Protein
Putative mRNA-decapping protein
Organism
Acanthamoeba polyphaga mimivirus
Function
Might function as a decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. In addition to the mRNA cap, probably also efficiently hydrolyzes diphosphoinositol polyphosphates (By similarity).
Similarity
Belongs to the Nudix hydrolase family. DIPP subfamily.
Sequence
MEYETNFRKKHICSNCGRSGHEFRNCIEPITSYGIINVCISDEYNESMIIKDKFCTKKNTYYRVSSRKHPEISCFISNHIRVRDHENMYKLDNEMIPYRSNEDIHKFCYYKNRILFMMVSRRFSLGFIEFIRGKYDVSDTKSIINLFQHMYEHEIKFINKNRYKYDNILYHFLNRNNEPKKIVLNRIYEGKYSNEYCEAKIKFNMLLNSSNEENNNIPVYLEFYIKHIKPKWKSPEWGFPKGRRDKRSEENMVCACREFEEETGYKKSDYSVLNKIEPIEEKLTGTNGVNYKHIYYLAINNCDINSDLTDYDTYEIGEIKWFTYDEAMARIRPYHIEKKRILTRVYLFILNYLIHNINNT