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CARS

Gene
Cars
Protein
Cysteine--tRNA ligase, cytoplasmic
Organism
Mus musculus
Length
831 amino acids
Similarity
Belongs to the class-I aminoacyl-tRNA synthetase family.
Mass
94.86 kDa
Sequence
MAGSSAEQAADYRSILSISDEAARVQALDQHLSTRSYIQGYSLSQADVDVFRQLSAPPADSRLFHVARWFRHIEALLGGPQGRDEPCRLQASKGRRVQPQWSPPAGTEPCRLRLYNSLTRNKDVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYREQKPPATQLLKDVRDAMKPFSVKLSETTDPDKRQMLERIQNSVKLATEPLEQAVRSSLSGEEVDSKVQVLLEEAKDLLSDWLDSTGGSEVTDNSIFSKLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYASNGSVYFDTAKFAASEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFMNEFFLNVKDILRAPVDITGQFEKWEAEEVELNKNFYGKKTAVHEALCDNIDTRTVMEEMRALVSQCNLYMAARKAERRRPNRALLENIAMYLTHMLKIFGAIEEESPLGFPVGGPGTNLNLESTVMPYLQVLSEFREGVRKIAREKKVLEVLQLSDALRDDILPELGVRFEDHEGLPTVVKLVDRDTLLKEKEGKKRAEEEKRRKKEEAARKKQEQEAAKLAKMKIPPSEMFLSEVNKYSKFDENGLPTHDTEGKELSKGQAKKLKKLFEAQEKLYKEYLQMLQNGSLQ
Protein
Cysteine--tRNA ligase, cytoplasmic: Cars

Gene
CARS
Protein
Cysteine--tRNA ligase, cytoplasmic
Organism
Gallus gallus
Length
748 amino acids
Similarity
Belongs to the class-I aminoacyl-tRNA synthetase family.
Mass
85.801 kDa
Sequence
MAAAPAEQGKGKRVQPPWSPPEGTKHSRLCLYNSLTRNKEIFQPQNGKKVTWYCCGPTVYDASHMGHARSYISFDILRRILRDYFKFDVFYCMNITDIDDKIIKRTRQNYLFEQYRKNKSTPAQLLEDVKTASELFSVKLSETTDPDKRQMLEKIQNAVKSAFDPLQEAVQAKLPAEEISRCHEILLEEAKDLLSDWLDSKFGSQVTDNSIFSELPKFWEGEFHKDMEALNVLPPDVLTRVSEYVPEIVAFVKKIVDNGYGYVSNGSVYFDTVKFGSSEKHSYAKLVPEAVGDQKALQEGEGDLSISADRLCEKHSPNDFALWKSSKPGEPSWDSPWGKGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFENDNWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALQKHTARQLRLAFLMHSWKDTLDYSSNTMESAIQYEKFMNEFFLNVKDILRAPTDVTGQFQKWENQEAELNKNFYDKKAAIHEALCDNVDTRSVLEEMRSLVSQSNSYIAAKKSARQMPNRLLLENISCYLTQMLKIFGAIESDDAIGFPVGGNNQNINIESTVMPYLQVLSEFREGVRQIAREKKVTEVLQLSDALRDDILPELGVRFEDHEGLPTVVKLVDKDTLLKEREEKKKIEEEKKRKKEEAARKKQEQEAAKLAKMKIPPHEMFKSEHDKYSKFDENGFPTHDTEGKELSKGQIKKLKKLYETQEKLYKEYLQMVQNGSAN
Protein
Cysteine--tRNA ligase, cytoplasmic: CARS

Gene
CARS
Protein
Cysteine--tRNA ligase, cytoplasmic
Organism
Homo sapiens
Length
748 amino acids
Similarity
Belongs to the class-I aminoacyl-tRNA synthetase family.
