BUD4

Bud site selection protein BUD4

1709 amino acids

Required for establishment of the axial budding pattern in yeast cells. May be involved in the selection of future sites of septation in hyphal cells. Contributes to morphogenesis and is important for induction of hyphal growth. Also plays a role in epithelial adherence, and is involved in intestinal colonization and systemic infection. The role in adhesion is probably minor compared with its role in morphogenesis.

Belongs to the BUD4 family.

192.915 kDa

MQTSISTTTIEDHLHHYSPEESQKLLSRESSINTDLFKHENESVDLLLKEMNSTPSKLLPIDKHSHLQLQPQSSSASIFNSPTKPLNFPRTNSKPSLDPNSSSDTYTSEQDQEKGKEEKKDTAFQTSFDRNFDLDNSIDIQQTIQHQQQQPQQQQQLPQTDNNLIDEFSFQTPMTSTLDLTKQNPTVDKINENHAPTYINTSPNKSIMKKATPKASPKKVAFTATNPEIHHYPDNRVEEEDQSQQKEDSVEPPSIQHQWKDPSQFNYSDEDTNASVPPTPPLHTTKPTFAQLLNKNNEVNSEPEALTDMKLKHENFSNLSLDEKVNLYLSPTNNNNSKNVSDMDSHLQNLQDASKNKTNENIHNLSFALKAPKNDIENPLNSLTNADISLRSSGSSQSSLQSLRDDNRVLESTPGSPKKVNPGLSLNDGIKGFSDEVVESLLPRDLSRDKLETTKENDAPEHNNENFIDAKSTNTNKGQLLVSSDDHLDSFDRSYNHTEQSILNLLNSASQSQISLNALEKQKQIQEQEQTQAAEPEEETSFSDNIKVKQEPKSNLEFVKVTIKKEPVSATEIKAPKREFSSRILRIKNEDEIAEPADIHPKKENEANSHVEDTDALLKKALNDDEESDTTQNSTKMSIRFHIDSDWKLEDSNDGDREDNDDISRFEKSDILNDVSQTSDIIGDKYGNSSSEITTKTLAPPRSDNNDKENSKSFEDPANNESSQQQLEVPHTKEDDSILANSSNIAPPEELTLPVVEANDYSSFNDVTKTFDAYSSFEESLSREHETDSKPINFISIWHKQEKQKKHQIHKVPTKQIIASYQQYKNEQESRVTSDKVKIPNAIQSKKFKEVNVMSRRVVSPDMDDLNVSQFLPELSEDSGFKDLNFANYSNNTNRPRSFTPLSTKNVLSNIDNDPNVVEPPEPKSYAEIRNARRLSANKAAPNQAPPLPPQRQPSSTRSNSNKRVSRFRVPTFEIRRTSSALAPCDMYNDIFDDFGAGSKPTIKAEGMKTLPSMDKDDVKRILNAKKGVTQDEYINAKLVDQKPKKNSIVTDPEDRYEELQQTASIHNATIDSSIYGRPDSISTDMLPYLSDELKKPPTALLSADRLFMEQEVHPLRSNSVLVHPGAGAATNSSMLPEPDFELINSPTRNVSNNSDNVAISGNASTISFNQLDMNFDDQATIGQKIQEQPASKSANTVRGDDDGLASAPETPRTPTKKESISSKPAKLSSASPRKSPIKIGSPVRVIKKNGSIAGIEPIPKATHKPKKSFQGNEISNHKVRDGGISPSSGSEHQQHNPSMVSVPSQYTDATSTVPDENKDVQHKPREKQKQKHHHRHHHHKQKTDIPGVVDDEIPDVGLQERGKLFFRVLGIKNINLPDINTHKGRFTLTLDNGVHCVTTPEYNMDDHNVAIGKEFELTVADSLEFILTLKASYEKPRGTLVEVTEKKVVKSRNRLSRLFGSKDIITTTKFVPTEVKDTWANKFAPDGSFARCYIDLQQFEDQITGKALQFDLNCFNEWETMSNGNQPMKRGKPYKIAQLEVKMLYVPRSDPREILPTSIRSAYESINELNNEQNNYFEGYLHQEGGDCPIFKKRFFKLMGTSLLAHSEISHKTRAKINLSKVVDLIYVDKENIDRSNHRNFSDVLLLDHAFKIKFANGELIDFCAPNKHEMKIWIQNLQEIIYRNRFRRQPWVNLMLQQQQQQQSSQQ

BUD4

Bud site selection protein 4

1447 amino acids

Required for establishment of the axial budding pattern in haploid cells. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate axial budding and cytokinesis. Involved in the septin organization at the bud neck.

