About Products Protein Database Contact

Fv1

Gene
Fv1
Protein
Friend virus susceptibility protein 1
Organism
Mus musculus
Length
459 amino acids
Function
Retroviral restriction factor that prevents infection by gammaretroviruses. Acts by interacting with the capsid protein ca after entry of the virus into the cell. This interaction presumably disrupt the capsid thereby inactivating the viral genome, making it unable to enter host nucleus and integrate into host genome.
Mass
51.997 kDa
Sequence
MNFPRALAGFSSWLFKPELAEDSPDNDSPDNDTVNPWRELLQKINVADLPDSSFSSGKELNDSVYHTFEHFCKIRDYDAVGELLLAFLDKVTKERDQFRDEISQLRMHINDLKASKCVLGETLLSYRHRIEVGEKQTEALIVRLADVQSQVMCQPARKVSADKVRALIGKEWDPVTWDGDVWEDIDSEGSEEAELPTVLASPSLSEESGYALSKERTQQDKADAPQIQSSTSLVTSEPVTRPKSLSDLTSQKHRHTNHELNSLAHSNRQKAKEHARKWILRVWDNGGRLTILDQIEFLSLGPLSLDSEFNVIARTVEDNGVKSLFDWLAEAWVQRWPTTRELQSPDTLEWYSIEDGIERLRELGMIEWLCVKATCPQWRGPEDVPITRAMRITFVRETRETWKSFVFSLLCIKDITVGSVAAQLHDLIELSLKPTAAGLTSVGSVGVLSLSPWKHQSNS