Mass
85.473 kDa
Sequence
MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
Protein
Cysteine--tRNA ligase, cytoplasmic: CARS

Gene
CARS
Protein
Cysteine--tRNA ligase, cytoplasmic
Organism
Macaca fascicularis
Length
748 amino acids
Mass
85.452 kDa
Sequence
MAGSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYLEKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHEVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGSDVTDNSIFSKLPKFWEGEFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSDGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTITGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHEALCDNVDTRTVMEEMRALVSQCNLYMAARKAMRKRPNRALLENIALYLTHMLKIFGAIEEESSLGFPVGGSGTSLNLESTVMPYLQVLSEFREGVRKIAREQKVPEVLQLSDALRDDILPELGVRFEDPEGLPTVVKLVDRNTLLKEREEKRQVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDAEGKELSKGQAKKVKKLFEAQEKLYKEYLQMPQNGSFQ
Protein
Cysteine--tRNA ligase, cytoplasmic: CARS

Gene
cars
Protein
Cysteine--tRNA ligase, cytoplasmic
Organism
Xenopus laevis
Length
747 amino acids
Similarity
Belongs to the class-I aminoacyl-tRNA synthetase family.
Mass
85.784 kDa
Sequence
MTESWEQGKGRRTQPPWSAPNTNEQPGLRLYNSLTRSKELFFPQVGRKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQYRESNPPHSDLLQDVNTALIPFLQRISETNDPDKKQMLERIQTAVSAALLPLQDALNKNTGAEELQKHSQVLMEAAVDLLSDWLDEKHGAQIADNSIFSQLPKYWEGEYHKDMEALNVLTPDVLTRVSEYVPEIVAFVQKIVDNGYGYVSNGSVYFSTAKFHDSENHFYAKLVPEAVGDQKALQEGEGDLSISADRLSEKQSPNDFALWKASKPGEPSWESPWGKGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFDNDHWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALQKNTARQLRLAFLMHSWKDTLDYSNNTMESAVQYEKFMNEFFLNVKDLLRAPTDITGQFVKWEVLEIELNNCFYSKKAAIHEALCDNIDTRTVMEEMRSLVSQCNSYIASKKVAKQFPNRMLLRSISSYLTSMLKVFGAIEGEEVIGFPIGGSENSMNLESTVMPYLQVLSQFREGVRQIARQHKVTEVLQLSDLLRDDILPELGVRLEDHEGLPTVVKLVDRETLLKEKEEKRKAEEEKQRKKEEAARKKQQQEAAKLEKMKISPSQMFTLETDKYSQFDESGFPTHDTEGKELSKGQTKKLRKLFEVQEKLHKEYLQMVQNGTTA
Protein
Cysteine--tRNA ligase, cytoplasmic: cars

Gene
cars
Protein
Cysteine--tRNA ligase, cytoplasmic
Organism
Xenopus tropicalis
Length
747 amino acids
Similarity
Belongs to the class-I aminoacyl-tRNA synthetase family.
Mass
85.477 kDa
Sequence
MTDSWERGKGRRTQPPWSAPNTQAQPGLRLYNSLTRSKELFVPQDGNKVTWYCCGPTVYDASHMGHARSYISFDILRRVLRDYFKYDVFYCMNITDIDDKIIKRARQRHLFQQYRERNPRPSDLLQDVSAALTPFLQRISEANDPDKRQMLERIHGSVSAALLPLQDAVSSNARAEELERLSQELMEAAVDLLSDWLDEKHGAQITDNSIFSQLPKHWESEYHRDMEALNVLPPDVLTRVSEYVPEIVAFVQRIVDNGYGYVSNGSVYFSTAKFHASEKHYYAKLVPEAVGDQKALQEGEGDLSISADRLSEKQSPNDFALWKASKPGEPSWESPWGKGRPGWHIECSAMAGSILGESMDIHGGGFDLRFPHHDNELAQSEAYFDNDHWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALQKNTARQLRLAFLMHAWKDTLDYSSNTMESAVQYEKFMNEFFLNVKDLLRAPTDVTGQFVKWEVPELELNSCFYSKKAAVHEALCDNIDTRTVMEEMRSLVSQCNSYIASRKAAKQPPNRLLLRSVSSYLTAMLKVFGAIEGEEVIGFPIGGSDNSMNLESTVMPYLQVLSQFREGVRQIARQHKVTEVLQLSDLLRDDVLPELGVRLEDHEGLPTVVKLVDRETLLKEKEEKRKAEEEKQRKKEEAARKKQQQEAAKLEKMKVSPSQMFQLETDKYSQFDESGFPTHDTEGKELSKGQSKKLRKLYEAQEKLHKEYLQMAQNGTTG
Protein
Cysteine--tRNA ligase, cytoplasmic: cars

Gene
CARS
Protein
Cysteine--tRNA ligase
Organism
Acanthamoeba polyphaga mimivirus
Length
509 amino acids
Similarity
Belongs to the class-I aminoacyl-tRNA synthetase family.