164.486 kDa

MHDAESTVDSLLKEIDNEMEQTKSNITQNGSEDTPHNWKLPLQEIGDDTMEMLVKHNTRSNATENSRGRSPSKMSTISNESLNLGLLRVNSELEESPAAVHQERIKNSVANGALGHANSPKVLNNLKNMAQDIDKLARDEEKPVKLSSSPLKFTLKSTQPLLSYPESPIHRSSIEIETNYDDEDEEEEDAYTCLTQSPQILHSPSRIPITNAVSINKLNLDFTLNPNESDKSLVSDTSVDSTGRELDTKTIPELPFCMSSTPEMTPVDEKCNLPSKLLNTSNNSHSDSRSPTASVEDLNISTNLPGADSSQNNPVTTDADALIENDVVRDLQQNMEHIDDAFDEKKVLDEGCSNEPVTFLGENDTRSIVYSNKGTNANVQEFSQEDSLAHSEPKFKDLNATSDDVWNEDKETDANISTSTKSEESYIADYKVTRQEDWDTKKLHQESEHANEQPAIIPQKDSSEETFTELNNESEFQRNFKDGEEYRIVQHEESLYGQRTKSPEENIINGSEIGVDHGEAAEVNEPLAKTSAEEHDLSSSCEDQSVSEARNKDRIEEKEVETKDENIETEKDESEYHKVEENEEPEHVPLLPPLPRWEEIQFNEPFIDENDTSNDSIDLTRSMKPSDYISIWHIQEEEIKSNSPESIANSQFSQQSSITTASTVDSKKDNGSTSFKFKPRIVSRSRIYNPKSRVSSLNYYDNEDYILSNSEWNALDPMRRNTLISKRIQDNIRTQKGHAPLIRPSIMKLNGEDSGFQNHFLEVEQPQEHENIPLSTHLSEQDITTNVGLDEQKLPTNTQDEAEISIREIESAGDITFNRGDLLSLSFDEELGQDFANFLDALDHDSTSFNHGPDDSSSFQRDSSKKSFNSLWESSYELKPPPSIRKQPIAPDVLQKLLESDTKDDADLEKIREERITEPRTGLGIGMLKTPVKDVSIALAASIKGYEASFSDTDSRPEGMNNSDAITLNMFDDFEEDKMTPSTPVRSISPIKRHVSSPFKVVKAGNKQENNEINIKAEEEIEPMTQQETDGLKQDIPPLLAQTKDNVEAKEETITQLEEPQDVEQEFPDMGTLYLSIKAISTLALYGTKSHRATYAIVFDNGENVVQTPWESLPYDGNIRINKEFELPIDFKGKAETSSASSERDSYKKCVITLKCKYEKPRHELVEIVDKVPVGKSFFGKTKYKFEKKYVQKKPKQDEWDYLFAQDGSFARCEIEINEEFLKNVAFNTSHMHYNMINKWSRIADKIHGSKRLYELPRKAPHKVASLDVEACFLERTSAFEQFPKQFSLVNKIVSKYKLQQNIYKEGYLLQDGGDLKGKIENRFFKLHGSQLSGYHEISRKAKIDINLLKVTKVLRNEDIQADNGGQRNFTDWVLFNECFQLVFDDGERITFNAECSNEEKSDWYNKLQEVVELNVFHQPWVKKYCEKLAEEEKTRTTGHNLKQDFN

BUD4

Bud site selection protein 4

1447 amino acids

Required for establishment of the axial budding pattern in haploid cells. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate axial budding and cytokinesis. Involved in the septin organization at the bud neck (By similarity).

Belongs to the BUD4 family.

