Involved in transcriptional regulation. Component of the NC2 complex which represses RNA polymerase II transcription through binding to tbp and thereby inhibiting the assembly of the preinitiation complex (By similarity).

Belongs to the NC2 alpha/DRAP1 family.

550 amino acids

MKKKYKTKFPMARIKKIMQKDEEVGKIASATPILISQCLELFMADLVMKTCKITQAKKGKVISVNHLKECIKQESTFDFLTEIVDRIPDDKNEKRGRPKKTEGEDGGEEEEEEEEEMDMGEEEEEEEDEDDDDSDEEEEEAPKKGGKGSRGGKGSRGGRGGARGGASTRKVKSETSPVLKNTTITTTTATTTPTPTPTPNFANSPKDIQSTSLKKPSARKSNTTSPKSSPFLSSSAGSIQSPPLNNNNNNNNNNNNNNNNNGNFNNNNNFNNNNNNFNNNNNFNNNNFNNNNNNNNFNNNSNNNNNNFNNNNFNNNNYNSNEDENNNNNNNNNNKNNNNNNNSNNSNNNNRGQQFLSSSTASTITLPSNQYQPLAPISLPVLNNSNNNNSSNNNNNNNNNNNNNNNNNNEHILGNLNNNNSNRKINTNFDEEDSNHNINKSNINSIMNSSNNSIDNKDNGFNSFTFSNNNSNFNDNNNYNPNNPNNNNDNNGNGIVLPSLSSTNSSSTLPSFSSVPPILNTNNSNSNNSISHILNNLNSKKPNVEDEDFD

60.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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