Mass
59.332 kDa
Sequence
METELSETILPTVTKMYVCGPTVYNDAHIGHARIYVIVDLINRTMNKILNKPTHLVMNVTDIDDKIIRESKNKGITWLELARLHENSFFDCMSKLNVTRPDSVIRVTESISDIVLYIQQIINNGFAYIVSDSSVYFDSIEYKKAGYEFSEIDDEEEQQYESLLSKEIVSQKKHHKDFALWKGRSESDVGFNVEFIFDNQTFKSFGVPGWHIECSAMIKKTLGNSIDIHFGGIDLKFPHHYNECLQANAYHHPMYNPLHQSDTMIFHTWTREFIHVGHLCIKGQKMSKSLKNFSTIKEMLDKINSNQFRWLFMSTKWKQQVDFTDGLISIAKELDFTVVNFVNRVSNYPFEVSDVEFNDKETLLHDDFYRIQQRIYSYLTEFKFEMVARSIQHLIGTTNVYLDLPRPNESIVGKIRDYLLDLLDKLGFIYRVGNSSSSHKIKDLMNILIETRSQLRQLTRNPDLSPGIKKQLFDILDRQRNIQLPDIGIILEDSKDSSLWYENSCVQSSE
Protein
Cysteine--tRNA ligase: CARS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Thermofilum pendens (strain DSM 2475 / Hrk 5)
Length
204 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
22.173 kDa
Sequence
MRISVYACFLGLYFLVFSLIVYVILGAEFLVSVLQPGNVARSMLWVLPAYVANASPVVFSRLVRKRWRLHPMDFGLTFVDGQRLLGDNKTFEGFLGGMLSGVLVGILLAYARFVDGVSAFLLPLGALLGDLGGAFVKRRLRIKPGEPAILLDQLDFVAGALILQGLFSKLPAAEVVVAVVLLTPIVHLLTNMAAFVLGLKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)
Length
189 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.794 kDa
Sequence
MVAETVAIAVWAMLPAYVPNNVAVLAGGGRPIDGGRTLDKLTDEDGVLYDENRILGDGKTWRGTAFGTAAGVVLALLLNQLQPFVAGTVGVPQFPIAAAVALAFGAMLGDILASFLKRRTGRQRGAAFPGVDQLDFVIVSLALTAIVATGWFLATFTLPVLVAIFVLTPVLHVSTNGLAYAFGLKDEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Length
187 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
20.445 kDa
Sequence
MDILTLIFYSIYLMIPAYLANGSALVFGGGTPMDFGHYCWDNRRLIGNGVTWRGTVCGGLFGMVIGGILGLLATYGIGSYFFNITASQITFMSGFVPQGLLVGFLLGFGALIGDAIGSFLKRRLNFERGKPVPLLDQLDFVVVSLLFVSTVVSLSLEMIVIIILVSIFLHLGANMFAYMINLKDVWY
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Length
184 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
20.277 kDa
Sequence
MVNIIMVLYSIFLFLPAFIANPGAVITGGHFILDRGKTIHGKRILGDGKSLSGFIGGSLIGVLAGIIVYYIIYISNIGLGNYGNNIISALPVLFAMSFGSLTGDITGSFIKRRLGMKRGAKGSLLDQWPFVLMSFLFIFIFARHFFLEFYGNFIAIILILVLTPPLHRGVNILGYKLKMKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Length
183 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
20.032 kDa
Sequence
MNYPLLMAQAIILFVPALIANSGAVLTGGYFVLDRGKNFIDGRRILGDGKTLSGYLGGSFIGIVSGVIIYWISYATHFILGNYGSIALSIEIPAVMAFGSLTGDILGSFVKRRIGIKSGGKGGLLDQWPFALVAFLFLFLMERPFFLHYYFFAGIIVILAIVPPLHRAVNIIGYKLHKKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Length
181 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.79 kDa
Sequence
METVDTVVWALWAMLPAYIPNNAAVLAGGGRPIDGGRTWGGRRVLGDGKTWRGTLIGTAAGTALALGLTQVTPSVSAALGTDLPTFSLRAGLGLAFGAMLGDIGASFLKRRTGRERGAAFPGLDQLDFVVGALLCAFVAAPSWFTETFTLPVLVVVVVATPVLHVVTNGIAYLLGLKNEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)
