GPC

Pre-glycoprotein polyprotein GP complex

507 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

57.515 kDa

MGQVVTFLQSLPEVINEAINIALIAISIICILKGLVNFWKCGVVQLAIFLCLAGRKCDGLMIDRRHELSHVELNLTRMFDNLPQSCSKNNTHHYYKGPKGTTWGIELTLTNTSLDSYANMSRIRSLAFGNITNCDKTGEAGHTLKWLLNELHFNVLHVTRHVGARCRVSEGAGLLIQYNLTIGDHGGEVGRHLIASLAQIIGDNKAAWVGKCDSHCTMDGKCNYTNCEGFTHYNYLIIQNTTWENHCSYSPMSTIRMALNKVAYSSVSRQLLGFFTWDISDSSGAHVPGGYCLEQWAIVWAGIKCFDNAVMAKCNKDHNVEFCDTMRLFDFNQNAIKTLQLNVENSVNLLKRSINGLISDSLVIRNSLKQLAKIPYCNYTKFWYVNDTITGKHSLPQCWLMRNGSYLNETHFKNEWLWESQNLYNEMLLKEYEDRQGKTPIALTDICFWSLVFFTSTVFLQLVGIPTHRHLVGEGCPKPHRITSNSLCACGYYKIPKRPTRWVRKGK

GPC

Pre-glycoprotein polyprotein GP complex

495 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

56.943 kDa

MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTKFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSEVNLTSINLTRSIDVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLGKEYSERQGRTPITLVDICFWSTVFFTSTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH

GPC

Pre-glycoprotein polyprotein GP complex

488 amino acids

Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of GP1 and GP2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

Belongs to the arenaviridae GPC protein family.

56.186 kDa

MGQLFSFFEEVPNIIHEAINIALIAVSLIAALKGMINLWKSGLFQLIFFLTLAGRSCSFRIGRSTELQNITFDMLKVFEDHPTSCMVNHSTYYVHENKNATWCLEVSVTDVTLLMAEHDRQVLNNLSNCVHPAVEHRSRMVGLLEWIFRALKYDFNHDPTPLCQKQTSTVNETRVQINITEGFGSHGFEDTILQRLGVLFGSRIAFSNIQDLGKKRFLLIRNSTWKNQCEMNHVNSMHLMLANAGRSSGSRRPLGIFSWTITDAVGNDMPGGYCLERWMLVTSDLKCFGNTALAKCNLDHDSEFCDMLKLFEFNKKAIETLNDNTKNKVNLLTHSINALISDNLLMKNRLKELLNTPYCNYTKFWYVNHTASGEHSLPRCWLVRNNSYLNESEFRNDWIIESDHLLSEMLNKEYIDRQGKTPLTLVDICFWSTLFFTTTLFLHLVGFPTHRHIRGEPCPLPHRLNSRGGCRCGKYPELKKPITWHKNH

GPC

Pre-glycoprotein polyprotein GP complex

485 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

55.64 kDa

MGQLISFFGEIPTILQEALNIALIAVSIIATIKGVVNVWKSGLIQLLMFVMLAGRSCSVQIGHHLELEHIILNSSSILPFTPTLCKLNKTYFLVRGPFQAHWGVDLAIGSTTVAVENATKTYTLKSKNFTGCFEGNPDPDSAALLVTWLFNSLHHDYKNDPSILCERVSGENSFRFQINISEPEYCEKILSRMANLFGSFENYCLNNRHIKKLIIIRNLTWSQQCHENHMSAMQLITSNIHTQVVRARRILSFFTWSLSDAVGNDMPGGYCLEKWMLIASQLKCFGNTAVAKCNLNHDSEFCDMLRLFDFNRKAIETLQNKTRSQLNIAINAINSLISDNLLMKNRVKELMDIPFCNYTKFWYVNHTKLNHHSLPRCWLVKNGSYLNESEFRNDWLLESDHLISEILSREYEERQGRTPLSLVDVCFWSTLFYTASIFLHLIRIPTHRHIVGEGCPKPHRLRADSTCACGLYKQKRRPLKWVRSN

