CYBA

Gene

CYBA

Protein

Cytochrome b-245 light chain

Organism

Homo sapiens

Length

195 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

21.013 kDa

Sequence

MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKYMTAVVKLFGPFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLAAVRGEQWTPIEPKPRERPQIGGTIKQPPSNPPPRPPAEARKKPSEEEAAVAAGGPPGGPQVNPIPVTDEVV

Protein

Cytochrome b-245 light chain: CYBA

Gene

CYBA

Protein

Cytochrome b-245 light chain

Organism

Oryctolagus cuniculus

Length

194 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.708 kDa

Sequence

MGQIEWAMWANEQALASGLILVAGGIVATAGRFTQWYFGTYAIAAGVLVCLLEYPRGSRAKGSTLERCGQRYLTAVLKLLGPLSRNYYFRAALHLALSVPAGFLLATILGTVCLVIASIIYLLAAVRGEQWTPIEPRPKERPQVGGTIKQPPSNPPPRPPVEARKKPGEEDATPAGGPPGGPRVNPIPVTDEVV

Protein

Cytochrome b-245 light chain: CYBA

Gene

Cyba

Protein

Cytochrome b-245 light chain

Organism

Mus musculus

Length

192 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.748 kDa

Sequence

MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIAAGVLICLLEYPRGKRKKGSTMERCGQKYLTSVVKLFGPLTRNYYVRAALHFLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEGEEEAASAGGPQVNPMPVTDEVV

Protein

Cytochrome b-245 light chain: Cyba

Gene

CYBA

Protein

Cytochrome b-245 light chain

Organism

Sus scrofa

Length

192 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.745 kDa

Sequence

MGQIEWAMWANEQALASGLILMTGGIVATAGQFTQWYLGTYSIAAGVLVCLLEYPRGRRTKGSTMERCEQKYMTKVVKAFGPLSRNYYIRAFLHLGLSVPAGFLLATILGTACLAIASGIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPSNPPPRPPPEARKKPGEEAVAGVPRGAPRKTPCPVTDEVV

Protein

Cytochrome b-245 light chain: CYBA

Gene

Cyba

Protein

Cytochrome b-245 light chain

Organism

Rattus norvegicus

Length

192 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.75 kDa

Sequence

MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVLICLLEYPRGKRKKGSTMERCGQKYLTAVVKLFGPLTRNYYVRAVLHLLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEAEEEAASAGGPQVNPIPVTDEVV

Protein

Cytochrome b-245 light chain: Cyba

Gene

CYBA

Protein

Cytochrome b-245 light chain

Organism

Tursiops truncatus

Length

192 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.509 kDa

Sequence

MGQIEWAMWANEQALASGLILITGGIVATAGQFAQWYLGAYSIAAGVLICLLEYPRGKRSKGSTMERCGQKYLTRAVKVFGPLTSNYYIRAFLHLGLSVPAGFLLATILGTACLAIASSIYLLAAIHGEHWTPIETKPKERPQVGGTIKQPPSNPPPRPPAEARKKPSEEEVAGVPGGGPQENPMPVTDEVV

Protein

Cytochrome b-245 light chain: CYBA

Gene

CYBA

Protein

Cytochrome b-245 light chain

Organism

Bison bison

Length

191 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.512 kDa

Sequence

MGQIEWAMWANEQALASGLILITGGIVATAGQFTQWYLGAYSIAAGVLVCLLEYPRGKRSKGSTMERCGQKYLTRVVKLFGPLTRNYYIRAFLHLGLAVPAGFLLATILGTACLAIASGIYLLAAIRGEQWSPIEPKPKERPQIGGTIKQPPSNPPPRPPAEARKKLSEEAAGVPTGGPQENPMPVNDEVV

Protein

Cytochrome b-245 light chain: CYBA

Gene

CYBA

Protein

Cytochrome b-245 light chain

Organism

Bos taurus

Length

191 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Similarity

Belongs to the p22phox family.

Mass

20.496 kDa

Sequence

MGQIEWAMWANEQALASGLILITGGIVATAGQFTQWYLGAYSIAAGVLVCLLEYPRGKRSKGSTMERCGQKYLTRVVKLFGPLTRNYYIRAFLHLGLAVPAGFLLATILGTACLAIASGIYLLAAIRGEQWSPIEPKPKERPQIGGTIKQPPSNPPPRPPAEARKKPSEEAAGVPTGGPQENPMPVNDEVV

Protein

Cytochrome b-245 light chain: CYBA

Gene

cybA

Protein

Superoxide-generating NADPH oxidase light chain subunit

Organism

Dictyostelium discoideum

Length

118 amino acids

Function

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.

Similarity

Belongs to the p22phox family.

Mass

13.008 kDa

Sequence

MGKFKLGNWAAMIGMAACWCLIAGGIMGIWYERRYIAIYSICVGGVLYPLLYPLSFLGPLKAIFHQYYVAAALMAGLSVLCYFLVPTMLAAMVMDISAVVFLISAIKGERGDFFDKQD

Protein

Superoxide-generating NADPH oxidase light chain subunit: cybA