Length
181 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.243 kDa
Sequence
MDLVGTVVVAVWAMLPAYVPNNAAVLAGGGRPIDGGRSLGGRRLLGDGKTWRGTAVGTAAGVALAVALNALRPAAADALGVVLPAFPPAAMGTLAFGAMVGDIAASFLKRRTGRQRGAAFPVVDQLDFVVVALALTALAVPAWVGDTFGLPVLVTVAVLTPALHLLTNGIAYALGVKDEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
181 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.243 kDa
Sequence
MDLVGTVVVAVWAMLPAYVPNNAAVLAGGGRPIDGGRSLGGRRLLGDGKTWRGTAVGTAAGVALAVALNALRPAAADALGVVLPAFPPAAMGTLAFGAMVGDIAASFLKRRTGRQRGAAFPVVDQLDFVVVALALTALAVPAWVGDTFGLPVLVTVAVLTPALHLLTNGIAYALGVKDEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)
Length
181 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.93 kDa
Sequence
MDMIIEVVATAVWTMLPAYVPNNVAVLTGGGAPIDGGRTLGGRRILGDGKTWRGTGFGTLAGVAVALGLNTILPILTRVGADLTPFSLEAAVGLAFGAMLGDIVASFFKRRSGRRRGVPFPVIDQLDFVVGGILCAVILAPRWVIATFTPPVVIAVFILTPILHLGTNAGAYVLGFKKEPY
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)
Length
180 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.602 kDa
Sequence
MIGSLVATAFWAMLPAYVPNNAAVLAGGGRPIDGGRDWRGARLLGDGKTWRGTAVGTLTGVVLALALNRIAEPASAALGVDLPTFALPAAFALAFGAMCGDIGASFLKRRSGRERGAAFPGLDQLDFVVVALAAVFVVDTDWALAVFTPSVLVVVLVMTPILHVVTNVGAYALGLKNEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
179 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids. Can use CTP or dCTP, but not ATP, GTP or TTP.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.884 kDa
Sequence
MLDLILKTIWLLLPCYTPNNFAVLVGGGTPIDFGKTFVDGKRILGDGKTWRGFVGGVAGGVLTANLQYAIEKLSGLAIYSSLPFNEFFTLTFLLAFGAMFGDLCGSFIKRRFGYERGSRFLIVDQLMFLLVALLIASLYPPFWKLFTAEIIALAVIITPALHMGINYIAYRLNLKEVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.831 kDa
Sequence
MDLLLLLFSALWYILPAYVANAVPCILGGGKPVDFGKNFFDGNRIIGNGVTYRGTFFGILFGIITGILQHFIVILYMGPKSVFNYGLTGYIILSFLLATGALFGDMLGSFIKRRFNLNQGQSAPLLDQITFIIFALLFAYSLYPVPANIIVLLLVISPIIHFSSNIIAYKLHLKKVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.118 kDa
Sequence
MNIIVHSIWLMLPAYVPNNFAALFGGGTPLDMGMSLPDGHRVFGNGKTIRGTIAGVAGGIIVGLLQNSIAGVFGLPSFGDGMELFLVLFGLSAGSMLGDLTASFIKRRLGMKRGASFFLVDQLDFVMGAWALTFLLAPEWFNAQFTSPVIILVLLITPVLHRFANVIGYMIGAKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
20.102 kDa
Sequence
MDLINLLFVSFWFILPAYTANAMACIFGGGKPVDLNKNFIDQKRLIGNGVTYRGTFFGVFFGIVTAIIQYLVSNLGFKFILSFNFTLIEYVIIGFLLSFGALFGDMFGSFLKRRLGFKQGQSAPVLDQITFIVFALIFVSYYYLVPSKISITLLILSPVVHILSNIIAYKLGLKKVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.357 kDa
Sequence
