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DNAL1

Gene
dnal1
Protein
Dynein light chain 1, axonemal
Organism
Danio rerio
Length
192 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.495 kDa
Sequence
MAKATTIKEALVKWEEKTGEKANDATAVKLYGQIPPIEKMDASLSNLVNCERLSLSTNCIEKIANLNGLKNLKILSLGRNNIKNLNGLEAVGDTLEELWISYNLIEKLKGIHVMKKLKVLYMSNNLVKEWGEFLKLADLPSLVDLVFVGNPLEEKYSADGNWIEEATKRLPKLKKLDGNPVIKQEEETEGES

Gene
dnal1
Protein
Dynein light chain 1, axonemal
Organism
Xenopus laevis
Length
192 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.562 kDa
Sequence
MAKATTIKEALAKWEERTGQKAGEAKEVKLYAQIPPLEKMDASLSTLVNCEKLSLSTNCIEKIANLNGLKYLKILSLGRNNIKNLNGLEAVGETLEELWISYNLIEKLKGIHVMKKLKVLYMSNNLVKDWAEFSKLGELPLLGDIVFVGNPLEEKHTAEGNWMEEAVKRLPKLKKLDGNPVIKQEEEEGDES

Gene
dnal1
Protein
Dynein light chain 1, axonemal
Organism
Xenopus tropicalis
Length
192 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.674 kDa
Sequence
MAKATTIKEALAKWEERTGQKAGEAKEVKLYAQIPPIEKMDASLSTLVNCEKLSLSTNCIEKIANLNGLKFLRILSLGRNNIKNLNGLEAVGETLEELWISYNLIEKLKGIHVMKKLKVLYMSNNLVKDWAEFSKLGELPLLEDMVFVGNPLEERHTAEGNWLEEAVKRLPKLKKLDGNPVIKQEEEEGDES

Gene
DNAL1
Protein
Dynein light chain 1, axonemal
Organism
Bos taurus
Length
190 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.536 kDa
Sequence
MAKATTIKEALARWEEKTSQKPSEAREIKLYAQIPPIEKMDASLSTLSNCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHVMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEEKHSAEGNWVEEATKRVPKLKKLDGTPVIKEDEEEDN

Gene
DNAL1
Protein
Dynein light chain 1, axonemal
Organism
Ciona intestinalis
Length
190 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.406 kDa
Sequence
MSKGTSIKEALSKWEEKNSEKAAEAKEVKLYQMLPPIEKMDASLSTLTVCEKLSLSTNCIEKIANLNGLKNLKILSLGRNNIKNLNGLEAVGDSLEELWISYNSIEKLKGIHVLKKLKVLLMSNNQVKDWGEFNKLQELPVLMELVFVGNPLEEKHSAEGDWQDRVTKSLKALKKLDGTPIIKNDEEEED

Gene
DNAL1
Protein
Dynein light chain 1, axonemal
Organism
Homo sapiens
Length
190 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.533 kDa
Sequence
MAKATTIKEALARWEEKTGQRPSEAKEIKLYAQIPPIEKMDASLSMLANCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEEKHSAENNWIEEATKRVPKLKKLDGTPVIKGDEEEDN

Gene
Dnal1
Protein
Dynein light chain 1, axonemal
Organism
Mus musculus
Length
190 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.465 kDa
Sequence
MAKATTIKEALSRWEEKTGQKPSDAKEIKLYAQIPPIEKMDASLSTLGNCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGETLEELWISYNFIEKLKGIHVMKKLKILYMSNNLVKDWAEFLKLAELPCLEDLVFVGNPLEEKHSAEGNWIDEATKRVPKLKKLDGTPVIKEDEEEES

Gene
Dnal1
Protein
Dynein light chain 1, axonemal
Organism
Rattus norvegicus
Length
190 amino acids
Function
Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (By similarity).
Similarity
Belongs to the dynein light chain LC1-type family.
Mass
21.503 kDa
Sequence
MAKATTIKEALSRWEEKTGQKPSDAREIKLYAQIPPIEKMDASLSTLANCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHVMRKLKILYISNNLVKDWAEFVKLAELPCLEDLVFVGNPLEEKHSAEGNWIEEATKRVPKLKKLDGTPVIKEDEEEES