MCD1

Sister chromatid cohesion protein 1

566 amino acids

Cleavable component of the cohesin complex involved in chromosome cohesion during cell cycle. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by ESP1 and dissociates from chromatin, allowing sister chromatids to segregate.

Belongs to the rad21 family.

63.29 kDa

MVTENPQRLTVLRLATNKGPLAQIWLASNMSNIPRGSVIQTHIAESAKEIAKASGCDDESGDNEYITLRTSGELLQGIVRVYSKQATFLLTDIKDTLTKISMLFKTSQKMTSTVNRLNTVTRVHQLMLEDAVTEREVLVTPGLEFLDDTTIPVGLMAQENSMERKVQGAAPWDTSLEVGRRFSPDEDFEHNNLSSMNLDFDIEEGPITSKSWEEGTRQSSRNFDTHENYIQDDDFPLDDAGTIGWDLGITEKNDQNNDDDDNSVEQGRRLGESIMSEEPTDFGFDLDIEKEAPAGNIDTITDAMTESQPKQTGTRRNSKLLNTKSIQIDEETENSESIASSNTYKEERSNNLLTPQPTNFTTKRLWSEITESMSYLPDPILKNFLSYESLKKRKIHNGREGSIEEPELNVSLNLTDDVISNAGTNDNSFNELTDNMSDFVPIDAGLNEAPFPEENIIDAKTRNEQTTIQTEKVRPTPGEVASKAIVQMAKILRKELSEEKEVIFTDVLKSQANTEPENITKREASRGFFDILSLATEGCIGLSQTEAFGNIKIDAKPALFERFINA

MCD1

Protein MULTIPLE CHLOROPLAST DIVISION SITE 1

349 amino acids

Required for chloroplast division. Regulates FtsZ ring positioning in chloroplasts. Determines the site of chloroplast division in concert with MIND1. Not directly involved in ring formation, but probably required for MIND1 localization to regulate FtsZ ring formation.

39.416 kDa

MASIDSLQFHSLCNLQSSIGRAKLQNPSSLVIFRRRPVNLNWVQFETKGSFVCKAIGDSSTPDEDIQNTQSDDNVVVVTATTQSDIPHDSEYSISRFRSMVTTLPPVVFLMKKCSVNSIWIGVCITATVLVAAIRAYVVRKSRDNQRAGSVADLVRRGQLRSGDRRGISKSLNYEDPFNNPFVKLDKGSSTVEMCGKVYRLAPVTLTEKEQTIHQKRRSRAYQWKRPTIFLKEGDSIPPDVDPDTVRWIPANHPFATTVSDIDQDLAQNNVYQKQGVPFRIRAEHEAMQKKLEALQNEEKLNNLSIDSQNARDFQRPYKFSAKLEGENIQKNSQENHTGNSSSEETHKS