MSIIYLVINSFIFILPAYVANATPCIFGGGAPIDGGKCFFDGRRIIGNGVSWKGTFFGLFCGTITAILEGIIFNLNIFGTVAFNFNVFEWGIVGLLLSAGALFGDAIGSFIKRRLGLAQGRPAPILDQLGFIVFALLFVYPFAPVSYEMGIFLLVITPMIHLSANIIAYKLGIKDVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.993 kDa
Sequence
MDLLLLLFSAIWYILPAYIANAVPCILGGGRPVDFGKNFFDGYRLIGNGVTYRGTFFGILFGIITGILQHFIVILYMDPESAFNYGLSGYIILSFLLATGALFGDMLGSFIKRRFKLNQGQSAPLLDQITFIVFALLFAYPFYPLPINTIILLLVISPLIHLSSNIVAYKLHLKKVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.932 kDa
Sequence
MDLLLLLFSAIWYILPAYVANAVPCILGGGKPVDFGKTFFDGNRIIGNGVTYRGTFFGILFGIITGILQHFIVILYMGPETVFDYGLFGYIILSFLLASGTLFGDMLGSFIKRRFKLNQGQSAPILDQITFIVFALLFAYPFYPLATNSIVLLLVISPIIHFSSNIIAYKLHLKKVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Length
178 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.939 kDa
Sequence
MDLLLLLFSAIWYILPAYVANAVPCILGGGRPVDLGKNFFDGNRIIGNGVTYRGTFFGILFGIITGILQHFIVILYMDPQSVFNYGLTGYIILGFLLGTGALFGDMLGSFIKRRLKLNQGQSAPLLDQMTFIVFALIFAYPLYQQPVNLMVILLVISPIIHFSSNIIAYKLHLKKVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
177 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.46 kDa
Sequence
MFYRLLFASLWYILPAYVANASACIFGGGTPVDLGKNFIDGRRLIGNGVTYRGCIFGILCGTLVGLIQGILVDFNIFNSLDFYGTVLDHVILAFFLSVGAIVGDAVGSFIKRRLNIERGKPAPLLDQLDFVIGALAFGYIVAPIPYEMIIIICLFTVFVHLLGNIIAYKLGIKDVWW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Length
176 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.399 kDa
Sequence
MQSIILFIPALIANSGAVITGGHFIIDRGKKFIDGRRILGNGKTLSGYAGGIAIGTVTGFIIYLISTLFNYALGTYGTLAEAIIIPFIMATGSLTGDIAGSFVKRRIGIDRGGKGGLLDQWPFALMAFLFLYIFERPFFMYHYFYVTMIVILVIVPPIHRAVNIIGYKMHKKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)
Length
176 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
20.205 kDa
Sequence
MSGYMISPEYYFIYWFLKYYLSPMIANASPVLVKGIHRIDFSHIFIDGKPLFGKNKTWEGFYVGVLMGFLTSIGIGIILCEEEYILIGLGSSIFALIGDLLGSFIKRRMNIASGEPLPIIDQLDFALMATLYYYFLGIEEFISYPLYILYSLIIILALHIITNNIAYYLGVKDKRW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length
176 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.178 kDa
Sequence
MIPAYIPNPAAALLGGGTPVDFGKCAKDGRRILGDGKTWRGLIGGIVVGIIFGLMQIFLYNYFNLEFLPKQTIITVCALATGALLGDMVKSYFKRRLGKDRGAKWPIADMYDMVVGSLVLMTLALLVTGNLNWFTENFDSVGFLIATIIAILILSPLLHRGTNIIGYLLGLKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
175 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.18 kDa
Sequence
MIPAYLSNPFAAVFGGGKPIDGGRTYKDGRRILGDGKTYRGLFSGIFCGFLAGCVEVWLSFRGFEILGIEMPGFGPDYTSSLIVVLALASGALFGDMFKSFFKRRMGLKRGASLPLVDQLDFVVGAWVFTYLAAPEWFVSNFTPGIMLTVIIITPLLHLTTNIIGYFIGVKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
175 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.242 kDa
Sequence
