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Bcep1808_6219

Gene
Bcep1808_6219
Protein
DNA-binding protein Bv3F
Organism
Burkholderia vietnamiensis (strain G4 / LMG 22486)
Length
112 amino acids
Function
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds in the minor groove of AT-rich DNA (PubMed:21673140). Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome. As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes (By similarity).
Similarity
Belongs to the histone-like protein H-NS family.
Mass
12.513 kDa
Sequence
MPVQGRENMDPKSPGYLALIAQRESLDAQIIAARKAEREVAIGQIKALMKEFDLSVLDLQERVQKRNSKRMSTVPKYRDPATGKTWSGRGRQPAWLGNDPAAFLIQPDLPAI