drap1

Dr1-associated corepressor homolog

550 amino acids

Involved in transcriptional regulation. Component of the NC2 complex which represses RNA polymerase II transcription through binding to tbp and thereby inhibiting the assembly of the preinitiation complex (By similarity).

Belongs to the NC2 alpha/DRAP1 family.

60.893 kDa

MKKKYKTKFPMARIKKIMQKDEEVGKIASATPILISQCLELFMADLVMKTCKITQAKKGKVISVNHLKECIKQESTFDFLTEIVDRIPDDKNEKRGRPKKTEGEDGGEEEEEEEEEMDMGEEEEEEEDEDDDDSDEEEEEAPKKGGKGSRGGKGSRGGRGGARGGASTRKVKSETSPVLKNTTITTTTATTTPTPTPTPNFANSPKDIQSTSLKKPSARKSNTTSPKSSPFLSSSAGSIQSPPLNNNNNNNNNNNNNNNNNGNFNNNNNFNNNNNNFNNNNNFNNNNFNNNNNNNNFNNNSNNNNNNFNNNNFNNNNYNSNEDENNNNNNNNNNKNNNNNNNSNNSNNNNRGQQFLSSSTASTITLPSNQYQPLAPISLPVLNNSNNNNSSNNNNNNNNNNNNNNNNNNEHILGNLNNNNSNRKINTNFDEEDSNHNINKSNINSIMNSSNNSIDNKDNGFNSFTFSNNNSNFNDNNNYNPNNPNNNNDNNGNGIVLPSLSSTNSSSTLPSFSSVPPILNTNNSNSNNSISHILNNLNSKKPNVEDEDFD

DRAP1

Dr1-associated corepressor

205 amino acids

The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).

Belongs to the NC2 alpha/DRAP1 family.

22.324 kDa

MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHMDGDKGPRRGRKSGSSGRKNGGMGSKGKDKKLSGTDSEQEDESEDTDSDGEEETPQVPPQASHPPAHFQSPPTPFMPFTSTLPVPPAPPGASAPDAEEEEDYDS

DRAP1

Dr1-associated corepressor

205 amino acids

The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.

Belongs to the NC2 alpha/DRAP1 family.

22.35 kDa

MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHMDGDKGARRGRKPGSGGRKNGGMGTKSKDKKLSGTDSEQEDESEDTDTDGEEETSQPPPQASHPSAHFQSPPTPFLPFASTLPLPPAPPGPSAPDEEDEEDYDS

Drap1

Dr1-associated corepressor

205 amino acids

The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).

Belongs to the NC2 alpha/DRAP1 family.

22.278 kDa

MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHVDGDKGPRRGRKPGSSGRKNGGTGSKGKDKKLSGTDSEQEDESEDTDTDGEEETPQLPPQASHPPAHFQSPPTPFIPFTSPLPLPPAPPGPSAADAEDEEDYDS

Drap1

Dr1-associated corepressor

205 amino acids

The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).

Belongs to the NC2 alpha/DRAP1 family.

22.326 kDa

MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHTDGDKGPRRGRKPGSSGRKNGGTGSKSKDKKLSGTDSEQEDESEDTDTDGEEETPQAPPQASHPPAHFQSPPTPFMPFTSPLPLPPAPPGPSAPEAEDEEDYDS