About Products Protein Database Contact

CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Kazachstania servazzii
Length
293 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
34.129 kDa
Sequence
MQSQQYSTPNLSLFNDGSAIIGEIRPIHGANQDVINDRALQLLQRTREHRNFLHRAHDDIRRYEPPTTQIDALENDEDENFYLNDMNTNEEYQSDRESVKSGLNSIANRYKNAVQSSPSDLDDIDFVGEEEQDLSYDESDYSDPLQEIDSNYRESPRRTTDKILKSSSKNYRRRENLGGEIRKIRQEKANKTATRYRPSDLALYEIRKYQQSTDLLISKIPFARLVKEVTDNFILENQHLQWHSMAILALQEASEAYLVGLLEHANLLALHAKRITLMKKDVQLARRIRGQFI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
240 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
28.186 kDa
Sequence
MSTRQAVFERDVDEDRWPRSARGLAGVNTVFEGDSEINSKAMRLLEKTRHRRNLLNRREDRRRYLGGVKAKAIESDYYHRNQLPSSYDAGNDDFEPINNSHVESEEENKRLPEKYSLDKYVKRSRKQRDHRHIVAKPKEKRNFAPSKLAMYEIEKYQRSTALLIQKIPFAKLVKEVTEEFAGESQDLRWQSMAILALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
229 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required for functional chromatin architecture at the yeast 2-micron circle partitioning locus and promotes equal plasmid segregation.
Similarity
Belongs to the histone H3 family.
Mass
26.841 kDa
Sequence
MSSKQQWVSSAIQSDSSGRSLSNVNRLAGDQQSINDRALSLLQRTRATKNLFPRREERRRYESSKSDLDIETDYEDQAGNLEIETENEEEAEMETEVPAPVRTHSYALDRYVRQKRREKQRKQSLKRVEKKYTPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
211 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
24.442 kDa
Sequence
MARLSGQSSGRQTGQGTSAEAIRQQREELRRQRELRLQQQQQAERQQQRQQYRTEQSPIVPAATSSSRYSQFGIYRNQPGDVVDTLASSLPRRTTTTRPEVNRTVPRVKKRYRPGTKALREIRQYQKSTDLLIRKLPFARLVREISLDFVGPSYGLRWQSNAILALQEASESFLIHLLEDTNLCAIHAKRVTIMQKDIQLARRIRGQSWIL
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
204 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
23.919 kDa
Sequence
MEQSMSSEQAERVAGRVEQLGGFQNNESINQRALLLLQRNRQRRQLLQRQEDRTRYIPDDAKRRVVERVAEPAAAESRADGAREEERAARPARPRETRRIAKKPQRYRPSDVALQEIRRYQRSTELLISRMPFARLVKEVTDQFTTVDQQMRWQSMAILALQEASEAYIVGLLEHTNLLALHAKRVTVMRKDMQLARRIRGQFI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Kluyveromyces marxianus
Length
192 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
22.435 kDa
Sequence
MEQSVRSIDGARSVAGAGRTIIDRESINQRALQLLQRNRQRRLLLKRSEDRARYIPERREQKRELDETLETRNVPQHHISAHERITKAKSHGSKYKPSDLALAEIRKYQRSTDLLISRMPFARLVKEVTDQFASDEEPLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMRKDMQLARRIRGQFI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
184 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
21.41 kDa
Sequence
MEQSIRSIDGSRSLSNVGASLIDRESINQRALQLLQRNRRRRLLLNRSEDKARYIQPERSASSQQIHPPEHHISAHERITKARGTRYKPTDLALAEIRKYQRSTDLLISRMPFARLVKEVTDQFTTESEPLRWQSMAIMALQEASEAYLVGLLEHTNLLALHAKRITIMRKDMQLARRIRGQFI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Millerozyma farinosa
Length
158 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
17.938 kDa
Sequence
MARISTSSNRPVPTSSALRRQRERDDGGRSTRAPGHNTGLYGNQPGDPPTIRSTNTTVKRRYRPGTKALREIRRYQRSSELLIRKLPFARLVKEVAENYIGADYGIRWQSNAVLALQEACEAFLVHLLEDTNLCAIHAKRVTIMQKDIQLARRIRGNI
Protein
Histone H3-like centromeric protein CSE4: CSE4

Gene
CSE4
Protein
Histone H3-like centromeric protein CSE4
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
150 amino acids
Function
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).
Similarity
Belongs to the histone H3 family.
Mass
16.55 kDa
Sequence
MARISLASSSAGVAGKPRGGGGLHPLGQTRKTLPGERRDTTQKITKPRYKPGQKALKEIRRYQRGTELLIAKLPFARVVREVALNYLGSEYGNLQWQSMALLALQEAAEAFLVHLFEDVNLCAIHAKRVTIMQKDMQLARRIRGAWGGAG
Protein
Histone H3-like centromeric protein CSE4: CSE4