Protein
Melanocortin receptor 5
Function
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins (By similarity).
Similarity
Belongs to the G-protein coupled receptor 1 family.
Sequence
MNSSFHLHFLDLGLNTTDGNLSGLSVQNASSLCEDMGIAVEVFLALGLISLLENILVIGAIVRNRNLHTPMYFFVGSLAVADMLVSLSNSWETITIYLLTNKHLVMADASVRHLDNVFDSMICISVVASMCSLLAIAVDRYVTIFCALRYQRIMTGRRSGAIIGGIWAFCASCGTVFIVYYESTYVVICLIAMFLTMLLLMASLYTHMFLLARTHIRRIATLPGHSSVRQRTGVKGAITLAMLLGVFIVCWAPFFLHLILMISCPHNLYCSCFMSHFNMYLILIMCNSVIDPLIYAFRSQEMRKTFKEIVCFQSFRTPCRFPSRY