Man2b2

Epididymis-specific alpha-mannosidase

1018 amino acids

Plays an important role in the early step of spermatogenesis.

Belongs to the glycosyl hydrolase 38 family.

115.61 kDa

MGPLRWLPLLGQLLLLWPRAAQPAGPIRAFVVPHSHMDVGWVFTVQESMRAYAANVYTTVVAELVRGGQRRFIAVEQEFFRLWWDGVASEQQKQQVRQLLHEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLISRIDYDLKDAMQEAQMLQFVWHGSPSLSGQQEIFTHVMDHYSYCTPSHIPFSNRSGFYWNGVAVFPEPPPDGVYPNMSEPVTGANIHLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFDNMDPLLDYINQRTAQFGISVQYATLNDYFQALHATNMTWGIRDHQDFLPYSSEPLQAWTGFYTSRSTLKGLARQASALLYAGESMFTRYMWPDPSGTLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVKNMYTEHLRMGMLGVRKLMVSIALGGPPGSGTGAPKDIMGPQVTPVLSVDTRPVGYSASVYNPLAWKITTIITLTVAFPNVSVTDELGHPVSTQIQNSTKDPSAYDLLILTTIPGLNYRHYQVMHARGDQAGTRELVAPRANTLKFSLKLRNQPSQEGKRLVPVMNDCYILLFDQDTNMLHSIQDRQSNRTVRMTQEFLEYQANWDVKQGPISDNYLFAPNNTAEPSWEAVGMEMVAGTLVTDIRQYFYRYITDQEYIYSIHTRLAHPSLAGELLCQRIEQQYRVGPLDLNREAILRTSSDLNSQQVLYSDNNGYQMQRRPYKAFKSNPIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNNLAWDLKYNLTLNDTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHGPHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYEAGEDPVLSRPATVDLKVVLRGLGSVVAVEERSLTGTWDVQMLQRWHWSTKTDHLKGHPTSPPRPPGGSIITVYPKEIRTFFIKFQQ

MAN2B2

Epididymis-specific alpha-mannosidase

1009 amino acids

Belongs to the glycosyl hydrolase 38 family.

113.979 kDa

MGQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFANMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTGFYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVRDMYATHLASGMLGMRKLMASIVLDELQPQAPMAASSDAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHYNIRPTAGAQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWDLSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ

MAN2B2

Epididymis-specific alpha-mannosidase

1009 amino acids

Belongs to the glycosyl hydrolase 38 family.

113.832 kDa

MGRLYWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMQAYAANVYTSVVEELARGQQRRFIAVEQEFFRLWWGGVASDQQKHQVHQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLSSRIDYDLKAAMQEARGLQFVWRGSPSLSEQEEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAIFPKPPPDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFANMNPLLDHINSHAAKLGVSVQYATLGDYFRALHTLNITWRVRDHHDFLPYSTEPFQAWTGFYTSRSALKGLARRASALLYAGESMFTHYMWPAPCGHLDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVRDMYVMHLASGMLGVRKLMASIILDKLQPQAPMAASSGAGPAGHFASVYNPLAWTVTTIVTLTVGFPGVHVTDEAGHPVPSQIQNSTETPSVYDLLILTTIPGLSYRHYSIRPTAGAQEGTQEPAATVATTLQFGRRLRRRTSHVGRHLVPVANDCYTVLLDQDTNLMHSIWERQSNQTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLVTEIRQYFYRNMTARNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSIVHPVLWLLLGSWSLTTALRQRSAMALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHAQNLRKGNRGEVQADLHRVLLRLHHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWDVSMLHRWSWRTGSGRRRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ

MAN2B2

Epididymis-specific alpha-mannosidase

995 amino acids

Can digest both p-nitro-phenyl-alpha-D-mannoside and high mannose oligosaccharide (Man(8)-GlcNAc(2)). May be involved in sperm maturation. Has a possible role in specific sperm-egg interaction since sperm surface mannosidase acts like a receptor for mannose-containing oligosaccharides located on the zona pellucida.

Belongs to the glycosyl hydrolase 38 family.

114.23 kDa

MGPHSWLPLFMQLALLGPQWALHFYKVKVFVVPHSHMDVGWLHTVQESMQVYVPDVYNSVVEALTRGKRRRFIAVEQEYFRLWWDGFASAKRKQQVRQLLAEQRLEFVLGGQVMHDEAVTHFDDQILQLTEGHGFLYETFGIRPQFSWQVDPFGASATTPTLLALAGFNGHIISRIDYDLKDTMQHTQGLQFVWRGSRSLEARQEIFTHVLDQYSYCSDGFMWNGSPRFPDRPFDMDYSAVEMPVSQDSMNHYVLNLVDNVNKRAAWFRTQHVLWPWGCDRQFFNASQQFANMDRLMDHINKHTPELGISMQYATLAEYFQAVFAQDVSWQVRDHRDFLPYSSAPEQTWTGFYTSQSGLKRLARRASALLYAGESLFTRYMLSAAHRFLDPAWALTQLQQLRWAVSEVQHHDGITGTHILAVRDMFVEHLTTGMAGVRKLMDSIAQDMPLTHSGPEPGGHVAMVYNPLAWTVTTVITLTVSFPEVSVTDESGRPVLAQVQDSKETPSAYDLHVLTTIPGLSYQHYIIKPIRKAREDSQEAAATVPSTIQFGLKLRRQDGQVGRNLVPVKNSCYTVFLDKDTNLMHSIWERQSNRTVRMSQEFLAYRSVYGYEEAVTSDNYLFTPNGTAEPAWAAVRMEVVEGQLLSEIRQYFYRQANDSDHTYAIYSRLAHGPQDSAGELLCHRIEQEYRVGPLELNHEVVLRTSTSLNTGLVLYSDNNGYQMQRRTYRHDRNNSVSLNYYPMAQSAFIQDGGSRLVLLSEQAHGVSSQGNGQVEVMLHRRLWNKLEWTLQYNLTHDVTSVVRPVLWLLLGPRTLTTGLRQRSGLELQHRPVVLFRELGGTVQNGPGPRKQEPVTLPPSLHLQILSIPGWKYSSNHTVHLKNLQKGHYRRAKADFRRVLLRLHHLYEAGEHQALSRPVTLNLQSVLRGLGSVVAVEERSLTGTWDVNSLHRWSWKTEDGHHHRGSSRRPLPPLRGPNVTIHPKEIRTFFIHFQEQ