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LSM1

Gene
LSM1
Protein
Sm-like protein LSm1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
172 amino acids
Function
Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step. The LSM1-LSM7 complex binds RNA with a preference for poly-U ends.
Similarity
Belongs to the snRNP Sm proteins family.
Mass
20.307 kDa
Sequence
MSANSKDRNQSNQDAKRQQQNFPKKISEGEADLYLDQYNFTTTAAIVSSVDRKIFVLLRDGRMLFGVLRTFDQYANLILQDCVERIYFSEENKYAEEDRGIFMIRGENVVMLGEVDIDKEDQPLEAMERIPFKEAWLTKQKNDEKRFKEETHKGKKMARHGIVYDFHKSDMY

Gene
lsm1
Protein
U6 snRNA-associated Sm-like protein LSm1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
140 amino acids
Function
Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step. The LSM1-LSM7 complex binds RNA with a preference for poly-U ends.
Similarity
Belongs to the snRNP Sm proteins family.
Mass
16.172 kDa
Sequence
MNQATQIIPFTTSGSLVDYVDRKVIVVLRDGKKLIGILRSFDQFANLMLQYTIERIYVDDMYGDIDRGVYIVRGENVVLLGELDLDKEYDAVKQLRRMPAEELYPLAKLHEEEKKKNIREKGKYLHSVGFSVDGGHDDLY

Gene
LSM1
Protein
U6 snRNA-associated Sm-like protein LSm1
Organism
Bos taurus
Length
133 amino acids
Function
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (By similarity). Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
Similarity
Belongs to the snRNP Sm proteins family.
Mass
15.193 kDa
Sequence
MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTLEEY

Gene
LSM1
Protein
U6 snRNA-associated Sm-like protein LSm1
Organism
Homo sapiens
Length
133 amino acids
Function
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (PubMed:18172165). Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
Similarity
Belongs to the snRNP Sm proteins family.
Mass
15.179 kDa
Sequence
MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTLDEY

Gene
Lsm1
Protein
U6 snRNA-associated Sm-like protein LSm1
Organism
Mus musculus
Length
133 amino acids
Function
Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (By similarity). Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By similarity).
Similarity
Belongs to the snRNP Sm proteins family.
Mass
15.236 kDa
Sequence
MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVQQQTRLEAEKLKVQTLKDRGLSIPRADTLDEY

Gene
lsm1
Protein
Probable U6 snRNA-associated Sm-like protein LSm1
Organism
Dictyostelium discoideum
Length
129 amino acids
Function
Probably involved with other LSm subunits in the general process of degradation of mRNAs.
Similarity
Belongs to the snRNP Sm proteins family.
Mass
14.812 kDa
Sequence
MSSGLGDEVDKKLIVVLRDGRKFIGIMRTFDQFANIVLQDTIERIYVGDCYSDKNLGLFFIRGDNVVILGEIDPDKEVQEKKLKKISWDEITKAAALEKIKKEEEEQLKRRIMTESGLTIDSILNIDDF