Retroviral restriction factor that prevents infection by gammaretroviruses. Acts by interacting with the capsid protein ca after entry of the virus into the cell. This interaction presumably disrupt the capsid thereby inactivating the viral genome, making it unable to enter host nucleus and integrate into host genome.

459 amino acids

MNFPRALAGFSSWLFKPELAEDSPDNDSPDNDTVNPWRELLQKINVADLPDSSFSSGKELNDSVYHTFEHFCKIRDYDAVGELLLAFLDKVTKERDQFRDEISQLRMHINDLKASKCVLGETLLSYRHRIEVGEKQTEALIVRLADVQSQVMCQPARKVSADKVRALIGKEWDPVTWDGDVWEDIDSEGSEEAELPTVLASPSLSEESGYALSKERTQQDKADAPQIQSSTSLVTSEPVTRPKSLSDLTSQKHRHTNHELNSLAHSNRQKAKEHARKWILRVWDNGGRLTILDQIEFLSLGPLSLDSEFNVIARTVEDNGVKSLFDWLAEAWVQRWPTTRELQSPDTLEWYSIEDGIERLRELGMIEWLCVKATCPQWRGPEDVPITRAMRITFVRETRETWKSFVFSLLCIKDITVGSVAAQLHDLIELSLKPTAAGLTSVGSVGVLSLSPWKHQSNS

52 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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