Can digest both p-nitro-phenyl-alpha-D-mannoside and high mannose oligosaccharide (Man(8)-GlcNAc(2)). May be involved in sperm maturation. Has a possible role in specific sperm-egg interaction since sperm surface mannosidase acts like a receptor for mannose-containing oligosaccharides located on the zona pellucida.

Belongs to the glycosyl hydrolase 38 family.

995 amino acids

MGPHSWLPLFMQLALLGPQWALHFYKVKVFVVPHSHMDVGWLHTVQESMQVYVPDVYNSVVEALTRGKRRRFIAVEQEYFRLWWDGFASAKRKQQVRQLLAEQRLEFVLGGQVMHDEAVTHFDDQILQLTEGHGFLYETFGIRPQFSWQVDPFGASATTPTLLALAGFNGHIISRIDYDLKDTMQHTQGLQFVWRGSRSLEARQEIFTHVLDQYSYCSDGFMWNGSPRFPDRPFDMDYSAVEMPVSQDSMNHYVLNLVDNVNKRAAWFRTQHVLWPWGCDRQFFNASQQFANMDRLMDHINKHTPELGISMQYATLAEYFQAVFAQDVSWQVRDHRDFLPYSSAPEQTWTGFYTSQSGLKRLARRASALLYAGESLFTRYMLSAAHRFLDPAWALTQLQQLRWAVSEVQHHDGITGTHILAVRDMFVEHLTTGMAGVRKLMDSIAQDMPLTHSGPEPGGHVAMVYNPLAWTVTTVITLTVSFPEVSVTDESGRPVLAQVQDSKETPSAYDLHVLTTIPGLSYQHYIIKPIRKAREDSQEAAATVPSTIQFGLKLRRQDGQVGRNLVPVKNSCYTVFLDKDTNLMHSIWERQSNRTVRMSQEFLAYRSVYGYEEAVTSDNYLFTPNGTAEPAWAAVRMEVVEGQLLSEIRQYFYRQANDSDHTYAIYSRLAHGPQDSAGELLCHRIEQEYRVGPLELNHEVVLRTSTSLNTGLVLYSDNNGYQMQRRTYRHDRNNSVSLNYYPMAQSAFIQDGGSRLVLLSEQAHGVSSQGNGQVEVMLHRRLWNKLEWTLQYNLTHDVTSVVRPVLWLLLGPRTLTTGLRQRSGLELQHRPVVLFRELGGTVQNGPGPRKQEPVTLPPSLHLQILSIPGWKYSSNHTVHLKNLQKGHYRRAKADFRRVLLRLHHLYEAGEHQALSRPVTLNLQSVLRGLGSVVAVEERSLTGTWDVNSLHRWSWKTEDGHHHRGSSRRPLPPLRGPNVTIHPKEIRTFFIHFQEQ

114.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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