Protein
Dual specificity protein phosphatase 1B
Organism
Arabidopsis thaliana
Function
Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Prevents biotic and abiotic stress responses, including ozone, oxidative stress and pathogen attacks; represses MAPK activities during hypersensitive response to limit the spread of the HR response after infection by necrotrophic pathogen such as Botrytis cinerea. May be also involved in ABA and salt responses. Dephosphorylates MPK3 and MPK6.
Similarity
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Sequence
MEKVVDLFGVGEANSQKLLEGGKDLSEIQQGLFIGSVAEANNKDFLKSSNITHVLTVAVALAPPYPDDFVYKVIEVVDRSETDLTVYFDECYSFIDQAIQSGGGVLVHCFMGMSRSVTIVVAYLMKKHGMGFSKAMELVRSRRHQAYPNPGFISQLQQFEKSIQGNA