164.353 kDa

MHDAESTVDSLLKEIDNEMEQTKSNITQNGSEDTPHNWKLPLQEIGDDTMEMLVKHNTRSNATENSRGRSPSKMSTISNESLNLGLLRVNSELEESPAAVHQERIKNSVANGALGHANSPKVLNNLKNMAQDIDKLARDEEKPVKLSSSPLKFTLKSTQPLLSYPESPIHRSSIEIETNYDDEDEEEEDAYTCLTQSPQILHSPSRIPITNAVSINKLNLDFTLNPNESDKSLVSDTSVDSTGRELDTKTIPELPFCMSSTPEMTPVDEKCNLPSKLLNTSNNSHSDSRSPTASVEDLNISTNLPGADSSQNNPVTTDADALIENDVVRDLQQNMEHIDDAFDEKKVLDEGCSNEPVTFLGENDTRSIVYSNKGTNANVQEFSQEDSLAHSEPNFKDLNATSDDVWNEDKETDANISTSTKSEESYIADYKVTRQEDWDTKKLHQESEHANEQPAIIPQKDSSEETFTELNNESEFQRNSKDGEEYRIVQHEESLYGQRTKSSEENIINGSEIGVDHGEADEVNEPLAKTSAEEHDLSSSCEDQSVSEARNKDSIEEKEVETKDENIETEKDESEYHKVEENEESEHVPLLPPLPRWEEIQFNEPFIDENDTSNDSIDLTRSMKPSDYISIWHIQEEEIKSNSPESIANSQFSQQSSITTASTVDSKKDNGSTSFKFKPRIVSRSRIYNPKSRVSSLNYYDNEDYILSNSEWNALDPMRRNTLISKRIQDNIRTQKGHAPLIRPSVMKLNGEDSGFQNHFLEVEQPQEHENIPLSTHLSEQDITTNVGLDEQKLPTNTQDEAEISIREIESAGDITFNRGDLLSLSFDEELGQDFANFLDALDHDSTSFNHGPDDSSSFQRDSSKKSFNSLWESSYELKPPPSIRKQPIAPDVLQKLLESDTKDDADLEKIREERITEPRTGLGIGMLKTPVKDVSIALAASIKGYEASFSDTDSRPEGMNNSDAITLNMFDDFEEDKMTPSTPVRSISPIKRHVSSPFKVVKAGNKQENNEINIKAEEEIEPMTQQETDGLKQDIPPLLAQTKDNVEAKEETITQLEEPQDVEQEFPDMGTLYLSIKAISTLALYGTKSHRATYAIVFDNGENVVQTPWESLPYDGNIRINKEFELPIDFKGKAETSSASSERDSYKKCVITLKCKYEKPRHELVEIVDKVPVGKSFFGKTKYKFEKKYVQKKPKQDEWDYLFAQDGSFARCEIEINEEFLKNVAFNTSHMHYNMINKWSRIADKIHGSKRLYELPRKAPHKVASLDVEACFLERTSAFEQFPKQFSLVNKIVSKYKLQQNIYKEGYLLQDGGDLKGKIENRFFKLHGSQLSGYHEISRKAKIDINLLKVTKVLRNEDIQADNGGQRNFTDWVLFNECFQLVFDDGERITFNAECSNEEKSDWYNKLQEVVELNVFHQPWVKKYCEKLAEEEKTRTTGHNLKQDFN

BUD4

Bud site selection protein 4

1446 amino acids

Required for selection of future bud sites. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate budding and cytokinesis. Involved in the septin organization at the bud neck (By similarity).

Belongs to the BUD4 family.