GPC

Pre-glycoprotein polyprotein GP complex

484 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

55.63 kDa

MGQLVSFFQEIPNIIQEAINIALIAVSLIAILKGLVNLWKSGLFQLLVFLILAGRSCSFKIGRSTELQNITINMLKVFEDHPISCTVNKTLYYIRESENATWCVEIAALDMSVLLSPHDPRVMGNLSNCVHPDIKHRSELLGLLEWILRALKYDFLNYPPLLCEKVTSSVNETRIQINVSDSAGSHDFKETMLQRLAILFGTKLMFDKTPKQFIVIRNQTWVNQCKSNHVNTLHLMMANAGHAVKLRRLQGVFTWTITDAAGNDMPGGYCLERWMLVTSDLKCFGNTALAKCNLNHDSEFCDMLKLFEFNKKAIESLNDNTKNKVNLLTHSINALISDNLLMKNRLKELLDTPYCNYTKFWYVNHTITGEHSLPRCWMVKNNSYLNESEFRNDWILESDHLLSEMLNKEYFDRQGKTPITLVDICFWSTLFFTTTLFLHLVGFPTHRHIQGEPCPLPHKLNSNGGCRCGRYPELKKPTTWHRKH

GPC

Pre-glycoprotein polyprotein GP complex

483 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

54.997 kDa

MGQLVSFIGEIPAIVHEALNVALIAVSIIAIMKGLINIWKSGLFQLIMFLILAGRSCSISIGHHLELQHFIINSTSLLPSMPTLCRINATNSLIRGPFSAQWGLDIFIGDLTILVNPEPGSKTKRMTATNITGCFPNNEDPDSVAQVLSWFFRGVHHDFHLDPTILCDESVTVFRIQMNLTERMYCDRIVSKLARLFGSFGDYCSKVGKKLVIIRNVTWSNQCHEDHVGSMQLILQNAHNQVMRFRKLQNFFSWSLVDSAGNSMPGGYCLEKWMLVASELKCFGNTAVAKCNINHDSEFCDMLRLFDYNKKAIVNLQDKTKAQLDSLIDAVNSLISDNLITKNKIRELMNIPYCNYTKFWYVNHTGLNVHSLPKCWHVRNGSYLNESDFRNEWIIESDHLVSEILAKEYEERQKRTPLSLVDLCFWSTLFYTASIFLHLLHIPTHRHIIGEGCPKPHRLTSDSLCACGFFQLKGRPTRWARIP

GPC

Pre-glycoprotein polyprotein GP complex

483 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

55.598 kDa

MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNVPPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLSKEYSERQGRTPITLVDICFWSTVFFTSTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH

GPC

Pre-glycoprotein polyprotein GP complex

483 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

55.602 kDa

MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLSKEYSERQGRTPITLVDICFWSTVFFTSTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH

GPC

Pre-glycoprotein polyprotein GP complex

482 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

55.607 kDa

MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGKQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGTLQCQVQPKSRLRVCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLSKEYSERQGRTPITLVDICFWSTEFFISTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH

GPC

Pre-glycoprotein polyprotein GP complex

480 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

54.994 kDa

MGQLVSFFQEIPVFFQEALNIALAVVTLLAIVKGVLNLWKSGLFQLLMFLILAGRSCSFRIGYHTSFESFTMTIGGVFHELPALCKVNDTYNLVRLSHNSSLALSVEYGDTGTVMCEHGHVVSGNYTECTGASEEYNWVLDWVLRGLQHDFSRDPVICCEPKKKTNAEFQFRLNLTQRHKGDHYQNKIKTALTHLFGPFAYNEKDPKIFVTMRNTTWTNQCVMSHTDSLRLLASNGGNSFSGRGLKAFFSWSLSDSTGVDMPGGYCLEKWMLIASELKCFGNTALAKCNLKHDSEFCDMIKLFDFNKNAISKLNNNTIEAVNQLTKTVNSLISDNLLMKNRLRELLKVPYCNYTRFWYVNHTRTGEHSLPKCWLVNNGSYLNESDFRNEWILESDHLISEMLSKEYQERQGRTPLTLVDLCFWSAVFYTTTLFLHLVGFPTHRHISGEPCPLPHRLNRHGACNCGRFKRLKKPLVWYKHH

GPC

Pre-glycoprotein polyprotein GP complex

480 amino acids

Glycoprotein G1: interacts with the host receptor.