MLPAYLSNPFAAVFGGGKPIDGGRTYKDGRRILGDGKTYRGLFSGIFCGFLAGCIEIWLSMRGFEIMGIKMPTFGPNYASALIVVLALPSGALFGDMFKSFFKRRMGLKRGASLPLVDQLDFVVGAWFFTYLAAPEWFVSNFTTGIALTVLIMTPLLHLTTNIIGYFIGVKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
175 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.238 kDa
Sequence
MLPAYLSNPFAAVFGGGKPIDGGRTYKDGRRILGDGKTYRGLFSGIFCGFIAGCIEIWLSSRGFEIMGINMPVFGPDYKSALIVVLALASGALFGDMFKSFFKRRMGLKRGASLPLVDQLDFVVGAWVFTYLVAPEWFVSNFTHGIMLTVIIITPLLHLTTNIIGYLIGVKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)
Length
175 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
19.133 kDa
Sequence
MLPAYLPNPFAALFGGGRPIDNGKTMSDGRRILGDGKTYRGFFVGLIFGALAGLMQMQLLEKYPVLFGVELPTFGTGGSNTTILIFALAVGSLFGDMFMSFFKRRMGLKRGAPLPVIDQLDFVLGALIFAYLASPVWFAEQFTFKVIAVILIITPLLHLATNVVGYFIGVKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
174 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
17.953 kDa
Sequence
MALELAVDWRIDNILEAIILMLPAMIANATPVVAGGRRPVDMGVVLPDGRRLLGDGKTIEGLLAGFAAGSAAGVLAALASGNMLLAVHSPAIALGALAGDMAGSFVKRRLGIERGRPAPLLDQLDFYLGALAVSIALGYTWTPRVAVEAAAAVLLLHLAANITAYLLGLKKVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)
Length
174 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.956 kDa
Sequence
MIPAGLANPFAALFGGGTPIDFGKNFKDNRRILGDGKTYRGLIFGSLCGTLIGLLQILLAPHIAPYLAGFIDPSLLVGYSYIALITMPFGALLGDIVKSFFKRRLGFERGAMLPIADQLDFVAGAWVLTFLLDPEWLLANFTIWVAIAVILIIPVFHVAFNIAGYKLGKKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
173 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.347 kDa
Sequence
MVEMGSGAWLELGKGLWFILPAYIANLSACLFGGGRPLDFGKKLSDGRRLLGDGVTIRGFIVGVLAGAVVGLGEGLVVGDPWKAGDGFILGLGAMAGDAVGSFVKRRIGLERGAPAPVLDQLDFFVGAVLLYYLVYGWHPPGWVLVGLAILTLALHWLTNVIGYLLKLKEVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
Length
171 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.724 kDa
Sequence
MGALSSMFWALWYILPAYFANASPVLLGGGRPIDGGRKWRDGNRILGDGKTWRGFLGGVSVGTLVGVLQYYLTPAFYGSLKTAVLLAFLLSFGALMGDLVGSFIKRRLNLPRGYPAVGLDQLGFLISALAFAYPVKTISSGQMLFLLIFTPLVHWGANYFAYKMGWKSVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
171 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.874 kDa
Sequence
MGWLSSIFWAFWYILPAYFANASPVLVGGGRPIDGGRVWRDGRRLLGDGKTWRGFIGGVLIGTLVGIVQYFITPDFYGSLETAVKLAFLLSFGALIGDLVGSFIKRRANLPRGYPAIGLDQLGFLISALAFAYPVKTLSSGQIIFLLVVSPFIHWGANYFAYRMGWKSVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
171 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.29 kDa
Sequence
MNTDIINIIDVLYVIYFMLPAYMANISGLVFGGGKPLDMGITLADGRRLIGDGVTWRGTAAGTFVGLVVGIIQGLLSGSIIIGVITGLLLGFGALMGDAAGSFIKRRLKIDRGRPAPILDQLDFVFGALILVSPIVVLPIDYIILIMLITLVLHLSANIIAYLLGMKDVWY