162.081 kDa

MEAETTVDSLLKEIDMEMEMQSGNDVAQSNGYLLPLQEIGDETMDMLVQYNTENNANSNVNANANANANQWNKVDDPQDLLPMENNYDDDEEQGDESDTTNLLSGNKHLTEEESEQVLVDSKNLVLPPSSSKSNLINNLKQVVEDEVSDSQLSNDMDDTRTLNFSVKGTEPLLADELQDKEPDMIEVSTIYDGPDMISMADDSDTEDIDLLSKAKKPVSPSKIPITNAQTINYFKDAPVEDAKLQTVPDDIPLETKQTTVSNDILSNVETLLPPTLERPSFVISNLKEASQSVENLGFPDYEEDSQSEQETSVLHHTPTDFHAHEFEVFATELPDINVTPSIKPIDIDNNCEHENRLVSEEESKGVISSVPENENLPAVKSNPSSNSISDMLEIRQENKLDETLNMIDHQLSSNKSIDSVKTVSDNNISKSANDGSVEDVADSGKETSDIARNIEESHNSLINLTSGNNFDQSMHNDLIEESNTRVNVTESDITASEDSFNGSHDQNSSLNNLTKNDNGIQQNLEDNHTGIQPEMVVPEEVTTTLPEVNILPASENMLENTSESEISVQFLQNRDNEDKVSSDPQLEENIRSTETVMNTQETFEPKPAKKNQYTDREIEVLNSQKDISEATDNSAVNSRISSSASNFTPVLPPLPKLEKLSIDDPFDDEFETSNESMQMKNSVKPTDYLSIWHLQEQTTKAVSPALSSNSQFSYNSNSTKSSVASPVPATAFKFKPKIVSRSKYYYPDNNIQQEQSMDFIYTKLPSILDPMRRNTINSKKIRQTVIDKRKSHPSFSVDEGNTITEVNIEPEVKVQPISIENDSSSLKANNQDDNESCSSGSQAFVTPSATMDNFDSQFNELGTSFENDLENVLNYFDKDINTNTSSDLIEETTTKNQALPTSKVWSESVDYSLPTGEEPNVDHNIMKKLLNTENSELNECRSDQEHHIIDNAGLGIWRSTANDIATGNVDMFALNGRDISISKSEMTNDIDMGIFSDKKSLVHTPELSPVKSTHVGSPFKVISPKKNTQKDLKDGTTAEKRVSSESEAAQISIMSAVGEITNKDTAVVDDASNKDNIDAGQVGNEGEPIVDKGLLYLHLQGTTKLSLAGINAHHPKYSIEFDNGKNVVRTDWTELDSRGTISLNKEFEIPIDQSINKLIITLMIKYTRLTNELVEVTKRIPIGKKFPFGKMKYRTETQFVERSTVKDEWDYLFARDGSFGRCEILLDESLFEKIRFKEQDLSFDLLNKWSRLQNNSSSKVTQEALYDLPRRPAYKVGSLKVKGCFLERVSNDEKFPVSLKKAKSIVEKYRSQQDITKEGYLLQEGGDLSSQMKNRFFKLNGVELVGYHEVSMKPKIRINMLKVVKVIGKDDVVTGKDNVRNFTTWVLMNDCFQLVFDDGEVITFSDESSLADEQSWYMKLKEVVELNAFHQPWVKRFSENMIINDI

BUD4

Bud site selection protein 4

1378 amino acids

Required for selection of future bud sites. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate budding and cytokinesis. Involved in the septin organization at the bud neck (By similarity).

Belongs to the BUD4 family.

