FAM120A

Constitutive coactivator of PPAR-gamma-like protein 1

1118 amino acids

May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Belongs to the constitutive coactivator of PPAR-gamma family.

121.888 kDa

MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMSFHPPHYLAARPGPFGMPGMVPPHVPPQMLNIPQTSLQAKPVAPQVPSPGGAPGQGPYPYSLSEPAPLTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSAYFPGSSTSSSSDNDEGSGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGSQMGTVQPIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQADQAAKVEKMRQSVLEGLSFSRQSHTLPFPPPPALPFYPASAYPRHFGPVPPSQGRGRGFAGVCGFGGPYGETVATGPYRAFRVAAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQAAIQGRPPYAASAEEVAKELKSKSGESKSSAMSSDGSLAENGVMAEEKPAPQMNGSTGDARAPSHSESALNNDSKTCNTNPHLNALSTDSACRREAALEAAVLNKEE

FAM120A

Constitutive coactivator of PPAR-gamma-like protein 1

1114 amino acids

Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May participate in mRNA transport in the cytoplasm (By similarity).

Belongs to the constitutive coactivator of PPAR-gamma family.

121.551 kDa

MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPHTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAIGYYSATSKPMAFHPPHYLARPNPFGMPGIVPPYVPPQMLNIPQTSLQAKPVAPQVPSPGAPGQGPHPYNLAEPALTLETSGKNLTEQNYSNIPHEGKHTPLYERSSPINPAPSGSPNHVDSAYFPGSSTSSSSDNDEGSGGAANHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAEGKGNQIGTVQPIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEIKIAVSIEDEASKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPASVPTHLTVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIENLDPRGIQLSALFMSGVDMALFANDACGQPVPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQAEQAAKVEKMRQSILEGLNFSRQSHPLPFPPPAALPFYPTSVYPRHFGPVPPAQGRGRGFAGVCGFGSPYGETVATGAYRAFRVATATGHCGAFSGSDSSRTSKSQGGIQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKNQGAIQGKPPYAASAEEVAKELKSRSGESKSSAMSSDGSLAENGVVAEEKPAPQMNGSAGDTRAPSHSESALNNDSKTCNTNPHLNALSTDSGCRRADALEAAVLKKEE

FAM120A

Constitutive coactivator of PPAR-gamma-like protein 1

1112 amino acids

Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II (By similarity). May participate in mRNA transport in the cytoplasm.

Belongs to the constitutive coactivator of PPAR-gamma family.

121.646 kDa

MGVQGFQDYIEKHCPSAVVPVELQKLARGSLVGGGRQRPPQTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNIELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRLALIRFHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIHDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAVGYYSATSKPMPFHPPHYLARPNPFGMPGMVPPYVPPQMLNIPQTSLQAKPAVPQVPSPGGTPGQAPYPYSLSEPALTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINLAQSGSPNHVDSAYFPGSSTSSSSDNDEGGGGATNHISGNKIGWEKTGSHAEPLARGDPGDQVKVEGSSTASSGSQLAEGKGSHMGTVQPIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKGLMYPYIFHILTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERLAFRKNRLPPEFSPLIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKRLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQALSPKLYEPDQLQELKIDNLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDGKLFQSKLLKASREKTPLIDLCDGQAEQAAKVEKMRQSILEGLSFSRQNHPLPFPPPPALPFYPASVYPRHFGPVPPSQGRGRGFAGVCGFGGHYGETVATGPYRAFRVTAASGHCGAFSGSDSSRTSKSQGGVQPIPSQGGKLEIAGTVVGHWAGSRRGRGGRGPFPLQVVSVGGPARGRPRGVISTPVIRTFGRGGRYYGRGYKSQGAIQGRPPYAASAEEVAKELKSKSGESKSSAVSLAENGVMAEEKPVPQLNGSTGDPRVPSHSESALNNDSKPCNTNPHLNALSTDSACRREAALEAAVLNKEE

fam120a

Constitutive coactivator of PPAR-gamma-like protein 1 homolog

1043 amino acids

May bee involved in the oxidative stress-induced survival signaling. Binds RNA. May participate in mRNA transport in the cytoplasm (By similarity).

Belongs to the constitutive coactivator of PPAR-gamma family.

115.375 kDa

MGVQGFQEYMEKHCPSAVVPVELQKLARGSLVGGGRQRPPQSPLRLLVDAENCLHRLYGGFYTDWVSGGQWNHMLGYLGALAKACYAGNIQLFVFFNGALEKGRLHEWVKRQGNERQTAQQIVSHIQNKGTPPPKVWFLPPICMAHCIRLALLRFHIKVAQSIEDHHQEVITFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGKSLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLAAFHWSLLGPEHPLASLKVRAHQLVLPPCDVVIKAVADYVRNIQDTNDLDAIAKDVFQHSQSRTDDKVSRFKKAIAYYRATNKPLSCPPAHYLGRPNPGGIHSMVPPYPSPQMLNIPQGSVQSRPMTGGKCVSEQNNYSNIPHEGKHTPLYERSSPINPAQSGSPNHVDSNYFPPSSASSSSENEDGNGGSANHVSGNKPTWDKGKKSEKANKKDSTEQAKAEVPSPSGSGNKGTDKKANQPGHMQIPCLLSMPTRNHMDITTPPLPQVAPEVLRVAEHRHKKGLMYPYIFHVLTKGEMKIPVTIEDEINKDLPPAAILYRPVRQYVYGVLFSLAESRKKAERLAFRKNRMPPEFYVPDYPVIIKEWAAYKGKSPQTPELVEALAFREWTCPNLKKLWLGKAVEDKNRRMRAFLACMRSDTPAMLNPANVPTHLMVLCCVLRYMVQWPGIRILRRQELDAFLAQAISPKLYEPDQLQELKIDNLDPRGIQLSALFMSGVDMAFLANDACGQPIPWEHCCPWMYFDGKLLQAKLNKATREKASLIDLCDGQVELATKVEKMRQSILEGLHFSRQNHPLPFPPPPAMPFYPAAMYPRPCGPMPPPQGRGRGFPGVQPMPSQGGKLEIAGTVVGQWAGTRRGRGRGPFPLQVVSVGGANRGRPRGVISTPIIRTFGRGGRYYGRGFKNQGPPQAKPPYATSAEEVAKELKTQSEDSKSSAVSSDGSLAENGLASEEAPASQMNGGSGEARASSNSESALSSDSKLCNTNPHLNALNADSVRHKEQPLEGAVANKEE