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FABP6

Gene
FABP6
Protein
Gastrotropin
Organism
Bos taurus
Length
128 amino acids
Function
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. Stimulates gastric acid and pepsinogen secretion (By similarity).
Similarity
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Mass
14.46 kDa
Sequence
MAFTGKYETESEKNYDEFMKRLGLSSDRIEKGRNFKVISEIQQDGQNFTWSQHYPGGHSISNNFTIGKETEMETVGNKKFKVTVKMEGGKVVVDSANYHHTVEIVDGKLVEVSTFGGVIYERVSKKVA

Gene
FABP6
Protein
Gastrotropin
Organism
Homo sapiens
Length
128 amino acids
Function
Isoform 2: Essential for the survival of colon cancer cells to bile acid-induced apoptosis.
Similarity
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Mass
14.371 kDa
Sequence
MAFTGKFEMESEKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA

Gene
Fabp6
Protein
Gastrotropin
Organism
Mus musculus
Length
128 amino acids
Function
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (PubMed:23251388). Stimulates gastric acid and pepsinogen secretion (By similarity).
Similarity
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Mass
14.486 kDa
Sequence
MAFSGKYEFESEKNYDEFMKRLGLPGDVIERGRNFKIITEVQQDGQDFTWSQSYSGGNIMSNKFTIGKECEMQTMGGKKFKATVKMEGGKVVAEFPNYHQTSEVVGDKLVEISTIGDVTYERVSKRLA

Gene
FABP6
Protein
Gastrotropin
Organism
Sus scrofa
Length
128 amino acids
Function
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). Stimulates gastric acid and pepsinogen secretion.
Similarity
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Mass
14.219 kDa
Sequence
MAFTGKYEIESEKNYDEFMKRLALPSDAIDKARNLKIISEVKQDGQNFTWSQQYPGGHSITNTFTIGKECDIETIGGKKFKATVQMEGGKVVVNSPNYHHTAEIVDGKLVEVSTVGGVTYERVSKKLA

Gene
FABP6
Protein
Gastrotropin
Organism
Oryctolagus cuniculus
Length
128 amino acids
Function
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. Stimulates gastric acid and pepsinogen secretion (By similarity).
Similarity
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Mass
14.404 kDa
Sequence
MAFTGKFEMESEKNYDEFMKLLGLPSDVVEKSRNIKIVTEIKQDGQDFTWSHHYSGGQIMTNKFTIGKESEIQTFGGKKFKAVVNMEGGKVVANFPNYQHTSEIKGDKLVEVSSIGGVTYERVSKRLA

Gene
Fabp6
Protein
Gastrotropin
Organism
Rattus norvegicus
Length
128 amino acids
Function
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). Stimulates gastric acid and pepsinogen secretion (By similarity).
Similarity
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Mass
14.544 kDa
Sequence
MAFTGKYEFESEKNYDEFMKRLGLPDEVIERGRNFKIITEVQQDGENFTWSQSYSGGNIMSNKFTIGKECEMQTMGGKKFKATVKMEGGKVVADFPNYHQTSEVVGDKLVEISTIGDVTYERVSKRVA