155.327 kDa

MIPNDAEGAMDSLLKEIDHEMEVTIGTIDAQEDHSKQKEETEATNQQTWKLPLQDIGDETMDMLVKHNTKNNVINPNFNKKDVDTNESPKNNNDKNVVFNDNVQLLELSANMDESVLMSTPTKSDIDISPNKVLINLGDDIANESNEDNKLPLDNKTESEDSDLVSTMLLSKIPITHTENINDFYEKKSTDIRASTSRISSVSSDIEGTPLPTTVQTDQFELLKQAMKQTFEEDNNSNIDISPLKESLLSSELKTKQNLSIEQNEETSVDSIDNSVIHNSEYEVHARSNEREEENENDFENSIEDLEISTHVIEKSPSIEAISTLDPNTDNNKEHFIINNITKDSTFIEVTSDSKIQIDLKDSPENTLHTNEDQKEANTENVASETNIKETDQVIHIPTLTEEEISTITNITNDTETTEEGSKAEEDAKNSDVSNSQNSESINTTITNSLIGIDQNLTNKSSDITNDYEEPPKENELKSSPDVIEKGHSSIEHFDDEKITNSSALGTSNYISIPLDTLQEATPVTDSGKTFELQNQDSDNINSERIQNLNGSTPVEEKFNADDELLKTNQSHITQNKDKSNINEIDNSGTTSIVSDHVVAPILPPLPKIDKIFIDDPFGEEYDISNDSIDLTKSTRPGDYLSIWHIQEEELKQVSPASTTNSQFSNRILSNASSNASAESRISSTAFKFKPRIVSRSRYINPESRVNSFNISEEMILPQLYGALDPMRRSSRMSRTIQNSIKANRQKSEQYAGTRKYSIEIQPNQESRISSRIISNKLEEVSSENDKVETMNNSITMDGSFQLLPSFLDNSFGEQLDLTFSKFAKDVLSLRSSSLAQSEIHDNSINIWGEDNFIGNTSKNNDHNAMLDSKNKLLEVTDDEKSISESINKDIFADGILKSSIFNDITVSRGLNINGLDVDLSDSESVRVSLLTAETDASESGTPIKNTVKDSHVSSPFKVVNISKWKNQDGPESDHEVEEIAEIQIEAEKSSESIADISPIKMKPFVDTVVIEEPSQTALVDAGSLYLKLKGCLNIKLTGIKHHDARYCFEFDNGRNSIQTAWAVIPSDGDIRVNHDFESTVFEVGSKLYVTLKCKYTPPKTEIVEVVEKVLIPKKKLFGKAEYKYEKRFVQRDSKKDEWNNLFARDGSFGRAEVLLDHTFLNSVKYNKRNCTFDMMNEWTRLNDKENIENVFNIPRKPKYKVADLKMEVCYLDRVSNKEVFPVSFDKCEMIIKKYKEQLLISKEGYLMQEGGDVCNNLVRRFFKLQGTDLIGYHEVSNLPVVTINMLKVIDVVSSDDLKEEEGKQRSGNSKRNFTDHVLFGGCIQLVFTDEEVINLYADTSAQEKIEWYSKLKKTVDLNICHQPWVTKLAEAQKLEEC

BUD4

Bud site selection protein 4 homolog

1259 amino acids

May be involved in the septin organization at the site of septation.

Belongs to the BUD4 family.

140.622 kDa

MDEQSSGQDVDQSLDTLLKEIDLKMQLRDGEEGRRASAQSEGSLRLPAVRMLERGMVASASHKSVTFDEEPPSVHEYSVVMDSSAGTSECAEEEREGADGYECAADTMRVLYDEDTDSSCMGSERALAGPAAEGIVPEGYKEADLLGTERAGSGTPSLSYDDAAGLGSPPHVIFTIKPTSPLNAYDRGSWEPLQSNTAMDTPPRGGTAVSQHGLFAKAPKLPAIPSPNSRRRVSYAGSDSYPSDDSATDKRSLTDKTVPDNRGENERGGFGYENSDRNPSIETGTTDEYQSAGEYKSMSSSEANDDSKTEASVEDLRISNKPQRDTTIQDLHATTLPRSSSTLIPPALPPLDPSFFGRLARSPSYSPIRDRGSSEGSVGEHDSSLEQDHELGMGQQSARTNSSASGNSSDSVMVKPLSLFSNSQVDSLHLGAPAPDNSTPNKEALPSACPPDAMKSIGTQTSILEDKAESGPSQSSATSEKSVMLPNFPRFESFFDDSYPFGHDSDRSNNSVSYSKRTLKPSNYLSIWHLQEAQMRHDSPAFSANSQFSCKMVGESKRTSLESSRLSAKYESRFKFKFKPKLVSRRRIYYNKDQWRNFQEPPTRYYSNCTESDHISSDVPGTPVSPSIKSRNLCHGRTRGNMKMVERVNSLCSANERLSSAGNGDETFLSASSNLDVTSRRPSVDIISEISTKDLLPKIKQDSDGFNELIKTFVDHDEQSQQTDSTIASYRRGTRDTTIYHIWEHSIQENSISDYGNSPTAGKGTISKLLDNHEVEFDGKNSFVTGLGIIKKTDQDSRVDVLRIDSTQGIEAIQSFSPYSYRNAFDPVTPTKSAYHGCEALQASQMGTPFRPAISTTLQAQSGLGHKRPAVERPTTAQLGNYVSAEMSPEVQEPAEETKKRTDLQDNGQLYFVFVGIEQLALRDIERHSAECSIEFDNGNNVVQSEWLPLPKSGSMSLNQEYSVIIAEESLPNMIITLKCRYKSPKKELVEITEKVPLKSKCCGLGKPKYKQVKKLLRREMDFDEWDYKIAQDGSFARCKEQIDEELLKNVRYKKQQFRWTLLSEWERDHSKEHKRKRAWELPRLPAHPAGALVVDMCYLPRTSRFEKFPKTLQIARRVVNKFKEQKAIAMEGFMWQEGGDTEVLKRRYFTLNGTQLVAHHEITKKPKAMINLLRVEKLLTEAEISREMLSSSSRCFTDLVLLHECFVLFFENGEEIMFNPDTKTEKLEWIEKLRKVIELNRFHQPWVKKFLNSSENIL