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Thermococcus onnurineus (strain NA1)
Length
170 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.583 kDa
Sequence
MSLSSLLWAFWYILPAYFANASPVLVGGGRPIDGGRYWKDGRRVFGDGKTWRGLIGGVAIGTAVGALQYFITPEFYGSLGKALLLAFLLSFGALFGDLVGSFFKRRIDLPRGSPAIGLDQLGFLISALAFAYPVKTLDSGQIIFLLVVSPFVHWGANYFAYKMGWKSVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
170 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.951 kDa
Sequence
MKMNQLLEAFWYILPAYFANSSPVVLGGGTPIDFGKKWRDGRRILGDGKTWRGFFGGLIVGTIIGIVQYFLLPEYYGSLGIAIELAFLLSLGTLVGDLIGSFIKRRLNMPRGYPAVGLDQWGFLIAALCFAYPVKTIPTGEVLFLLVITPLIHWGANIFAYKMGWKKVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
168 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.708 kDa
Sequence
MNPIFEAFWYILPAYFANSSPVVLGGGTPIDFGKKWRDGRRIFGDGKTWRGFFGGITVGTVVGTIQHLMFPGYYGSLKLAVGVAFLLSLGALVGDLIGSFIKRRLNMPRGYPAVGLDQWGFLISALCFAYPLRTIPTGEVLFLLVVTPVIHWLANVFAYRMKWKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)
Length
168 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
17.597 kDa
Sequence
MAQLLTPLESILAIIPALAANGAPVLLKYHGTPIDGGKRFLDGRPVLGPGKTWEGLATGILYGSVIALLAASATCNPKLYAAGVFASIGAMLGDMLGAFIKRRLGLERGAPAPLLDQLDFYSGALLALYAAGYVVHPAVALTFTPIVIALHRLTNMAANRLRLKPVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
167 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.511 kDa
Sequence
MHPILEAFWYILPAYFANSSPVILGGGTPIDFGKTWRDGRRIFGDSKTWRGFLGGLTVGTLIGVIQQIIYPYYPSLSLAFKVSFLLALGALVGDLIGSFIKRRLNLPPGYPAVGLDQWGFLISALCFAYPVHTIPTGEVLLLLVVTPLIHWGTNVLAYKMKWKSVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus islandicus (strain M.16.27)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.484 kDa
Sequence
MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.484 kDa
Sequence
MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.484 kDa
Sequence
MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.484 kDa
Sequence
MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.498 kDa
Sequence
MSIAYDLLLSILIYLPAFIANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.484 kDa
Sequence
MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.363 kDa
Sequence
MPIIYYVIFAILYYLPALVANGSAPFVKNGTPIDFRKNFVDGRRLLGDGKTFEGLLVAVTFGTTVGIILAKFLGIYWIYVSFIESLLAMLGDMVGAFIKRRLGLARGARAIGLDQLDFILGATLALIISKISLNIYEFLSIVVIAFVLHILTNNVAYRLKIKSVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.053 kDa
Sequence
MIPAYVPNSAAALFGGGTPIDLGRTFSDGRRVFGDGKTYRGFFGGVVSGVLVGLIEIWAATAFSLSALPQQTFLSVTLLATGALLGDLAKSFLKRRLGKDRGESWFLADQYDLVVGSFLLILIFDPQWLFGTITLPIAVWIVVMTPLLHRVVNIIGYYIGVKEVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
17.806 kDa
