRISDIDRLTHSLRKKSANLQPVVKLYQSCSRIPYIKGILQQYNGQFSTLIRSKFLEPLEEWMAKNRFGRFSSLVETAIDLAQLENGEYRISPLYSSDLGVLKDELSVVENHINNLHVDTASDLDLSVDKQLKLEKGSLGHVFRMSKKEEQKVRKKLTGSYLIIETRKDGVKFTNSKLKNLSDQYQALFGEYTSCQKKVVGDVVRVSGTFSEVFENFAAVLSELDVLQSFADLATSCPVPYVRPDITASDEGDIVLLGSRHPCLEAQDGVNFIPNDCTLVRGKSWFQIITGPNMGGKSTFIRQVGVNVLMAQVGSFVPCDQASISVRDCIFARVGAGDCQLHGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLMEVTRAPTLFATHFHELTALAHRNDDEHQHISDIGVANYHVGAHIDPLSRKLTMLYKVEPGACDQSFGIHVAEFANFPEAVVALAKSKAAELEDFSTTPTFSDDLKDEVGSKRKRVFSPDDITRGAARARLFLEEFAALPMDEMDGSKILEMATKMKADLQKDAADNPWLQQFF

105.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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