Belongs to the arenaviridae GPC protein family.

54.455 kDa

MGQLISFFGEIPSIIHEALNIALIAVSIISILKGVINIWGSGLLQFIVFLLLAGRSCSYKIGHHVELQHIILNASYITPYVPMPCMINDTHFLLRGPFEASWAIKLEITDVTTLVVDTDNVANPTNISKCFANNQDERLLGFTMEWFLSGLEHDHHFTPQIICGNVSKGEVNAQVNITMEDHCSQVFLKMRRIFGVFKNPCTSHGKQNVLISVSNWTNQCSGNHLSSMHLIVQNAYKQMIKSRTLKSFFAWSLSDATGTDMPGGYCLEKWMLISSELKCFGNTAIAKCNLDHSSEFCDMLKLFEFNRNAIKTLQNDSKHQLDMIITAVNSLISDNTLMKNRLKELINIPYCNYTKFWYVNHTGFNVHSLPRCWLTKNGSYLNVSDFRNQWLLESDHLISEILSREYEARQGKTPLGLVDVCFWSTLFYVSSIFLHLLRIPTHRHIIGEGCPKPHRLSSNSVCACGLFKQKGRPLRWAGKV

GPC

Pre-glycoprotein polyprotein GP complex

479 amino acids

Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation cleavage of GP1 and GP2, glycoprotein transport to the cell surface plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion.

Belongs to the arenaviridae GPC protein family.

54.825 kDa

MGQLISFFQDIPIFFEEALNVALAVVTLLAIIKGIVNVWKSGILQLFVFLVLAGRSCSFKVGHHTNFESFTVKLGGVFHELPSLCRVNNSYSLIRLSHNSNQALSVEYVDVHPVLCSSSPTILDNYTQCIKGSPEFDWILGWTIKGLGHDFLRDPRICCEPKKTTNAEFTFQLNLTDSPETHHYRSKIEVGIRHLFGNYITNDSYSKMSVVMRNTTWEGQCSNSHVNTLRFLVKNAGYLVGRKPLAFFSWSLSDPKGNDMPGGYCLERWMLVAGDLKCFGNTAVAKCNLNHDSEFCDMLRLFDFNKNAIEKLNNQTKTAVNMLTHSINSLISDNLLMRNKLKEILKVPYCNYTRFWYINHTKSGEHSLPRCWLVSNGSYLNESDFRNEWILESDHLIAEMLSKEYQDRQGKTPLTLVDLCFWSAIFFTTSLFLHLVGFPTHRHIQGDPCPLPHRLDRNGACRCGRFQKLGKQVTWKRKH

GPC

Glycoprotein

427 amino acids

mediates virus attachment to host receptor and fusion of viral and host membrane.

Belongs to the reptarenavirus GPC protein family.

47.176 kDa

MMSHIRLVLCSALLSMMSCPTSGTIGEMLSLAASSNSSICHGMQFTEPTESFMGILPNETLPMFIFSIMHSEAVPKVGKTLRISHDMKLFGGEAVNYMIFVNKILYEPISYYNYTGSCRQQGLSSCVRVYSDLVNGSKGNPSVKLGFTAIELNKTKNTDFHNLGFKICFSCRDHNGIRLVVYNKNNRTAQLMMCPSELIFSQDFTINSTSVNPSEEAAVPLLNVTGYTCIALHNKNMLTHHSPALSSGSKVDNTLEPGCDSNVGLFGHSTGTDYGWGLANFFSAGITNSLQISQLEHVTDAIACKIAKTSNYTTTALFLLNKEEGEIRDHVIEHEVALNYLLAHQGGLCSVVKGPMCCSDIDDFRRNVSDMIDKVHEEMKKFYHEPDPFGGLGTWGFYGTIFGHVLQWIPIIIMVVVVCFVCSWVRK