Sequence
MLPAYLPNPAAALFGGGTPIDGGRRWSDGRRLLGDGKTWRGLVLGILSGVLLGLIQVSVQDACVFVWLPRHTVLSVLLLAVGALAGDMVKSFVKRRIGKERGAAWPLADQYDLVAGSLLLLLIGDYGFAAVNLTIPVIFWILVLTPLLHRAVNLIGYAIGVKDVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.484 kDa
Sequence
MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)
Length
166 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.185 kDa
Sequence
MLPAYLPNNFAALTGGGMPIDMGRNWTDGRRILGDGKTIRGFVGGVTAGILIGAVQMYAEISGLVPWFPPHTLTAVILLAIGSLLGDMVKSFFKRRQGIDRGGEWFLVDQLDFVVGALLLTLLFDPIWMLNTMTIPLLIVILVLTPLLHRTVNIIGYKLGLKKVPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrobaculum calidifontis (strain JCM 11548 / VA1)
Length
165 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.42 kDa
Sequence
MNEIVQLFLLIWPPYVANGSAVLAARLRRRHPLDFGKNFLDGRRIFGDGKTFEGVAIGVSAGTLLGYAPNLAYSYLTLLDAFLLATAAIVGDLLGAFVKRRLCMPRGYPAFPLDQLDFLLMALLVYSLYRELHIPLLLAAVVLTPVIHRATNYAAYKLRLKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)
Length
165 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.188 kDa
Sequence
MVPAYIPNPVAALCGGGTPIDFCRNYTDGRRILGNGKTYRGLICGVLAGVLIGLVQIWLVGTYHWDLPRQTILSVTLLALGALLGDMGKSFIKRRLGKERGEAWPVADQYDLVVGAFLLTIIFDPAWFFAVVTLPVLIAILVITPVLHRSVNILGYWIKVKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
164 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.394 kDa
Sequence
MDLTVFFLLIWPPYVANGSAVFASRLKWRHPVDFGRNFIDGRRIFGDGKTYEGVAIGIATGTVLGYFPNLVYHVIGVFDAFVLSASAVLGDLIGAFIKRRLCMPRGHPAFPLDQLDFLLTAFLVYSLFREIPVVYVLAAVVITPVIHRATNYVAYLLKLKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length
164 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.195 kDa
Sequence
MDLFVFFALIWPPYVANGSAVLASRLKWRHPVDFGHNFVDGRRLFGDGKTYEGLAIGVVLGTVVGYLPNLLHPTLTLLDALILSVAALLGDLLGAFIKRRLCMPRGHPAFPLDQLDFILMAMLVRSLYADVPVEYIIAASVVTPIIHRATNIAAYILRLKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)
Length
164 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
18.71 kDa
Sequence
MDLLYFFLLIWPPYVANGSAVLANKFKIRHPIDFGKTFVDGRRIFGDGKTYEGFLIGLSTGTFIGYAPNLLYKHLSLLDAFVLSIAALLGDLFGAFIKRRLCMPRGYPAFPLDQLDFLLTSLAVYTLYKDISVEYIIAAVIITPLIHRITNYIAYYLRLKKEPW
Protein
CDP-archaeol synthase: carS

Gene
carS
Protein
CDP-archaeol synthase
Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Length
163 amino acids
Function
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Similarity
Belongs to the CDP-archaeol synthase family.
Mass
17.906 kDa
Sequence
MIGLLLGLIYYIPALVANGSAPFIKSGTPIDFKRKLNDGRRVLGDGKTFEGLLLSLTFGTTVGAIISRFLGIEWIIIGFVESLGAMLGDMLGAFIKRRIGLERGARAPILDQLDFILGATVVLISFNVNLNIYQVVFVCVLVIALHMFTNYVAYRLKIKSVPW
Protein
CDP-archaeol synthase: carS