BUD4

Bud site selection protein 4

1217 amino acids

Required for selection of future bud sites. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate budding and cytokinesis. Involved in the septin organization at the bud neck (By similarity).

Belongs to the BUD4 family.

138.459 kDa

MQMEDKGEALNPDAMYSLLKEIDQEISHTDNISIDQLPEEDTLDNEKKIDASENVIENTEEEALQLGDESANTTTEIKETSCTEDHDTVENTEDVISMAEGLDKAPLETAWIKHNYQQTKPVVSKRLISNDGSDTSVEDINASTRIPSYTSEEITGLELKDKMVTDVGERLSHFLDQKYAENPNLPALKGMLSMADEKAMEDDPKKDKPLVFTIEPTKPLFPSKEVSSTMIQVEIHTPDEDDVDGAAADTKEATNLLLDSKIPVTPNVCINRFVNNNGETRVSSGSSTEDAQELNTHRFQDRYHLLSGAQAVPQLPQLPALTLQDYKSSSVQSVNASRIFSVATTNDNYQSAKEYDLSSTVGCEELSDDASVKDLEIPEPNELPCFPTFQLDSTSMKTSSSMETVQHDKAKFNSDVNIADDTMEQIEQEEAELISNPERSGSPTNDNMSQHSQNRQLLGVSEVSQAQQAPEHHVEMSVEFQDEGRRDITSSFSRESDRIELPPLPPMNGLSTMFDQDLFNDHETSHESIDLTSSSHKENYLSIWHSQKTGGSFISPALSTNSQFSTQSRTSSVPTNHSGSSFKFKSRIISNSHVFKQEAFRQFSDEYVLSTQDDSKLDPLRRNTIMSKRIQQELKTQAKMYPFANKFALDESSEPSIHNESIITGDISRTSDKAVDTTNILSHKNLTLLPPQSTETVFSSFLDNFDKDDFEEKLAEESRLNSKKNLQTTWGHFRDVSSGNVDIKATQQQIAEVLHNQNEDVVQVGSHIQDVKVLLGNEIEGYDVQKSVSDLSVETTKKSPIKHVGSPFKVKARSETPPQSPVVYERDTTEVNEGLQRAPTTSLASVYLENSLQEFESSELQDHGKLYLKLKSINSLRLQQIKRHNAKYCIEFDNGKEVIETPWESIPEDGPIKMSQEFEVNMESNNVTLFMTMKIRYTSPQNQLTEVVEKIPIKKRFAFGKTKYRLEKRFVTKKLKYDDWDFKFAKDGSFARCQVNVNKNMLKQIKYKTNELHFEFLNEWEREFDEKIAQTYKEDELWKLPRKNPSKVCSLTVDVMYLPRTSSMERFPKNLKAVQKCCEKYLEQQRVNNEGFLWQEGGDVEGMLKRRYMILKGTELIAHDEVTRKPQTLLNLLNVVDIYSDGKTATGKQMRNFTDMVLFSDCFKLLFANDEVINFNADSNLLKQQWVEILTSVVELNKFHQPWIKRVFENEQYNITF